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Taking the Stage: Scientific Conferences
Our scientists and clinicians are global experts in their field. The University of Kansas Cancer Center faculty present their work at dozens of scientific conferences each year.
Media inquiry? The cancer center communications team works with media to facilitate information requests and connect them with experts. Learn more.
Recent and Past Conferences
Abstracts listed below involve KU cancer center members and consortium partners Stowers Institute for Medical Research and Children’s Mercy.
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*The below content was pulled from currently available information on ASTRO's website as well as supplied by KU Cancer Center members.
September 29, 2024
PS 03 - Presidential Symposium: Innovations in Genitourinary Cancers: Session III - Radiotherapy for Prostate Cancer: Innovations You Can Implement Today
Session Date/Time: September 29, 11:10 AM - 12 PM
Session Location: Ballroom A/B/C
Moderator: Ronald Chen, MD, FASTRO, MPH
SS 04 - PRO/QoL/Survivorship 1: New Frontiers in Patient Reporting Outcomes and Survivorship
Session Date/Time: September 29, 2:45 - 4 PM
Session Location: Room 204
Moderator: Tamara Vern-Goss, DO, FAAP and Xinglei Shen, MD
October 1, 2024
EDU 56 - Perspectives from a Physicist, Biologist and Clinician: Unrealized Opportunities in Spatially Fractionated Radiotherapy
Session Date/Time: October 1, 5:15 - 6:15 PM
Session Location: Room 145
Moderator: Gregory Gan, MD, PhD
October 2, 2024
QP 20 - Phys 11: Hadrons
Session Date/Time: October 2, 8 - 9 AM
Session Location: Room 147
Moderators: Lei Dong, PhD and Hao Gao, PhDAbstracts/Posters
Interim Futility Results of NRG-HN005, A Randomized, Phase II/III Non-Inferiority Trial for Non-Smoking p16+ Oropharyngeal Cancer Patients
Author(s): Sue Yom, Chris LominskaNational Survey of Factors Influencing Specialty Selection among Medical Students Interested in Oncology Careers
Poster Viewing Q&A Session Time/Date: Sunday, September 29, 2:45 PM-4:15 PM ETAuthor(s): Krishna Reddy, Andrew Hoover
Re-irradiation for Local Recurrence
Presidential Symposium PresentationSession Date: September 29, 2024
Author: Ronald ChenProstate cancer survivors’ long-term supportive care needs: results from a population-based cohort.
Quick Pitch Oral Presentation
Author(s): Y Xie, Xinglei Shen, Ying Cao, Aaron Katz, Rahul Mali, Kate Kane, Deborah Usinger, S Walden, Ronald ChenAssociation of patient comorbidities with treatment regret in prostate cancer: results from a population-based prospective cohort
Poster Presentation
Author(s): Rahul Mali, Ying Cao, Aaron Katz, Deborah Usinger, Xinglei Shen, Ronald ChenFinancial toxicity among long term survivors of prostate cancer
Poster Presentation
Author(s): Kate Kane, Aaron Katz, Ying Cao, Rahul Mali, Deborah Usinger, Ronald Chen, Xinglei ShenPatterns of Care of Brain Metastasis for NSCLC in the Era of Immunotherapy
Author: Sunitha Varghese (PGY3) -
*The below content was pulled from currently available information on ASCO's website as well as supplied by KU Cancer Center members.
May 31, 2024
Recurrence score gene axes scores and outcomes by race and ethnicity in the RxPONDER trial.
2:45 pm – 4:15 pm
E451 | On Demand
Rapid Oral Abstract Session
Session Title: Breast Cancer—Local/Regional/Adjuvant
Track: Breast Cancer
Abstract: 515
Yara Abdou, Jess Hoag, William Barlow, Julie Gralow, Funda Meric-Bernstam, Kathy Albain, Daniel Hayes, Nancy Lin, Edith Perez, Lori Goldstein, Stephen Chia, Sukhbinder Dhesy-Thind, Priya Rastogi, Anne Schott, Jennifer Racz, Debashish Tripathy, Gabriel Hortobagyi, Lajos Pusztai, Priyanka Sharma, Kevin Kalinsky
June 1, 2024
Interim safety and efficacy of BP1001 in a phase II acute myeloid leukemia (AML) study.
8 am – 9:30 am
E450b | On Demand
Rapid Oral Abstract Session
Session Title: Hematologic Malignancies—Leukemia, Myelodysplastic Syndromes, and Allotransplant
Track: Hematologic Malignancies
Abstract: 6511
Maro Ohanian, Maher Abdul-Hay, Tara Lin, Ellen Ritchie, Vamsi Kota, Miranda Lim, Sherry Pierce, Michael Hickey, Ana Tari Ashizawa, Hagop Kantarjian, Jorge Cortes, Gail Roboz
A phase 2 clinical trial of first-in-class fascin inhibitor NP-G2-044 as monotherapy and in combination therapy with anti-PD-1 immunotherapy in patients with advanced solid tumor malignancies.
9 am – 12 pm
Hall A | On Demand
Poster Session
Session Title: Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology
Track: Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology
Abstract: 3112, Poster Bd #: 257
Frank Tsai, Michael Birrer, Jason Brown, Sanjay Chandrasekaran, Vincent Chung, Richard Frank, Edward Garmey, Shirish Gadgeel, Thomas George, Shadia Jalal, Andrew Poklepovic, Jennifer Segar, Alexander Spira, Jue Jillian Zhang, Anup Kasi
A phase I study of irinotecan combined with BAY1895344 (ATR inhibitor) in advanced solid tumors: Results of ETCTN 10402 dose escalation.
9 am – 12 pm
Hall A | On Demand
Poster Session
Session Title: Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology
Track: Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology
Abstract: 3077, Poster Bd #: 222
Thatcher Heumann, Shannon Stockton, Michael Cecchini, Raid Aljumaily, Cathy Shyr, Jennifer Whisenant, Jason Starr, Farshid Dayyani, Joaquina Baranda, Nikolaos Trikalinos, S. Ivy, Patricia LoRusso, Satya Das, Steven Gore, Jan Beumer, Jordan Berlin
An open-label, phase 1, multicenter study to evaluate the safety and preliminary anti-tumor activity of NT 112 in human leukocyte antigen-C*08:02–positive adult patients with unresectable, advanced, and/or metastatic solid tumors that are positive for the KRAS G12D mutation.
9 am – 12 pm
Hall A | On Demand
Poster Session
Session Title: Developmental Therapeutics—Immunotherapy
Track: Developmental Therapeutics—Immunotherapy
Abstract: TPS2677, Poster Bd #: 152a
Salman Punekar, Meredith Pelster, Carlos Becerra, J. Hecht, Andrew Paulson, Patrick Grierson, Maria Pia Morelli, Rom Leidner, Mandana Kamgar, Joaquina Baranda, Syed Kazmi, Ardaman Shergill, Anne Robinson, Anuradha Patel, Ying Yan, Jeroen van Heijst, Nathan Demars, Arianne Perez, Sarah Cohen, Marwan Fakih
Two phase 2A clinical trials to evaluate the safety and efficacy of IMSA101 in combination with radiotherapy and checkpoint inhibitors in oligometastatic and oligoprogressive solid tumor malignancies.
9 am – 12 pm
Hall A | On Demand
Poster Session
Session Title: Developmental Therapeutics—Immunotherapy
Track: Developmental Therapeutics—Immunotherapy
Abstract: TPS2685, Poster Bd #: 156a
Percy Lee, Jyoti Malhotra, Jason Salsamendi, Mona Arbab, Tithi Biswas, Andrew Baschnagel, Matthew Deek, Edward Garmey, Daniel Hamstra, Mai Anh Huynh, Aryavarta Kumar, Devalingam Mahalingam, Benjamin Maughan, Teresa Mooneyham, Nitin Ohri, Krishna Reddy, Gregory Vlacich, Patrick Widhelm, Jason Ye, Robert Timmerman
ATHENA: A phase 1/2 study of AZD5851, a chimeric antigen receptor (CAR) T-cell therapy directed against GPC3 in adult patients with advanced/recurrent hepatocellular carcinoma (HCC).
9 am – 12 pm
Hall A | On Demand
Poster Session
Session Title: Developmental Therapeutics—Immunotherapy
Track: Developmental Therapeutics—Immunotherapy
Abstract: TPS2675, Poster Bd #: 151a
Ashley Hamilton, Robin Kate Kelley, Daneng Li, Ignacio Melero Bermejo, Ghassan Abou-Alfa, Olatunji Alese, Raed Al-Rajabi, Hani Babiker, Mitesh Borad, Farshid Dayyani, Martin Gutierrez, Jung Yong Hong, Lionel Aurelien Kankeu Fonkoua, Thomas Karasic, Adel Kardosh, Bridget Keenan, Anne Noonan, Anwaar Saeed, Attilio Bondanza, John Stone
Association between beta-catenin (CTNNB1) mutations and clinical outcomes of pembrolizumab in advanced hepatocellular carcinoma (aHCC): Exploratory analyses from KEYNOTE-240.
1:30 pm – 4:30 pm
Hall A | On Demand
Poster Session
Session Title: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary
Track: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary
Abstract: 4109, Poster Bd #: 89
Masatoshi Kudo, Ann-Lii Cheng, Philippe Merle, Baek-Yeol Ryoo, Thomas Decaens, Irfan Cicin, Olav Dajani, Raed Al-Rajabi, Jean-Marie Peron, Stephen Chan, Jennifer Knox, Bruno Daniele, Leah Suttner, Andrea Webber, Carol Pena, Razvan Cristescu, Cai Chen, Ken Hatogai, Abby Siegel, Richard Finn
Association of circulating DNA with recurrence in CRS-HIPEC patients with colorectal and appendiceal peritoneal carcinomatosis: Insights from a phase II randomized trial.
1:30 pm – 4:30 pm
Hall A | On Demand
Poster Session
Session Title: Gastrointestinal Cancer—Colorectal and Anal
Track: Gastrointestinal Cancer—Colorectal and Anal
Abstract: 3598, Poster Bd #: 261
Anup Kasi, Raed Al-Rajabi, Weijing Sun, Joaquina Baranda, Haoran Li, Jo Wick, Sanjana Mullangi, Kenda Eberhardt, Shannon Bradbury, Rebecca Romero, Erin Carroll, Lori Barbosa, Mazin Al-Kasspooles, Anwaar Saeed
Reduced dose fludarabine/cyclophosphamide lymphodepletion for tumor-infiltrating lymphocytes therapy (LN-144, lifileucel) in metastatic melanoma.
1:30 pm – 4:30 pm
Hall A | On Demand
Poster Session
Session Title: Melanoma/Skin Cancers
Track: Melanoma/Skin Cancers
Abstract: TPS9608, Poster Bd #: 387b
Muhammad Umair Mushtaq, Haitham Abdelhakim, Luke Selby, Sunil Abhyankar, Joseph McGuirk, Gary Doolittle
Perioperative therapy for resectable and borderline resectable pancreatic adenocarcinoma: An AGICC clinical trial.
1:30 pm – 4:30 pm
Hall A | On Demand
Poster Session
Session Title: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary
Track: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary
Abstract: 4175, Poster Bd #: 155
Deirdre Cohen, Judith Goldberg, Lawrence Leichman, Tsivia Hochman, Elliot Newman, Kevin Du, Alec Megibow, Paul Oberstein, Raed Al-Rajabi, Aaron Scott, Tanios Bekaii-Saab, Wells Messersmith, Colin Weekes
ETCTN 10366: A phase 1 study of DNA-PK inhibitor peposertib in combination with hypofractionated radiotherapy for the treatment of locally advanced pancreatic adenocarcinoma.
1:30 pm – 4:30 pm
Hall A | On Demand
Poster Session
Session Title: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary
Track: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary
Abstract: 4168, Poster Bd #: 148
S. Lindsey Davis, Anup Kasi, Farshid Dayyani, Allyson Ocean, Vincent Chung, Mohammed Najeeb Al Hallak, Christos Fountzilas, Junxiao Hu, Judy Murray, Carmen Allegra, Steven Gore, Jan Beumer, Karyn Goodman
Enfortumab vedotin (EV) in previously treated gastric/esophageal cancers cohorts of EV-202.
1:30 pm – 4:30 pm
Hall A | On Demand
Poster Session
Session Title: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary
Track: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary
Abstract: 4046, Poster Bd #: 26
Kei Muro, Keisho Chin, Steven Maron, Fadi Braiteh, Seiichiro Mitani, Hiroki Hara, Yasutoshi Kuboki, Mary Mulcahy, Joaquina Baranda, Faithlore Gardner, Ning Jin, Satoshi Hamauchi, Jason Kaplan, Seema Gorla, Shubin Liu, Michele Wozniak, Changting Meng, Shunsuke Kondo
Correlative results from NCI CTEP/ETCTN 10330: A phase 2 study of belinostat with SGI-110 (guadecitabine) or ASTX727 (decitabine/cedazuridine) for advanced conventional chondrosarcoma (cCS).
1:30 pm – 4:30 pm
Hall A | On Demand
Poster Session
Session Title: Sarcoma
Track: Sarcoma
Abstract: 11526, Poster Bd #: 452
Kristine Lacuna, Matthew Ingham, Li Chen, Biswajit Das, Shing Lee, Liner Ge, Mihaela Druta, Anthony Conley, Mary Louise Keohan, Mark Agulnik, Melissa Burgess, Anna Chalmers, Gina D'Amato, Benjamin Powers, Mahesh Seetharam, Brittany Siontis, Lorraine Pelosof, Brian Van Tine, Gary Schwartz, Mia Weiss
Health-related quality of life (HRQOL) results from PRESTO (AFT-19), a phase 3 randomized trial of intensification of androgen blockade in patients with high-risk biochemically relapsed castration sensitive prostate cancer.
3 pm – 6 pm
Arie Crown Theater | Live Stream
Oral Abstract Session
Session Title: Genitourinary Cancer—Prostate, Testicular, and Penile
Track: Genitourinary Cancer—Prostate, Testicular, and Penile
Abstract: 5006
Ronald Chen, Gina Mazza, Briant Fruth, Han Xiao, Joel Picus, Mary Taplin, Tanya Dorff, Leonard Appleman, Douglas Weckstein, Akash Patnaik, Alan Bryce, Daniel Shevrin, James Mohler, Daniel Anderson, Arpit Rao, Alan Tan, Charles Ryan, Scott Eggener, Michael Morris, Rahul Aggarwal
Enfortumab vedotin (EV) in triple-negative breast cancer (TNBC) and HR+/HER2- breast cancer (BC) cohorts of EV-202.
3 pm – 6 pm
Hall B1 | Live Stream
Oral Abstract Session
Session Title: Breast Cancer—Metastatic
Track: Breast Cancer
Abstract: 1005
Antonio Giordano, Arif Ali Awan, Justine Yang Bruce, Hope Rugo, Jennifer Diamond, Yelena Novik, Joaquina Baranda, Kei Muro, Makiko Ono, Rita Nanda, Jason Kaplan, Seema Gorla, Shubin Liu, Michele Wozniak, Anthony Lee, Tiffany Traina
Efficacy and safety of ibrutinib plus venetoclax in patients with mantle cell lymphoma (MCL) and TP53 mutations in the SYMPATICO study.
3 pm – 6 pm
S100bc | Live Stream
Oral Abstract Session
Session Title: Hematologic Malignancies—Lymphoma and Chronic Lymphocytic Leukemia
Track: Hematologic Malignancies
Abstract: 7007
Michael Wang, Wojciech Jurczak, Marek Trneny, David Belada, Tomasz Wrobel, Nilanjan Ghosh, Mary-Margaret Keating, Tom van Meerten, Rubén Fernández-Álvarez, Gottfried von Keudell, Catherine Thieblemont, Frederic Peyrade, Marc Andre, Marc Hoffmann, Maoko Naganuma, Edith Szafer-Glusman, Jennifer Lin, James Dean, Jutta Neuenburg, Constantine Tam
Cabazitaxel with abiraterone versus abiraterone alone randomized trial for extensive disease following docetaxel: The CHAARTED2 trial of the ECOG-ACRIN Cancer Research Group (EA8153).
3 pm – 6 pm
Arie Crown Theater | Live Stream
Oral Abstract Session
Session Title: Genitourinary Cancer—Prostate, Testicular, and Penile
Track: Genitourinary Cancer—Prostate, Testicular, and Penile
Abstract: LBA5000
Christos Kyriakopoulos, Yu-Hui Chen, Robert Jeraj, Fenghai Duan, Jun Luo, Emmanuel Antonarakis, Abhishek Tripathi, David Kosoff, Rohan Garje, Russell Pachynski, Rahul Parikh, Andrea Harzstark, Nabil Adra, Benjamin Maughan, Yousef Zakharia, Paul Corn, Glenn Liu, Michael CarducciJune 2, 2024
NeoTRACT: Phase II trial of neoadjuvant tumor infiltrating lymphocyte- and response-adapted chemoimmunotherapy for triple-negative breast cancer (TNBC).
9 am – 12 pm
Hall A | On Demand
Poster Session
Session Title: Breast Cancer – Local/Regional/Adjuvant
Track: Breast Cancer
Abstract: TPS629, Poster Bd #: 212a
Shane Stecklein, Allison Aripoli, Roberto Salgado, Anne O'Dea, Lauren Nye, Kelsey Larson, Deepti Satelli, Ryan Rader, Rashna Madan, Rachel Yoder, Joshua Staley, India Fernandez, Adam Heinrich, Jamie Wagner, Christa Balanoff, Lyndsey Kilgore, Leonidas Bantis, Andrew Godwin, Qamar Khan, Priyanka Sharma
NRG-BR007: A phase III trial evaluating de-escalation of breast radiation (DEBRA) following breast-conserving surgery of stage 1, HR+, HER2-, RS ≤18 breast cancer.
9 am – 12 pm
Hall A | On Demand
Poster Session
Session Title: Breast Cancer – Local/Regional/Adjuvant
Track: Breast Cancer
Abstract: TPS622, Poster Bd #: 208b
Julia White, Reena Cecchini, Eleanor Harris, Eleftherios Mamounas, Daniel Stover, Patricia Ganz, Reshma Jagsi, Stewart Anderson, Carmen Bergom, Valérie Théberge, Mahmoud El-Tamer, Richard Zellars, Dean Shumway, Guang-Pei Chen, Thomas Julian, Norman WolmarkIntensification of ADT with enzalutamide in high-risk patients with biochemical relapse following radical prostatectomy undergoing salvage radiation: Initial results from RTOG 3506 (STEEL).
9 am – 12 pm
Hall A | On Demand
Poster Session
Session Title: Genitourinary Cancer—Prostate, Testicular, and Penile
Track: Genitourinary Cancer—Prostate, Testicular, and Penile
Abstract: 5101, Poster Bd #: 507
Edwin Posadas, Hiram Gay, Joseph Rodgers, Todd Morgan, Ying Xiao, James Yu, Jeff Michalski, Myriam Bouchard, Neil Desai, Ryan Funk, Thomas Boike, Donald Jurgens, Anthony Wong, Xinglei Shen, Lloyd Miyawaki, Christopher Bland, John Hairston, Howard Sandler, Stephanie Pugh, Felix FengA pilot study of tazemetostat and pembrolizumab in advanced urothelial carcinoma (ETCTN 10183).
9 am – 12 pm
Hall A | On Demand
Poster Session
Session Title: Genitourinary Cancer—Kidney and Bladder
Track: Genitourinary Cancer—Kidney and Bladder
Abstract: 4574, Poster Bd #: 269
Maha Hussain, Masha Kocherginsky, Parminder Singh, Winston Tan, Zin Myint, Di (Maria) Jiang, Elizabeth Wulff-Burchfield, Yangruijue Ma, Elad Sharon, Richard Piekarz, Joshua Meeks, David VanderWeeleA phase 2 trial of ADT interruption in patients responding exceptionally to AR-pathway inhibitor in metastatic hormone-sensitive prostate cancer (A-DREAM/Alliance A032101).
9 am – 12 pm
Hall A | On Demand
Poster Session
Session Title: Genitourinary Cancer—Prostate, Testicular, and Penile
Track: Genitourinary Cancer—Prostate, Testicular, and Penile
Abstract: TPS5118, Poster Bd #: 518b
Atish Choudhury, Glenn Heller, Melissa Reimers, Andrew Laccetti, Fabrice Smieliauskas, Praful Ravi, Katharine Dooley, Gina Mazza, Benjamin Gartrell, Preston Steen, Kayla Kroll, Shiva Baghaie, Archana Ajmera, Thomas Smith, Himisha Beltran, Ronald Chen, Rana McKay, Matt Galsky, Jonathan Rosenberg, Michael MorrisA phase III trial evaluating addition of adjuvant chemotherapy to ovarian function suppression + endocrine therapy in premenopausal women with pN0-1, HR+/HER2- breast cancer (BC) and oncotype recurrence score (RS) ≤25 (OFSET): NRG-BR009.
9 am – 12 pm
Hall A | On Demand
Poster Session
Session Title: Breast Cancer—Local/Regional/Adjuvant
Track: Breast Cancer
Abstract: TPS612, Poster Bd #: 203b
Sandra Swain, Gong Tang, Shannon Puhalla, Patricia Ganz, Norah Henry, Reena Cecchini, Sonya Reid, Priya Rastogi, Charles Geyer, Julia White, Amy Clark, Tufia Haddad, Gregory Vidal, Norman Wolmark, Eleftherios Mamounas
9 am – 12 pm
Hall A | On Demand
Poster Session
Session Title: Breast Cancer—Local/Regional/Adjuvant
Track: Breast Cancer
Abstract: TPS613, Poster Bd #: 204a
Lior Braunstein, Melissa Mitchell, Hanna Bandos, William Sikov, Atif Khan, Peter Chen, Patricia Ganz, Reshma Jagsi, Julia White, Reena Cecchini, Hyejoo Kang, Shannon Puhalla, Kelly Bolton, Eileen Connolly, Erica Stringer-Reasor, Kimberly Gergelis, Thomas Julian, Eleftherios Mamounas, Norman WolmarkJune 3, 2024
Effects of immune-enhancing nutrition on radical cystectomy outcomes: Primary results from the randomized phase III double-blind clinical trial (S1600).
8 am – 11 am
Hall B1 | Live Stream
Oral Abstract Session
Session Title: Genitourinary Cancer—Kidney and Bladder
Track: Genitourinary Cancer—Kidney and Bladder
Abstract: 4501
Jill Hamilton-Reeves, Joseph Unger, Jeffrey Holzbeierlein, Danika Lew, James Ryan Mark, Siamak Daneshmand, Janet Kukreja, Eugene Lee, William Tabayoyong, Dawn Hershman, Michael Fisch, Norah Henry
Impact of late immune effector cell associated hematotoxicity (ICAHT) and prolonged neutropenia after CAR-T therapy on infection and survival outcomes.
9 am – 12 pm
Hall A | On Demand
Poster Session
Session Title: Hematologic Malignancies—Lymphoma and Chronic Lymphocytic Leukemia
Track: Hematologic Malignancies
Abstract: 7041, Poster Bd #: 24
Morgan Zenner, Spencer Lessans, Kai Rejeski, Miguel-Angel Perales, Richard Maziarz, Andy Chen, David Porter, Stephen Schuster, Joseph McGuirk, Michael Bishop, Veronika Bachanova, Loretta Nastoupil, Peter Riedell, Olalekan Oluwole, Shakthi Bhaskar, Vivek Patel
Phase 2 open label, multicenter study evaluating CRG-022, a CD22-directed autologous CAR T-cell therapy, in patients (pts) with relapsed/refractory (R/R) large B-cell lymphoma (LBCL) after CD19-directed CAR T-cell therapy.
9 am – 12 pm
Hall A | On Demand
Poster Session
Session Title: Hematologic Malignancies—Lymphoma and Chronic Lymphocytic Leukemia
Track: Hematologic Malignancies
Abstract: TPS7085, Poster Bd #: 67a
Armin Ghobadi, Caron Jacobson, Joseph McGuirk, Nirali Shah, John Rossi, Tonia Buchholz, Lizamarie Bachier-Rodriguez, John Baird, Catherine Diefenbach, Umar Farooq, Francisco Hernandez-Ilizaliturri, Iris Isufi, Krish Patel, Sattva Neelapu, Craig Sauter, Jay Spiegel, Michael Tees, John Timmerman, Ginna Laport, Matthew Frank
VERIFY: A randomized controlled phase 3 study of the hepcidin mimetic rusfertide (PTG-300) in patients with polycythemia vera (PV).
9 am – 12 pm
Hall A | On Demand
Poster Session
Session Title: Hematologic Malignancies—Leukemia, Myelodysplastic Syndromes, and Allotransplant
Track: Hematologic Malignancies
Abstract: TPS6592, Poster Bd #: 147b
Aniket Bankar, Kristen Pettit, Joseph Shatzel, Abdulraheem Yacoub, Naveen Pemmaraju, Harinder Gill, Antonin Hlusi, Alessandro Lucchesi, Samah Alimam, Jiří Mayer, Francesca Palandri, Daniel Sasca, Katharina Modelska, Suneel Gupta, Ifode Ajari, Sarita Khanna, Arturo Molina, Andrew Kuykendall
A first-in-human, phase 1, dose escalation study of SGR-2921 as monotherapy in patients with relapsed/refractory acute myeloid leukemia or myelodysplastic syndrome.
9 am – 12 pm
Hall A | On Demand
Poster Session
Session Title: Hematologic Malignancies—Leukemia, Myelodysplastic Syndromes, and Allotransplant
Track: Hematologic Malignancies
Abstract: TPS6590, Poster Bd #: 146b
Daniel Weiss, Courtney Dinardo, Stephen Strickland, Barry Skikne, Amer Zeidan, Elie Traer, Hetty Carraway, Stanley Frankel, Jacky Wang, Steven Pirie-Shepherd, Joseph Piccotti, Duncan Hamish Wright, Karen Akinsanya
Enfortumab vedotin (EV) in non-squamous and squamous non–small cell lung cancer (NSCLC) cohorts of EV-202.
1:30 pm – 4:30 pm
Hall A | On Demand
Poster Session
Session Title: Lung Cancer—Non-Small Cell Metastatic
Track: Lung Cancer
Abstract: 8585, Poster Bd #: 449
Kei Muro, Trevor Feinstein, Joaquina Baranda, Ioana Bonta, Satoru Kitazono, Todd Gersten, Leena Gandhi, Toshihiro Kudo, Jason Kaplan, Seema Gorla, Shubin Liu, Michele Wozniak, Anthony Lee, Tejas Patil
Young adults (YA) with non-small cell lung cancer (NSCLC): Snapshot of the oncogenic drivers and immune landscapes.
1:30 pm – 4:30 pm
Hall A | On Demand
Poster Session
Session Title: Lung Cancer—Non-Small Cell Metastatic
Track: Lung Cancer
Abstract: 8538, Poster Bd #: 402
Aaron Pruitt, Robert Hsu, Nishant Gandhi, Coral Olazapasti, Estelamari Rodriguez, Dwight Owen, Jinesh Gheeya, Jun Zhang, Muhammad Furqan, Jaclyn LoPiccolo, Andrew Elliott, Ari VanderWalde, Stephanie Rock, Patrick Ma, Balazs Halmos, Zhonglin Hao
Predictive models as a clinical decision support tool for genetic cancer risk assessment among Mexican patients at risk of hereditary colorectal cancer.
1:30 pm – 4:30 pm
Hall A | On Demand
Poster Session
Session Title: Prevention, Risk Reduction, and Genetics
Track: Prevention, Risk Reduction, and Genetics
Abstract: 10617, Poster Bd #: 144
Jose Luis Rodriguez Olivares, Dione Aguilar y Méndez, Pamela Rivero Garcia, Alejandro Aranda-Gutierrez, Rocío Ortiz-Lopez, Sandra Santuario Facio, Augusto Rojas-Martinez, Leticia Barraza, Jazmin Arteaga Vazquez, Hector De La Mora, Tamara N. Kimball, Joanne Jeter, Jeffrey Weitzel, Yanin Chavarri Guerra
Correlation of serum anti-Müllerian hormone (AMH) levels on identification of premenopausal patients (pts) with hormone receptor positive (HR+), HER2-negative, node-positive breast cancer most likely to benefit from adjuvant chemotherapy in SWOG S1007 (RxPONDER).
3 pm – 6 pm
Hall B1 | Live Stream
Oral Abstract Session
Session Title: Breast Cancer—Local/Regional/Adjuvant
Track: Breast Cancer
Abstract: 505
Kevin Kalinsky, William Barlow, Harsh Pathak, Julie Gralow, Kathy Albain, Daniel Hayes, Nancy Lin, Edith Perez, Lori Goldstein, Stephen Chia, Priya Rastogi, Anne Schott, Steven Shak, Debashish Tripathy, Gabriel Hortobagyi, Funda Meric-Bernstam, Priyanka Sharma, Lajos Pusztai, Alastair Thompson, Andrew Godwin
Development and validation of RSClin N+ tool for hormone receptor-positive (HR+), HER2-negative (HER2-), node-positive breast cancer.
3 pm – 6 pm
Hall B1 | Live Stream
Oral Abstract Session
Session Title: Breast Cancer—Local/Regional/Adjuvant
Track: Breast Cancer
Abstract: 508
Lajos Pusztai, Jess Hoag, Kathy Albain, William Barlow, Salomon Stemmer, Allison Meisner, Gabriel Hortobagyi, Steven Shak, Daniel Hayes, James Rae, Frederick Baehner, Priyanka Sharma, Kevin Kalinsky
Impact of extramedullary multiple myeloma on outcomes with idecabtagene vicleucel.
3 pm – 6 pm
Hall D1 | Live Stream
Oral Abstract Session
Session Title: Hematologic Malignancies—Plasma Cell Dyscrasia
Track: Hematologic Malignancies
Abstract: 7508
Saurabh Zanwar, Surbhi Sidana, Leyla Shune, Omar Alexis Castaneda Puglianini, Oren Pasvolsky, Rebecca Gonzalez, Danai Dima, Aimaz Afrough, James Davis, Megan Herr, Hamza Hashmi, Peter Forsberg, Douglas Sborov, Shambavi Richard, Jack Khouri, Yi Lin, Krina Patel, Shaji Kumar, Doris Hansen, Gurbakhash KaurJune 4, 2024
HB-200 arenavirus-based immunotherapy plus pembrolizumab as first-line treatment of patients with recurrent/metastatic HPV16-positive head and neck cancer: Updated results.
9:45 am – 12:45 pm
S100a | Live Stream
Oral Abstract Session
Session Title: Head and Neck Cancer
Track: Head and Neck Cancer
Abstract: 6005
Alan Ho, Lisle Nabell, Prakash Neupane, Marshall Posner, Emrullah Yilmaz, Jiaxin Niu, Abdul Rafeh Naqash, Alexander Pearson, Stuart Wong, Jorge Nieva, Douglas Laux, Deborah Wong, Zujun Li, Ari Rosenberg, Winston Wong, Xiaoping Qing, Corinne Iacobucci, Henning Lauterbach, Ilian Tchakov, David PfisterPublication Only
Neurocognitive testing to predict ICANS post-CAR T.
Publication Only
Session Title: Publication Only: Hematologic Malignancies—Lymphoma and Chronic Lymphocytic Leukemia
Track: Hematologic Malignancies
Abstract: e19003
William Wesson, Lauren Scott, Nahid Suleman, Shaun DeJarnette, Al-Ola Abdallah, Forat Lutfi, Sunil Abhyankar, Leyla Shune, Muhammad Umair Mushtaq, Anurag Singh, Haitham Abdelhakim, Joseph McGuirk, Muhammad Nashatizadeh, Elizabeth Muenks, Hannah Katz, Nausheen AhmedDuctal carcinoma in situ: Molecular and cellular basis of malignancy.
Publication Only
Session Title: Publication Only: Breast Cancer—Local/Regional/Adjuvant
Track: Breast Cancer
Abstract: e12582
Fariba Behbod, Emre Arslan, Qian Zhu, Yan Hong, Benjamin Strope, Jamie Wagner, Kelsey Larson, Timothy Fields, Allison Aripoli, Ashley Huppe, Onalisa Winblad, Christa Balanoff, Jessica Peterson, Molly Hill, Camron Smith, Eric Chang, Andrew Godwin, Seema Khan, Carol Fabian, Kunal RaiCharacterizing clinical trials for CAR T targeting solid tumors from 2018 to 2023: A systematic review.
Publication Only
Session Title: Publication Only: Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology
Track: Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology
Abstract: e15080
William Wesson, Fathima Shehnaz Ayoobkhan, Zahra Mahmoudjafari, Muhammad Umair Mushtaq, Al-Ola Abdallah, Weijing Sun, Faiz Anwer, Gary Doolittle, Joseph McGuirk, Raed Al-Rajabi, Joaquina Baranda, Nausheen AhmedKANSURVIVE: Testing a telementoring model for improving cancer survivorship care in rural practice.
Publication Only
Session Title: Publication Only: Care Delivery/Models of Care
Track: Care Delivery and Quality Care
Abstract: e13791
Jennifer Klemp, Catie Knight, Edward Ellerbeck, Christie Befort, Eve-Lynn Nelson, Anne O'Dea, Prabhakar Chalise, Dorothy Hughes, Allen GreinerOncologic outpatient specialty palliative care referral utilization: A single institution quality improvement project.
Publication Only
Session Title: Publication Only: Quality Care/Health Services Research
Track: Care Delivery and Quality Care
Abstract: e23205
Rubina Ratnaparkhi, Elaine Pope, Ian Cook, Melissa Javellana, Andrea Jewell, Christian Sinclair, Lori SpoozakTrends in survival in solid malignancies with synchronous brain metastases: A population-based study.
Publication Only
Session Title: Publication Only: Quality Care/Health Services Research
Track: Care Delivery and Quality Care
Abstract: e23299
Parth Sharma, Tayla Miller, Himil Mahadevia, Ifrah Fatima, Priyanka Sharma, An-Lin Cheng, Anuj ShresthaPreliminary results of atezolizumab and pirfenidone in non-small cell lung cancer.
Publication Only
Session Title: Publication Only: Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology
Track: Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology
Abstract: e15197
Chao Huang, Jo Wick, Takefumi KomiyaReal-world first-line treatment patterns and outcomes in patients with locally advanced or metastatic urothelial carcinoma in the United States.
Publication Only
Session Title: Publication Only: Quality Care/Health Services Research
Track: Care Delivery and Quality Care
Abstract: e23287
Ronald Chen, Lisa Mucha, David Nimke, Christopher Young, Hongbo Yang, Qing Liu, Alexandra Greatsinger, Adina Zhang, Phoebe Wright, Christina QuicquaroRacial disparities in the intervention trials in colon cancer.
Publication Only
Session Title: Publication Only: Care Delivery/Models of Care
Track: Care Delivery and Quality Care
Abstract: e13718
Abhinav Vyas, Dania Kaur, Saloni Savani, Moazzam Shahzad, Rohit Singh, Udit Yadav, Muhammad Umair Mushtaq, Akshee Batra
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Underline: KUCC Members
Underline & Bold: KUCC Members that PresentedApril 7, 2023
SESSION PO.CL01.05 - Spatial Proteomics and Transcriptomics
1:30 PM - 5:00 PM
1136 / 3 - Tumor genomic and transcriptomic profiling of patients (pts) with metastatic castration sensitive prostate cancer (mCSPC) who do versus do not achieve an optimal PSA response to androgen deprivation therapy intensification (ADTi)
V. Mathew Thomas, B. Chigarira, G. Gebrael, C. Chehade, A. Narang, N. Sayegh, N. Tripathi, Y. Jo, C. Tandar, A. Srivastava, R. Ji, E. Dal, G. Fortuna, H. Li, B. L. Maughan, U. Swami, N. Agarwal
SESSION PO.PR01.03 - Epidemiology
1:30 PM - 5:00 PM
769 / 5 - Incorporating a cross-ancestry polygenic risk score into a clinical model improved breast cancer risk prediction in women with pathogenic variants
P. Tshiaba, M. Sun, D. Ratman, J. N. Weitzel, P. Shah, M. Rabinowitz, A. Kumar, K. Im
SESSION PO.PS01.10 - Environmental and Occupational Risk Factors, Infection, and Aging
1:30 PM - 5:00 PM
844 / 17 - DNA methylation-derived immune cell profiles and risk of cancers in Black participants in the ARIC Study
C. S. Semancik, N. Zhao, D. Koestler, E. Boerwinkle, J. Bressler, K. Kelsey, E. A. Platz, D. S. Michaud
SESSION PO.TB04.04 - Membrane, Biophysical, and EMT Aspects of Motility/Metastasis
1:30 PM - 5:00 PM
197 / 6 - The GPR52-MCAM axis as a novel regulatory mechanism of breast cancer cell clustering and metastatic potential
S. Z. Hanif, C. C. Au, I. Torregroza, B. Bhinder, L. Dow, O. Elemento, T. Evans, K. A. Brown
SESSION PO.CL01.05 - Spatial Proteomics and Transcriptomics
1:30 PM - 5:00 PM
1163 / 30 - Increased spatial coupling of integrin and collagen IV in the immunoresistant clear cell renal cell carcinoma tumor microenvironment
A. C. Soupir, M. T. Hayes, T. C. Peak, O. E. Ospina1, N. H. Chakiryan, A. E. Berglund1, P. A. Stewart, J. Nguyen, C. M. Moran-Segura, N. L. Francis, P. M. Ramos-Echevarria, J. Chahoud, R. Li, K. Y. Tsai, J. A. Balasi, Y. Caraballo-Perez, J. Dhillon, L. A. Martinez, W. E. Gloria, N. Schurman, S. Kim, M. Gregory, J. J. Mule, B. L. Fridley, B. J. Manley
SESSION PO.TB06.01 - Developmental Origins and Drivers of Pediatric Cancer
1:30 PM - 5:00 PM
141 / 13 - A human induced pluripotent stem cell model of KMT2A rearranged leukemia
E. Guest, M. Vacek, J. Nemechek, I. Pushel, B. T. Thornton, M. Leyda, M. S. Farooqi, J. M. Perry, J. L. Vivian
SESSION PO.BCS01.01 - Application of Bioinformatics to Cancer Biology 1
1:30 PM – 5:00 PM
876 / 20 - spatialGE: Empowering researchers to study the tumor microenvironment leveraging spatial transcriptomics
O. Ospina, R. Manjarres-Betancur, G. Gonzalez-Calderon, A. C. Soupir, I. Smalley, K. Tsai, J. Markowitz, A. Berglund, X. Yu, B. L. Fridley
SESSION MS.TB04.01 - Metastasis
3:00 PM - 5:00 PM
Room 29 - Upper Level - Convention Center
Track(s): Tumor Biology, Tumor Microenvironment
Introduction; Chairperson, Danny R. Welch, University of Kansas Cancer Center, Kansas City, KSApril 8, 2024
SESSION PO.BCS01.12 - New Algorithms, Software, and Models
9:00 AM - 12:30 PM
2338 / 16 - Benchmarking long- and short-read somatic structural variation callers using a multi-technology panel of six tumor/normal cell lines
A. Keskus, A. Bryant1, T. Ahmad, A. Donmez, I. Rodriguez, N. Rossi, Y. Xie, B. Yoo, R. Milano, H. Lou, J. Park, J. Gardner, B. McNulty, K. Miga, M. Dean, M. Farooqi, B. Paten, M. Kolmogorov
SESSION PO.IM01.02 - Immune Checkpoints and Inhibitory Molecules 1
9:00 AM - 12:30 PM
1352 / 3 - Computational design of a cyclic peptide that inhibits the CTLA4 in T cells and the growth of lung carcinoma in mice
R. Thakkar, D. Upreti, S. Ishiguro, G. Magnin, K. Sudasinghe, A. Hall, S. DeVader, M. Tamura, J. Comer
SESSION PO.IM02.03 - Inflammation and Cancer in Metastasis
9:00 AM - 12:30 PM
1399 / 19 - The role of CCN5 in regulation of tumor-infiltrating lymphocytes (TILS) in triple-negative breast cancer (TNBC) cells
U. Biswas, A. Kambhampati, N. Haideri, A. De, S. Upadhyay, S. Banerjee, S. Banerjee
SESSION PO.MCB03.01 - Cell Signaling Components as Therapeutic Targets
9:00 AM - 12:30 PM
1667 / 14 - The role of CCN1 in mutant K-RAS addiction in pancreatic cancer
A. Kambhampati, A. De, I. Haque, S. Banerjee, S. K. Banerjee
SESSION PO.ET09.06 - Novel Targets and Pathways
9:00 AM - 12:30 PM
Section 29
2086 / 10 - Effect of XPO1 inhibition on colorectal cancer tumorigenesis
A. E. Evans, D. A. Dixon
SESSION PO.MCB08.02 - Genomic Characterization of Cancers and Cancer Subgroups
9:00 AM - 12:30 PM
1763 / 18 - Long-read sequencing of pediatric leukemia identifies clinically relevant genomic rearrangements
B. Yoo, A. Keskus, C. Bi, L. Lansdon, T. Ahmad, I. Pushel, A. Walter, M. Gibson, E. Guest, T. Pastinen, M. Kolmogorov, M. S. Farooqi
SESSION PO.MCB09.02 - Metabolic Pathways 2
9:00 AM - 12:30 PM
1783 / 5 - Understanding lipogenesis in bladder cancer
J. Leak, D. Matye, E. Abbott, B. Woolbright, J. A. Taylor III
1785 / 7 - The role of BRCA1 on metabolic pathways in an in vivo system
S. L. Hembruff, A. Dekonenko, J. Thyfault, M. Sardiu, M. Washburn, R. A. Jensen, L. M. Harlan-Williams
SESSION PO.PR02.01 - Role of Diet, Nutrition, and the Microbiome Across the Cancer Continuum
9:00 AM - 12:30 PM
2187 / 21 - Influences of high-fat diet on tumor biology in a mouse model of colorectal cancer
A. Mahanty, C. Wallingford, R. Hammontree, M. Njoka, Z. Clark, M. Rekowski, M. Washburn, J. S. Davis
SESSION PO.BCS01.03 - Application of Bioinformatics to Cancer Biology 3
1:30 PM - 5:00 PM
3497 / 19 - Glioma Immune Microenvironment Composition Calculator (GIMiCC): A method of estimating the proportions of eighteen key cell types from human brain tissue assayed using Illumina DNA methylation microarray technology
S. C. Pike, J. K. Wiencke, Z. Zhang, A. M. Molinaro, D. C. Koestler, B. C. Christensen, K. T. Kelsey, L. A. Salas
SESSION PO.BCS01.09 - Database Resources, Statistical Methods, and Other Tools
1:30 PM - 5:00 PM
3562 / 22 - Comparison of spatial co-localization measures for studying the tumor immune microenvironment with application to ovarian cancer
B. L. Fridley, A. Soupir, J. Wrobel, C. Colin-Leitzinger, M. K. Townsend, A. B. Lawson, K. L. Terry, J. M. Schildkraut, S. S. Tworoger, L. C. Peres
SESSION PO.CL01.03 - Circulating Tumor Cells 1
1:30 PM - 5:00 PM
3707 / 19 - Characterization of estrogen receptor expression on CTCs during CDK4/6i treatment in HR+/HER2- metastatic breast cancer: Results from the PACE phase II study
M. S. Serafini, C. Reduzzi, L. Gerratana, R. Jeselsohn, R. L. Mahtani, C. X. Ma, A. DeMichele, J. L. Meisel, K. D. Miller, Y. Abdou, E. C. Riley, R. Qamar, P. Sharma, S. Reid, H. J. Burstein, S. M. Tolaney, M. K. DeMeo, Y. Liu, E. Gauthier, Y. Ren, M. M. Regan, H. Liu, E. L. Mayer, M. Cristofanilli
SESSION PO.ET02.03 - Cancer Immunotherapy and Drug Delivery
1:30 PM - 5:00 PM
3185 / 2 - Glatiramer acetate enhances tumor retention and mitigates systemic toxicity of toll-like receptor 9 agonists as intratumoral immunotherapy
H. Gong, D. J. Griffin, C. E. Groer, X. Wu, M. M. Abdelaziz, S. Wu, L. Xu, L. M. Forrest, C. J. Berkland
SESSION PO.MCB10.02 - microRNA- and Other Non-coding RNA-Based Translational Medicine
1:30 PM - 5:00 PM
2998 / 15 - Regulation of epidermal growth factor receptor signaling by BRCA1-microRNA 146a network
E. Kumaraswamy, R. M. Koren Shimak, S. Gunewardena, K. L. Wendt, D. Alexander, S. L. Hembruff, R. A. Jensen
SESSION PO.PS01.07 - Biomarkers of Endogenous or Exogenous Exposures, Early Detection, Biologic Effects, and Prognosis
1:30 PM - 5:00 PM
3424 / 8 - Assessing a DNA methylation-based telomere length estimator in individuals with a heavy smoking history
L. Grieshober, S. Graw, M. J. Barnett, G. E. Goodman, C. Chen, D. C. Koestler, C. J. Marsit, J. A. Doherty
SESSION MS.MCB08.01 - Advances in Cancer Genomics: Carcinogenesis, Tumor Evolution, and Hetero
2:35 PM – 2:50 PM
3928 - Genomic landscape and estimation of immune infiltration of soft tissue sarcoma histology subtypes from the ORIEN network
A. C. Soupir, O. E. Ospina, D. Hedges, J. K. Teer, M. D. Radmacher, D. M. McKean, N. Seligson, M. McCarter, B. Wilkey, G. Riedlinger, J. Groundland, B. J. Miller, B. Schneider, R. Patel, A. Rafeh-Naqash, S. Edge, B. Salhia, C. Moskaluk, M. Johns, M. L. Churchman, O. Hampton, D. Liebner, B. L. Fridley, A. S. BrohlApril 9, 2024
SESSION LBPO.MCB02 - Late-Breaking Research: Molecular/Cellular Biology and Genetics 29:00 AM - 12:30 PM
LB303 / 19 - Suppression of stress granule formation is a novel vulnerability imposed by mutant p53
E. Thoenen, A. Ranjan, A. Parrales, S. Nishikawa, D. Dixon, S. Oka, T. Iwakuma
SESSION PO.CL01.02 - Prognostic Biomarkers 1
9:00 AM - 12:30 PM
5215 / 23 - Orphan noncoding RNA (oncRNA) liquid biopsy assay is prognostic for survival in patients with triple-negative breast cancer (TNBC) and residual disease
R. Yoder, J. Yen, M. Karimzadeh, J. M. Staley, I. Fernandez, A. C. Heinrich, F. Hormozdiari, J. Gregg, A. K. Godwin, I. Acerbi, R. Trivedi, B. Alipanahi, S. R. Stecklein, P. Sharma
SESSION PO.CL13.01 - Molecular Biology in Clinical Oncology: Genetics and Beyond
9:00 AM - 12:30 PM
5060 / 14 - Role of molecular driver mutations in recurrence of early stage laryngeal cancer following narrow field definitive radiotherapy
A. Segura, E. Nissen, C. Lominska, R. Morse, D. Morgan, P. Neupane, D. Pei, D. Koestler, R. Kimple, U. Duvvuri, K. Sykes, S. Thomas, R. Nallani, L. Shnayder, K. Kakarala, E. Yilmaz, A. Bur
SESSION PO.IM02.01 - Adaptive Immunity in Tumors
2024, 9:00 AM - 12:30 PM
3971 / 13 - Progesterone impacts regulatory T cell activity to promote immunosuppression in the mammary gland
E. I. Chowanec, L. R. Werner, C. R. Hagan
3981 / 23 - Immune targeting progesterone receptor in hormone receptor positive breast cancer
A. E. Wilson, J. Wei, G. Lei, X.-Y. Yang, C.-X. Liu, M. Gajda, T. Wang, C. Hagan, Z. C. Hartman
SESSION PO.MCB09.05 - Signaling Pathways That Regulate Metabolism 2
9:00 AM - 12:30 PM
4460 / 14 - Investigating a non-canonical role for SHP2 in pancreatic ductal adenocarcinoma metabolism and response to dietary modifications
R. Walsh, J. L. Jack, A. E. Eades, B. A. Bye, M. T. Ruckert, J. Ambrose, M. N. VanSaun
SESSION LBPO.PR01 - Late-Breaking Research: Prevention, Early Detection, and Interception
1:30 PM - 5:00 PM
LB381 / 12 - Plasma microbiota as novel biomarkers of early epithelial ovarian cancer detection
D. E. Mahoney, P. Chalise, D. Pei, R. Griffard, T. Home, H. Pathak, S. Umar, A. K. Godwin
SESSION PO.CL01.10 - Predictive Biomarkers 5
1:30 PM - 5:00 PM
6417 / 29 - Urinary PKM2 in muscle invasive bladder cancer
D. Matye, J. Leak, E. Abbott, B. Woolbright, J. Taylor III
SESSION PO.CTP02.01 - Phase II and Phase III Clinical Trials in Progress
1:30 PM - 5:00 PM
CT286 / 16 - TILVANCE-301, a phase 3 study of lifileucel tumor-infiltrating lymphocyte (TIL) cell therapy in combination with pembrolizumab vs pembrolizumab alone in treatment-naive unresectable or metastatic melanoma
S. Thomas, Y. K. Hong, Y. Samhouri, J. Larkin, D. J. Olson, G. K. In, V. Atkinson, P. Lammers, A. J. S. Furness, J. Martin-Liberal, P. Terheyden, A. S. Poklepovic, R. H. Nguyen, I. Peretz, M. Butler, A. Khattak, L. Spain, E. Gaughan, M. Wilson, J. W. Dubay, A. Williams, S. Goff, G. C. Doolittle, J. Chesney, F. Finckenstein, J. Chou, X. Wu, G. Sulur, W. Shi, J. Haanen
SESSION PO.IM02.08 - Tumor-Induced Immune Suppression 2: Intrinsic Factors
1:30 PM - 5:00 PM
5364 / 15 - Progesterone receptor modulates the antigen processing and presentation machinery decreasing MHC class I expression on tumors
J. Tinoco, L. Werner, E. Chowanec, H. Saunders, S. Xiaopeng, J. Gertz, J. Balko, Z. C. Hartman, C. Hagan
SESSION PO.MCB11.02 - Advances in Cancer Prognostication, Therapeutic Response, and Immune Biology
1:30 PM - 5:00 PM
5596 / 20 - Exploring BRCA1-Y1853ter and potential therapeutic targets in BRCA1-BRCT mutated cancers
J. Chen
SESSION PO.TB11.06 - Tumor-Immune System Cross-Talk
1:30 PM - 5:00 PM
5557 / 13 - Stem-like T cells maintain latent anticancer activity and underly therapy resistance
F. Tao, S. McElroy, J. Nemechek, I. Pushel, J. Szarejko, S. Khanal, T. Bradley, D. Myers, J. M. Perry
SESSION MS.EN01.01 - Molecular, Preclinical, and Clinical Endocrinology 3
2:35 PM - 2:50 PM
Room 5 - Upper Level - Convention Center
6571 - O-GlcNAc sites on progesterone receptor are critical for its ligand independent repression of interferon signaling in breast cancer
H. I. Saunders, S. Holloran, E. Chowanec, J. Tinoco, C. Slawson, C. Hagan
April 10, 2024
SESSION PO.TB11.04 - Chemokines and Cytokines in Cancer
9:00 AM - 12:30 PM
6803 / 8 - TRIM16 regulates IL-6 secretion in head and neck cancer-associated fibroblasts
T. Ly, B. Pickard, A. Pandey, N. Martinez-Rivera, E. Rosa-Molinar, M. Washburn, W.-X. Ding, S. M. Thomas
SESSION PO.TB11.09 - Immune Cells in the Tumor Microenvironment 2
9:00 AM - 12:30 PM
6877 / 21 - Progesterone promotes immunosuppression in the murine mammary gland by causing T cell death
A. Heard, L. R. Werner, E. I. Chowanec, H. Saunders, J. Tinoco, Z. C. Hartman, C. R. Hagan
6885 / 29 - Investigating a novel role of DCLK1 isoforms in colitis and colitis associated colon cancer
K. A. Yusuf, B. C. Roy, S. Anant, S. Umar -
December 9, 2023
121 The Methylome Atlas of Acute Leukemia Enables Novel Clinical Diagnostic Tool for AML
Session: 803. Emerging Tools, Techniques and Artificial Intelligence in Hematology: Reading the Blood: Generative and Discriminative AI in Hematology
Program: Oral and Poster Abstracts
Type: Oral
Time: 9:30 AM
Location: San Diego Ballroom AB (Marriott Marquis San Diego Marina)Francisco Marchi, Marieke Landwehr, Fernando Sckaff, Xueyuan Cao, PhD, Raul C. Ribeiro, MD, Jeffrey E. Rubnitz, MD, PhD, Alan S Gamis, MD, MPH, E. Anders Kolb, MD, Richard Aplenc, MD, PhD, Stanley Pounds, PhD, Todd A. Alonzo, PhD, Soheil Meshinchi, MD, PhD and Jatinder K. Lamba, PhD
91 Real-World Safety and Efficacy of Teclistamab for Patients with Heavily Pretreated Relapsed-Refractory Multiple Myeloma
Session: 652. Multiple Myeloma: Clinical and Epidemiological: T Cell Redirecting Therapy Outcomes and Associated Complications Clinically Relevant Abstract
Program: Oral and Poster Abstracts
Type: Oral
Time: 9:30 AM
Location: Seaport Ballroom ABCD (Manchester Grand Hyatt San Diego)Danai Dima, MD, James A Davis, PharmD, Nausheen Ahmed, MD, Aishwarya Sannareddy, MBB, Hira Shaikh, MBB, Zahra Mahmoudjafari, PharmD, Jack Khouri, MD, Gurbakhash Kaur, MD, Christopher Strouse, Jason Valent, Larry D. Anderson Jr., MD, PhD, Faiz Anwer, MD, Al-Ola Abdallah, MD and Hamza Hashmi, MD
107 Real-World Outcomes of Brexucabtagene Autoleucel (Brexu-cel) for Relapsed or Refractory (R/R) Mantle Cell Lymphoma (MCL): A CIBMTR Subgroup Analysis of High-Risk Characteristics
Session: 705. Cellular Immunotherapies: Late Phase and Commercially Available Therapies: Cellular Therapy for B Cell Lymphomas: Prospective Clinical Trials and Real-World Data
Program: Oral and Poster Abstracts
Type: Oral
Time: 10:30 AM
Location: Room 6A (San Diego Convention Center)Swetha Kambhampati, MD, Nausheen Ahmed, MD, Mehdi Hamadani, MD, Soyoung Kim, PhD, Michael T. Hemmer, MS, Natalie S. Grover, MD, Mazyar Shadman, MD, MPH, Amer Beitinjaneh, MD, MPH, MSc, Elizabeth Lihua Budde, MD, PhD, James Gerson, MD, Caron A Jacobson, MD, MMSc, Frederick L. Locke, MD, Dwivedy S. Nasta, MD, Michael L. Wang, MD, Wen-Kai Weng, MD, PhD, Jiali Yan, MS, Ana Nunes, PharmD, David Dalton, PharmD, James J. Wu, MPH, MSc, Amina Abdeldaim, MD, MPH, Zhen-Huan Hu, MPH, Marcelo Pasquini, MD, MS and Alex F. Herrera, MD
137 Real-World Analysis of Thromboembolic Event Rates in Patients in the United States with Polycythemia Vera
Session: 904. Outcomes Research – Non-Malignant Conditions: Across the Age Spectrum: Thromboembolism Outcomes in Adult and Pediatric Patients
Program: Oral and Poster Abstracts
Type: Oral
Time: 10:30 AM
Location: Pacific Ballroom Salons 18-19 (Marriott Marquis San Diego Marina)Andrew T. Kuykendall, MD, Abdulraheem Yacoub, MD, Nancy Reaven, Susan Funk, Pedro Oyuela, MD, Frank Valone, MD, Phil Dinh, Lucy Bellamy, Nikita Modi, PharmD, Arturo Molina, MD, MS, FACP and Suneel Gupta, PhD
355 Predictors of Cytokine Release Syndrome and Neurotoxicity in Patients with Large B-Cell Lymphoma and Their Impact on Survival
Session: 705. Cellular Immunotherapies: Late Phase and Commercially Available Therapies: Prediction and Management of CAR-T Cell Related Toxicity Clinically Relevant Abstract
Program: Oral and Poster Abstracts
Type: Oral
Time: 4 PM
Location: Room 6B (San Diego Convention Center)Roni Shouval, MD, PhD, Christopher Strouse, MD, Soyoung Kim, PhD, Temitope Oloyede, MPH, Sairah Ahmed, MD, Farrukh T. Awan, MD, Veronika Bachanova, MD, PhD, Talha Badar, MD, Pere Barba, MD, Amer M. Beitinjaneh, MD, MS, Amanda F Cashen, Bhagirathbhai Dholaria, MBBS, Mahmoud Elsawy, MD, MSc, Siddhartha Ganguly, MD, Praveen Ramakrishnan Geethakumari, MD, MS, Uri Greenbaum, MD, Hamza Hashmi, MD, Laquisa C. Hill, BS, MD, Michael D. Jain, MD, PhD, Tania Jain, MD, Partow Kebriaei, MD, Adam S Kittai, MD, Frederick L. Locke, MD, Premal D. Lulla, MBBS, Elena Mead, MD, Joseph P McGuirk, DO, Alberto Mussetti, Taiga Nishihori, MD, Amanda L. Olson, MD, Martina Pennisi, Miguel-Angel Perales, MD, Peter A. Riedell, MD, Wael Saber, MD, MS, Sayeef Mirza, MD, MPH, Margarida Magalhaes-Silverman, MD, Elizabeth J. Shpall, MD, Mohamed Sorror, MD, MSc, Kitsada Wudhikarn, MD, Cameron J. Turtle, MBBS, PhD, Marcelo Pasquini, MD, MS and Amy Moskop, MD
1535 A Randomized Phase 2 Trial of 28-Day (Arm A) Versus 14-Day (Arm B) Schedule of Venetoclax + Azacitidine in Newly Diagnosed Acute Myeloid Leukemia Patients ≥ 60 Years
Session: 615. Acute Myeloid Leukemias: Commercially Available Therapies, Excluding Transplantation and Cellular Immunotherapies: Poster I
Program: Oral and Poster Abstracts
Type: Poster
Time: 5:30 PM
Location: Halls G-H (San Diego Convention Center)Uma M. Borate, MBBS, MS, Ying Huang, MS, MA, Mary F. Johnson, PhD, Joshua F. Zeidner, MD, Ronan T. Swords, MD, PhD, FRCP, FRCPath, Kristin L Koenig, MD, Eytan M. Stein, Maria R. Baer, MD, Wendy Stock, MD, Yazan F. Madanat, MD, Rebecca Olin, MD MSCE, William Blum, MD, Gary J. Schiller, MD, Tara L Lin, MD, Robert L. Redner, MD, Emily K Curran, MD, Nyla A. Heerema, PhD, Molly Martycz, Leonard Rosenberg, Sonja Gullen Marcus, MPH, Timothy Chen, PhD, Mona Stefanos, MD, Ross L Levine, MD, Brian J. Druker, MD, Ashley Owen Yocum, PhD, Amy Burd, PhD, Alice Mims, MD and John C. Byrd, MD
2159 131I-Apamistamab Effectively Achieved Durable Responses in Patients with R/R AML Irrespective of the Presence of Multiple High-Risk Factors
Session: 721. Allogeneic Transplantation: Conditioning Regimens, Engraftment and Acute Toxicities: Poster I
Program: Oral and Poster Abstracts
Type: Poster
Time: 5:30 PM
Location: Halls G-H (San Diego Convention Center)Stuart Seropian, MD, James M. Foran, MD, Boglarka Gyurkocza, MD, Rajneesh Nath, Hannah Choe, MD, Mark R. Litzow, MD, Nebu Koshy, MD, Patrick J. Stiff, MD, Ben K. Tomlinson, MD, Sunil Abhyankar, MD, Sameem Abedin, MD, George Chen, MD, Zaid Al-Kadhimi, MD, Partow Kebriaei, MD, Mitchell Sabloff, MSc, MD, FRCPC, Johnnie J. Orozco, MD, PhD, Katarzyna Joanna Jamieson, MD, Margarida Magalhaes-Silverman, MD, Koen Van Besien, MD, PhD, Michael W. Schuster, MD, Arjun D. Law, MD, Sebastian A. Mayer, MD, Hillard M. Lazarus, MD, Jennifer Spross, Kate L Li, PhD, Elaina Haeuber, MS, Madhuri Vusirikala, Akash Nahar, MD, MPH, Brenda M. Sandmaier, MD, John Pagel, MD, PhD, Sergio A. Giralt, MD, FACP, Avinash Desai, M.D and Camille N. Abboud, MD
2433 Progression to Myelofibrosis in Patients with Essential Thrombocythemia: A Real-World Analysis from the Prospective MOST Study
Session: 906. Outcomes Research – Myeloid Malignancies: Poster I
Program: Oral and Poster Abstracts
Type: Poster
Time: 5:30 PM
Location: Halls G-H (San Diego Convention Center)Stuart Seropian, MD, James M. Foran, MD, Boglarka Gyurkocza, MD, Rajneesh Nath, Hannah Choe, MD, Mark R. Litzow, MD, Nebu Koshy, MD, Patrick J. Stiff, MD, Ben K. Tomlinson, MD, Sunil Abhyankar, MD, Sameem Abedin, MD, George Chen, MD, Zaid Al-Kadhimi, MD, Partow Kebriaei, MD, Mitchell Sabloff, MSc, MD, FRCPC, Johnnie J. Orozco, MD, PhD, Katarzyna Joanna Jamieson, MD, Margarida Magalhaes-Silverman, MD, Koen Van Besien, MD, PhD, Michael W. Schuster, MD, Arjun D. Law, MD, Sebastian A. Mayer, MD, Hillard M. Lazarus, MD, Jennifer Spross, Kate L Li, PhD, Elaina Haeuber, MS, Madhuri Vusirikala, Akash Nahar, MD, MPH, Brenda M. Sandmaier, MD, John Pagel, MD, PhD, Sergio A. Giralt, MD, FACP, Avinash Desai, M.D and Camille N. Abboud, MD
2121 Comparative Effectiveness of Axicabtagene Ciloleucel Vs Historical Standard-of-Care in Patients with Relapsed or Refractory Follicular Lymphoma: An Analysis of CIBMTR and SCHOLAR-5 Data
Session: 705. Cellular Immunotherapies: Late Phase and Commercially Available Therapies: Poster I
Program: Oral and Poster Abstracts
Type: Poster
Time: 5:30 PM
Location: Halls G-H (San Diego Convention Center)Swetha Kambhampati, MD, Hai-Lin Wang, MPH, Jiali Yan, MS, Alex F. Herrera, MD, Matthew J. Frank, MD, PhD, Leslie L. Popplewell, MD, FACP, MPH, Nausheen Ahmed, MD, Yi Lin, MD, PhD, Frederick L. Locke, MD, Paola Ghione, MD, MSEpi, John G. Gribben, MD, DSc, Timothy Best, Christine Fu, PhD, Sara Beygi, MD, Markqayne D Ray, PharmD, John Bian, PhD, Zhen-Huan Hu, MPH, Fang Sun, MD, PhD, Marcelo Pasquini, MD, MS and Caron A Jacobson, MD, MMSc
1969 Outcomes of Patients with Relapsed/Refractory Multiple Myeloma Who Received at Least 2 BCMA-Directed Therapies
Session: 652. Multiple Myeloma: Clinical and Epidemiological: Poster I
Program: Oral and Poster Abstracts
Type: Poster
Time: 5:30 PM
Location: Halls G-H (San Diego Convention Center)Jordan Snyder, PharmD, Zain Alsaddi, Omar Alkharabsheh, MBBS, Barry Paul, Forat Lutfi, MD, Nausheen Ahmed, MD, Zahra Mahmoudjafari, PharmD, Al-Ola Abdallah, MD and Shebli Atrash, MD
1971 Outcomes of Vdpace for Relapsed/Refractory Multiple Myeloma in the Era of Daratumumab Based Therapy
Session: 652. Multiple Myeloma: Clinical and Epidemiological: Poster I
Program: Oral and Poster Abstracts
Type: Poster
Time: 5:30 PM
Location: Halls G-H (San Diego Convention Center)Priyanka Venkatesh, MBBS, Ghena Khasawneh, MD, Hamza Hashmi, MD, Omar Alkharabsheh, MD, Barry Paul, Barry S. Skikne, MD, Zahra Mahmoudjafari, PharmD, Nausheen Ahmed, MD, Al-Ola Abdallah, MD and Shebli Atrash, MD
1985 Efficacy of Daratumumab-Based Regimens in Anti-CD38 Treatment-Naïve Relapsed/Refractory Multiple Myeloma with High-Risk Cytogenetics, Clinically Relevant Abstract
Session: 652. Multiple Myeloma: Clinical and Epidemiological: Poster I
Program: Oral and Poster Abstracts
Type: Poster
Time: 5:30 PM
Location: Halls G-H (San Diego Convention Center)Jordan Snyder, PharmD, Razan Mansour, Aytaj Mammadzadeh, Hamza Hashmi, MD, Aimaz Afrough, MD, Omar Alkharabsheh, MBBS, Barry Paul, Shebli Atrash, MD, Muhammad Umair Mushtaq, MD, Barry S. Skikne, MD, Nausheen Ahmed, MD and Al-Ola Abdallah, MD
2344 The Glass Wall: Gendered Authorship Disparities in in CD 19 and BCMA CAR-T Clinical Trials for Lymphoma and Myeloma
Session: 902. Health Services and Quality Improvement – Lymphoid Malignancies: Poster I
Program: Oral and Poster Abstracts
Type: Poster
Time: 5:30 PM
Location: Halls G-H (San Diego Convention Center)Aroog Khaliq, William Wesson, MPH, Emerson Logan, Carine Tabak, Aliya Rashid, DO, MPH, Razan Mansour, Muhammad Umair Mushtaq, MD, Joseph P McGuirk, DO, Hamza Hashmi, MD, Mehdi Hamadani, MD, Al-Ola Abdallah, MD and Nausheen Ahmed, MD
1614 Single-Cell RNA Sequencing Facilitates Study of Cancer Mechanisms across Pediatric Leukemias
Session: 618. Acute Lymphoblastic Leukemias: Biomarkers, Molecular Markers and Minimal Residual Disease in Diagnosis and Prognosis: Poster I
Program: Oral and Poster Abstracts
Type: Poster
Time: 5:30 PM
Location: Halls G-H (San Diego Convention Center)Irina Pushel, PhD, Byunggil Yoo, MS, Daniel Louiselle, MS, Margaret Gibson, MB(ASCP), Alan S Gamis, MD, MPH, Keith J. August, MD, MS, Terrie Flatt, DO, MA, Tomi Pastinen, MD, PhD, Erin M. Guest, MD and Midhat S Farooqi, MD, PhD
2242 Outcomes after Bone Marrow Versus Peripheral Blood Haploidentical Hematopoietic Stem Cell Transplantation Using Post-Transplant Cyclophosphamide-Based Gvhd Prophylaxis
Session: 732. Allogeneic Transplantation: Disease Response and Comparative Treatment Studies: Poster I
Program: Oral and Poster Abstracts
Type: Poster
Time: 5:30 PM
Location: Halls G-H (San Diego Convention Center)Muhammad Kashif Amin, MD, Moazzam Shahzad, MD, Joe S. Al-Ramahi, Shaun DeJarnette, Forat Lutfi, MD, Nausheen Ahmed, MD, Haitham Abdelhakim, MD, Rajat Bansal, MD, Leyla Shune, MD, Al-Ola Abdallah, MD, Anurag K. Singh, MD, Sunil Abhyankar, MD, Joseph P McGuirk, DO and Muhammad Umair Mushtaq, MD
1558 Leveraging Custom CRISPR/Cas9 Screens to Identify AraC-Daunorubicin-Etoposide (ADE), Gemtuzumab Ozogamicin (GO), and Bortezomib Response Modulators Association with Clinical Outcomes in Pediatric AML
Session: 617. Acute Myeloid Leukemias: Biomarkers, Molecular Markers and Minimal Residual Disease in Diagnosis and Prognosis: Poster I
Program: Oral and Poster Abstracts
Type: Poster
Time: 5:30 PM
Location: Halls G-H (San Diego Convention Center)Nam Nguyen, MS, PharmD, Phani Krishna Parcha, PhD, Abderrahmane Tagmount, PhD, Bailey Gregory, Jeffrey E. Rubnitz, MD, PhD, Raul C. Ribeiro, MD, Xueyuan Cao, PhD, Todd A. Alonzo, PhD, Richard Aplenc, MD, PhD, Alan S Gamis, MD, MPH, Todd Cooper, DO, E. Anders Kolb, MD, Soheil Meshinchi, MD, PhD, Stanley Pounds, PhD, Christopher Vulpe, MD, PhD and Jatinder K. Lamba, PhD
981 Pirtobrutinib in Relapsed/Refractory (R/R) Mantle Cell Lymphoma (MCL) Patients with Prior cBTKi: Safety and Efficacy Including High-Risk Subgroup Analyses from the Phase 1/2 BRUIN Study
Session: 623. Mantle Cell, Follicular, and Other Indolent B Cell Lymphomas: Clinical and Epidemiological: Poster I
Program: Oral and Poster Abstracts
Type: Poster
Time: 5:30 PM
Location: Halls G-H (San Diego Convention Center)Krish Patel, MD, Julie M. Vose, MD, MBA, Sunita D. Nasta, MD, FACP, Jennifer R. Brown, MD, PhD, Kami J. Maddocks, MD, Jennifer A. Woyach, MD, Nirav N. Shah, MD, Bita Fakhri, MD, MPH, Benoit Tessoulin, Shuo Ma, MD, PhD, Deepa Jagadeesh, MD, Ewa Lech-Maranda, MD, PhD, Catherine C. Coombs, MD, Manish Patel, MD, Joanna M. Rhodes, MD, Chaitra S Ujjani, MD, Marc Hoffmann, MD, Chan Y Cheah, MBBS, FRACP, FRCPA, DMSc, Talha Munir, MBBS, MRCP, FRCPath, PhD, David Lewis, MBChB, PHD, Lydia Scarfo, MD, Toby A. Eyre, Alvaro J. Alencar, MD, Jonathon B. Cohen, MD, MS, Andrew D. Zelenetz, MD, PhD, Donald E. Tsai, MD, PhD, Mei Li, MS, Faith Bian, PhD, Paolo Abada, MD and Pier Luigi Zinzani, MD, PhD
1737 Pirtobrutinib in Richter Transformation: Updated Efficacy and Safety Results with 18-Month Median Survival Follow-up from the Phase 1/2 BRUIN Study, Clinically Relevant Abstract
Session: 626. Aggressive Lymphomas: Prospective Therapeutic Trials: Poster I Clinically Relevant Abstract
Program: Oral and Poster Abstracts
Type: Poster
Time: 5:30 PM
Location: Halls G-H (San Diego Convention Center)William G. Wierda, MD, PhD, Nirav N. Shah, MD, Chan Yoon Cheah, MD, David Lewis, MBChB, PHD, Marc Hoffmann, MD, Catherine C. Coombs, MD, Nicole Lamanna, MD, Shuo Ma, MD, PhD, Deepa Jagadeesh, MD, Talha Munir, MBBS, MRCP, FRCPath, PhD, Yucai Wang, MD, PhD, Toby A. Eyre, Joanna M. Rhodes, MD, Matthew McKinney, MD, Ewa Lech-Maranda, MD, PhD, Constantine S. Tam, MD, MBBS, Wojciech Jurczak, MD, PhD, Koji Izutsu, MD, PhD, Alvaro J. Alencar, MD, Manish Patel, MD, John F. Seymour, MBBS, PhD, FRACP, Jennifer A. Woyach, MD, Lindsey E. Roeker, MD, Philip A. Thompson, MBBS, Paolo Abada, MD, Caleb Ho, M.D., Narasimha Marella, Ph.D., Chunxiao Wang, Ph.D., Amy S. Ruppert, PhD, Binoj Chandrasekharan Nair, Ph.D., Hui Liu, Ph.D., Donald E. Tsai, MD, PhD and Paolo Ghia, MD, PhD
2122 Real World Experience with a Zuma -1 Cohort 4 Adopted Approach to CRS and Icans in CAR-T Recipients
Session: 705. Cellular Immunotherapies: Late Phase and Commercially Available Therapies: Poster I
Program: Oral and Poster Abstracts
Type: Poster
Time: 5:30 PM
Location: Halls G-H (San Diego Convention Center)Chiranjeevi Sainatham, MBBS, Olga Goloubeva, Philip Margiotta, MD, Hanan Alharthy, MBBS4, Imari Patel, Ali Bukhari, MD, MS, Jennie Law, MD, Seung Tae Lee, MD, Mehmet H. Kocoglu, MD, Jean A. Yared, MD, Nancy M. Hardy, MD, Maggie Nelson, PharmD, Joseph P McGuirk, DO, Aaron P. Rapoport, MD, Saurabh Dahiya and Forat Lutfi, MD
2133 Risk Factors and Outcomes for Hematotoxicity Following Tisagenlecleucel for Pediatric B-Acute Lymphoblastic Leukemia
Session: 705. Cellular Immunotherapies: Late Phase and Commercially Available Therapies: Poster I
Program: Oral and Poster Abstracts
Type: Poster
Time: 5:30 PM
Location: Halls G-H (San Diego Convention Center)Kevin O. McNerney, MD, MSc, Vanessa A. Fabrizio, MD, Aimee C. Talleur, MD, Stephanie Si Lim, MD, Alexandra Dreyzin, MD, Christina Baggott, PhD, Anant Vatsayan, MBBS, Jenna Rossoff, MD, Snehit Prabhu, PhD, Holly L. Pacenta, MD, Christine L Phillips, MD, Julie-An Talano, MD, Amy Moskop, MD, Michael R Verneris, MD, Douglas Myers, MD, Nicole Karras, MD, Challice L. Bonifant, MD, PhD, Muna Qayed, MD, Michelle L. Hermiston, MD, PhD, Prakash Satwani, MD, MBBS, Christa Krupski, DO, MPH, Amy Keating, MD, Susanne H.C. Baumeister, MD, Vasant Chinnabhandar, MD, MBBS, Emily Egeler, Kevin J Curran, MD, Crystal L. Mackall, MD, Theodore W. Laetsch, MD, Liora Michal Schultz, MD and Swati Naik, MBBS
2136 Use of Eltrombopag for Post-CAR T Cytopenias: A Multi-Institutional Experience
Session: 705. Cellular Immunotherapies: Late Phase and Commercially Available Therapies: Poster I
Program: Oral and Poster Abstracts
Type: Poster
Time: 5:30 PM
Location: Halls G-H (San Diego Convention Center)William Wesson, MPH, Nausheen Ahmed, MD, James A Davis, PharmD, Mary McGann, PharmD, Aliya Rashid, DO, MPH, Carine Tabak, Emerson Logan, Jose Marchena-Burgos, MBI, Maggie Nelson, PharmD, Leyla Shune, MD, Marc Hoffmann, MD, Al-Ola Abdallah, MD and Hamza Hashmi, MD
December 10, 2023
469 131I-Apamistamab-Led Allogeneic Hematopoietic Cell Transplant Significantly Improves Overall Survival in Patients with TP53 Mutated R/R AML
Session: 721. Allogeneic Transplantation: Conditioning Regimens, Engraftment and Acute Toxicities: Novel Conditioning Regimens for Myeloid Malignancies
Program: Oral and Poster Abstracts
Type: Oral
Time: 9:30 AM
Location: Pacific Ballroom Salons 18-19 (Marriott Marquis San Diego Marina)Hannah Choe, MD, Ben K. Tomlinson, MD, Boglarka Gyurkocza, MD, Rajneesh Nath, Stuart Seropian, MD, Mark R. Litzow, MD, Camille N. Abboud, MD, Patrick J. Stiff, MD, Sunil Abhyankar, MD, James M. Foran, MD, Sameem Abedin, MD, George Chen, MD, Zaid Al-Kadhimi, MD, Partow Kebriaei, MD, Mitchell Sabloff, MSc, MD, FRCPC, Johnnie J. Orozco, MD, PhD, Katarzyna Joanna Jamieson, MD, Margarida Magalhaes-Silverman, MD, Koen Van Besien, MD, PhD, Michael W. Schuster, MD, Arjun D. Law, MD, Sebastian A. Mayer, MD, Hillard M. Lazarus, MD, Jennifer Spross, Kate L Li, PhD, Elaina Haeuber, MS, Madhuri Vusirikala, Akash Nahar, MD, MPH, Brenda M. Sandmaier, MD, John Pagel, MD, PhD, Sergio A. Giralt, MD, FACP, Avinash Desai, M.D and Nebu Koshy, MD
469 131I-Apamistamab-Led Allogeneic Hematopoietic Cell Transplant Significantly Improves Overall Survival in Patients with TP53 Mutated R/R AML
Session: 732. Allogeneic Transplantation: Disease Response and Comparative Treatment Studies: Use of Molecular Techniques for Risk Stratification
Program: Oral and Poster Abstracts
Type: Oral
Time: 4:30 PM
Location: Pacific Ballroom Salons 18-19 (Marriott Marquis San Diego Marina)Hannah Choe, MD, Ben K. Tomlinson, MD, Boglarka Gyurkocza, MD, Rajneesh Nath, Stuart Seropian, MD, Mark R. Litzow, MD, Camille N. Abboud, MD, Patrick J. Stiff, MD, Sunil Abhyankar, MD, James M. Foran, MD, Sameem Abedin, MD, George Chen, MD, Zaid Al-Kadhimi, MD, Partow Kebriaei, MD, Mitchell Sabloff, MSc, MD, FRCPC, Johnnie J. Orozco, MD, PhD, Katarzyna Joanna Jamieson, MD, Margarida Magalhaes-Silverman, MD, Koen Van Besien, MD, PhD, Michael W. Schuster, MD, Arjun D. Law, MD, Sebastian A. Mayer, MD, Hillard M. Lazarus, MD, Jennifer Spross, Kate L Li, PhD, Elaina Haeuber, MS, Madhuri Vusirikala, Akash Nahar, MD, MPH, Brenda M. Sandmaier, MD, John Pagel, MD, PhD, Sergio A. Giralt, MD, FACP, Avinash Desai, M.D and Nebu Koshy, MD
655 Impact of Molecular Risk on Efficacy of Blood and Marrow Transplantation for Pediatric Acute Myeloid Leukemia: A Report from the Children’s Oncology Group, Clinically Relevant Abstract
Session: 623. Mantle Cell, Follicular, and Other Indolent B Cell Lymphomas: Clinical and Epidemiological: Poster I
Program: Oral and Poster Abstracts
Type: Poster
Time: 4:30 PM
Location: Marriott Grand Ballroom 5-6 (Marriott Marquis San Diego Marina)Benjamin J Huang, MD, Lauren K. Meyer, MD, PhD, Adam Lamble, MD, Jim Wang, MS, Rhonda E Ries, MA, Alan S Gamis, MD, MPH, Richard Aplenc, MD, PhD, Katherine Tarlock, MD, Todd Cooper, DO, E. Anders Kolb, MD, Todd A. Alonzo, PhD, Soheil Meshinchi, MD, PhD, Joseph Chewning, MD, William G. Woods, MD and John T. Horan, MD
601 Clinical Outcomes of Patients with Relapsed/Refractory Follicular Lymphoma Treated with Tisagenlecleucel: Phase 2 Elara 3-Year Follow-up, Clinically Relevant Abstract
Session: 623. Mantle Cell, Follicular, and Other Indolent B Cell Lymphomas: Clinical and Epidemiological: Immunotherapy
Program: Oral and Poster Abstracts
Type: Oral
Time: 4:30 PM
Location: Grand Hall C (Manchester Grand Hyatt San Diego)Stephen J Schuster, MD, Nathan Fowler, MD, Michael Dickinson, MBBS, D. Med Sci, FRACP, FRCPA, Joaquin Martinez-Lopez, MD, PhD, Arne Kolstad, MD, PhD, Jason Butler, MBBS, Monalisa Ghosh, MD, Leslie L. Popplewell, MD, FACP, MPH, Julio C Chavez, MD, Emmanuel Bachy, MD, PhD, Koji Kato, M.D., Ph.D., Hideo Harigae, Marie José Kersten, MD, PhD, Charalambos Andreadis, Peter A Riedell, Phoebe Joy Ho, MBBS, FRACP, FRCPA, Jose A. Perez-Simon, MD, PhD, Andy Chen, MD, PhD, Loretta J. Nastoupil, MD, Bastian von Tresckow, MD, Andrés José María Ferreri, MD, Takanori Teshima, Piers Patten, FRCP, FRCPath, PhD, Joseph P McGuirk, DO, Andreas L Petzer, MD, Fritz Offner, MD, Andreas Viardot, MD PhD, Pier Luigi Zinzani, MD, PhD, Ram Malladi, PhD, Aiesha Zia, Rakesh Awasthi, PhD, Ines Paule, Davide Germano, Roberto Javier Ramos, MD, Pei Hsu, Catherine Thieblemont, MD and Martin Dreyling, MD
617 Lisocabtagene Maraleucel in Relapsed/Refractory Large B-Cell Lymphoma: Real World Analysis from the Cell Therapy Consortium
Session: 627. Aggressive Lymphomas: Clinical and Epidemiological: Aiming for the Right Target: Using CAR-T and Bispecifics in Aggressive Lymphomas
Program: Oral and Poster Abstracts
Type: Oral
Time: 5:30 PM
Location: Ballroom 20AB (San Diego Convention Center)Peter A Riedell, MD, Connor Grady, MPH, Loretta J. Nastoupil, MD, Alejandro Luna, MD, PhD, Nausheen Ahmed, MD, Richard T Maziarz, MD, Marie Hu, MD, Jamie Brower, MS, Wei-Ting Hwang, PhD, Stephen J Schuster, MD, Andy Chen, MD, PhD, Olalekan O. Oluwole, MBBS, Veronika Bachanova, MD, PhD, Joseph P McGuirk, DO, Miguel-Angel Perales, MD, Michael R. Bishop, MD and David L. Porter, MD
617 Lisocabtagene Maraleucel in Relapsed/Refractory Large B-Cell Lymphoma: Real World Analysis from the Cell Therapy Consortium
Session: 652. Multiple Myeloma: Clinical and Epidemiological: Poster II
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Rawan Atallah, Yara Shatnawi, MD, Aytaj Mammadzadeh, Shahrukh K Hashmi, MD, MPH, Shabeeha K Rana, MBBS, MRCP, FRCPath, Muhammad Umair Mushtaq, MD, Benlazar Mohamed, MD, Nihar Desai, MBBS, Thiago Xavier Carneiro, MD, Rakesh Popat, Joseph P McGuirk, DO, Shebli Atrash, MD, Zahra Mahmoudjafari, PharmD, Al-Ola Abdallah, MD and Nausheen Ahmed, MD
3330 Toxicity and Efficacy Outcomes of Teclistamab in Patients with Relapsed-Refractory Multiple Myeloma (RRMM) Above the Age of 70 Years: A Multicenter Study
Session: 652. Multiple Myeloma: Clinical and Epidemiological: Poster II
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Danai Dima, MD, Aishwarya Sannareddy, MBBS, Nausheen Ahmed, MD, James A Davis, PharmD, Hira Shaikh, MBBS, Zahra Mahmoudjafari, PharmD, Marissa Duco, PharmD, Jack Khouri, MD, Gurbakhash Kaur, MD, MA, Jonathan Lochner, PharmD, Faiz Anwer, MD, Aimaz Afrough, MD, Jason Valent, MD, Hamza Hashmi, MD and Al-Ola Abdallah, MD
3361 Efficacy and Safety of Daratumumab, Pomalidomide and Dexamethasone Compared to Daratumumab, Carfilzomib and Dexamethasone in Daratumumab-Naïve Relapsed Multiple Myeloma: Multicenter Real-World Experience
Session: 652. Multiple Myeloma: Clinical and Epidemiological: Poster II
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Razan Mansour, James A Davis, PharmD, Megan Minchak, Rawan Atallah, Md Saiful Islam Saif, Emerson Logan, Carine Tabak, Aliya Rashid, DO, MPH, Danai Dima, MD, Nausheen Ahmed, MD, Al-Ola Abdallah, MD and Hamza Hashmi, MD
3499 Alternative Lymphodepletion Strategies Lead to Similar Response Rates and Toxicities in Standard-of-Care BCMA-Directed CAR-T Therapy in Relapsed Refractory Multiple Myeloma
Session: 705. Cellular Immunotherapies: Late Phase and Commercially Available Therapies: Poster II
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Shonali Midha, MD, BS, Ashwath Gurumurthi, MBBS, Patrick Costello, Robert A. Redd, MS, Ciara L. Freeman, PhD, MSc, FRCPC, MRCP, Omar Castaneda, MD, Rebecca Gonzalez, PharmD, Filip Ionescu, MD, Mahmoud Gaballa, MD, Nilesh Kalariya, PhD, RN, Jack Khouri, MD, Danai Dima, MD, Mehmet H. Kocoglu, MD, Douglas Sborov, MD, MS, Charlotte B Wagner, PharmD, Shebli Atrash, MD, Peter M. Voorhees, MD, Hamza Hashmi, MD, James A Davis, PharmD, Peter A. Forsberg, MD, Joseph P McGuirk, DO, Leyla Shune, MD, Megan Herr, PhD, Ran Reshef, MD, MSc, Yi Lin, MD, PhD, Myo Htut, MD, Thomas Martin, MD, Surbhi Sidana, MD, Doris K. Hansen, MD, Omar Nadeem, MD and Krina K. Patel, MD, MSc
3503 Impact of Frailty on Outcomes after CAR T-Cell Therapy for Patients with Relapsed/Refractory Multiple Myeloma
Session: 705. Cellular Immunotherapies: Late Phase and Commercially Available Therapies: Poster II
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)James A Davis, PharmD, Danai Dima, MD, Nausheen Ahmed, MD, Shaun DeJarnette, Joseph P McGuirk, DO, Jack Khouri, MD, Jason Valent, MD, Faiz Anwer, MD, Al-Ola Abdallah, MD and Hamza Hashmi, MD
3523 Comparison of Biosimilar Filgrastim (Nivestym) Versus Originator Filgrastim (Neupogen) for Peripheral Blood Stem Cell Mobilization for Allogeneic Hematopoietic Stem Cell Transplantation, Clinically Relevant Abstract
Session: 711. Cell Collection and Processing: Poster II Clinically Relevant Abstract
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Moazzam Shahzad, MD, Joe S. Al-Ramahi, Muhammad Kashif Amin, MD, Muhammad Fareed Khalid, MD, Shaun DeJarnette, Zahra Mahmoudjafari, PharmD, Maggie Nelson, PharmD, Riley Hastings, Haitham Abdelhakim, MD, Forat Lutfi, MD, Nausheen Ahmed, MD, Rajat Bansal, MD, Leyla Shune, MD, Al-Ola Abdallah, MD, Anurag K. Singh, MD, Sunil Abhyankar, MD, Joseph P McGuirk, DO and Muhammad Umair Mushtaq, MD
2700 Spatial Transcriptomics Reveals Distinct Hematopoietic Stem Cell Niches in Mouse Fetal Liver
Session: 506. Bone Marrow Microenvironment: Poster II
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Ruochen Dong, PhD, BM, Hua Li, Xi He, MD, Anoja Perera, Seth Malloy, Jonathon Russell, Wenting Li, Kaitlyn Petentler, Xinjian Mao, PhD, Zhe Yang, Michael Epp, Kate Hall, Allison Scott, Sarah Smith, Mark Hembree, Yongfu Wang, Sean McKinney, Jeff Haug, Jay Unruh, Brian Slaughter and Linheng Li, PhD
3187 Durable Clinical Benefits of Idasanutlin Therapy in Hydroxyurea-Refractory Polycythemia Vera
Session: 634. Myeloproliferative Syndromes: Clinical and Epidemiological: Poster II
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Julian Waksal, MD, Ronald Hoffman, MD, Abdulraheem Yacoub, MD, Francesco Passamonti, MD, Aaron T. Gerds, MD, MS, Vikas Gupta, MD, Grace Van Hyfte, Jayanshu Jain, MD, Margherita Maffioli, Natalia Rosas and John Mascarenhas, MD
2926 Relapse-Enriched Gene Expression Signature of Prognostic Relevance in Pediatric Acute Myeloid Leukemia
Session: 617. Acute Myeloid Leukemias: Biomarkers, Molecular Markers and Minimal Residual Disease in Diagnosis and Prognosis: Poster II
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Satyavardhan Rao Nittu, PharmD, Francisco Marchi, Nam Nguyen, MS, PharmD, Vivek M. Shastri, PhD, Xueyuan Cao, PhD, Raul C. Ribeiro, MD, Jeffrey E. Rubnitz, MD, PhD, Alan S Gamis, MD, MPH, E. Anders Kolb, MD, Richard Aplenc, MD, PhD, Jeffery Klco, MD, PhD, Stanley Pounds, PhD, Todd A. Alonzo, PhD, Soheil Meshinchi, MD, PhD and Jatinder K. Lamba, PhD
2956 Integrated Methylation and Transcriptional Landscape and Evolution of Pediatric AML
Session: 617. Acute Myeloid Leukemias: Biomarkers, Molecular Markers and Minimal Residual Disease in Diagnosis and Prognosis: Poster II
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Benjamin J Huang, MD, Hamid Bolouri, PhD, Colin Y. Smith, Jim Wang, MS, Rhonda E Ries, MA, Elizabeth Conran, Alan S Gamis, MD, MPH, Richard Aplenc, MD, PhD, Todd A. Alonzo, PhD, Xiaotu Ma, PhD, Timothy Junius Triche, PhD, Jason E. Farrar, MD and Soheil Meshinchi, MD, PhD
2983 Trajectory Inference Highlights Dynamic Expression of T-Cell Development Genes in Pediatric T-Cell Acute Lymphoblastic Leukemia
Session: 618. Acute Lymphoblastic Leukemias: Biomarkers, Molecular Markers and Minimal Residual Disease in Diagnosis and Prognosis: Poster II
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Irina Pushel, PhD, Byunggil Yoo, MS, Daniel Louiselle, MS, Margaret Gibson, MB(ASCP), Erin M. Guest, MD, Midhat S Farooqi, MD, PhD and Keith J. August, MD, MS
3391 Trial in Progress: A Phase 1 Study of KTX-1001, an Oral, First-in-Class, Selective MMSET Inhibitor in Patients with Relapsed and Refractory Multiple Myeloma
Session: 653. Multiple Myeloma: Prospective Therapeutic Trials: Poster II
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Jesus G. Berdeja, MD, David Dingli, MD, Sagar Lonial, MD, Andrew J. Yee, MD, Alfred Chung, MD, Cristina Gasparetto, MD, P. Leif Bergsagel, MD, Vivek Roy, MD, Al-Ola Abdallah, MD, Sharmilan Thanendrarajan, MD, Aimaz Afrough, MD, Laura Rosiñol, MD, PhD, Suzanne Trudel, MD, FRCPC, Paula Rodriguez Otero, MD, PhD, Cyrille Touzeau, MD, PhD, Pierre Bories, MD, PhD, Soo Bang, MHSA, Terry Connolly, PhD, Michelle Kim, Chad A. Lewis, PhD, Bao-Van Tran Linberg, M. Travis Quigley, Ola Landgren, MD, Saad Z Usmani, MD, Maria-Victoria Mateos and David S. Siegel, MD, PhD
3088 Chimeric Antigen Receptor T-Cell (CAR-T) Therapy in Secondary Central Nervous System Large B-Cell Lymphoma (SCNSL): A Multicenter Retrospective Analysis
Session: 626. Aggressive Lymphomas: Prospective Therapeutic Trials: Poster II
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Gulrayz Ahmed, MD, FACP, Aseel Alsouqi, MD, Aniko Szabo, PhD, Alexandra E. Rojek, MD, Peter A. Riedell, MD, Farrukh T. Awan, MD, Laura Samples, MD, Mazyar Shadman, MD, MPH, Marie Hu, MD, Veronika Bachanova, MD, PhD, William Wesson, MPH, Nausheen Ahmed, MD, Madiha Iqbal, MD11, Mohamed A. Kharfan-Dabaja, MD, MBA12, Michael Scordo13, Patrick Connor Johnson, MD, Yi-Bin Chen, MD, MS, Sawa Ito, MD, Mehdi Hamadani, MD and Matthew J. Frigault, MD, MS
2877 Assessment of Outcomes of Consolidation Therapy By Number of Cycles of Blinatumomab Received in Newly Diagnosed Measurable Residual Disease Negative Patients with B-Lineage Acute Lymphoblastic Leukemia: In the ECOG-ACRIN E1910 Randomized Phase III National Clinical Trials Network Trial
Session: 614. Acute Lymphoblastic Leukemias: Therapies, Excluding Transplantation and Cellular Immunotherapies: Poster II
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Selina M Luger, MD, FRCPC, Zhuoxin Sun, PhD, Ryan J Mattison, MD, Elisabeth Paietta, PhD, Kathryn G. Roberts, PhD, Yanming Zhang, M.D., Janis Racevckis, Hillard M. Lazarus, MD, Jacob M. Rowe, MB, BS, Daniel A. Arber, MD, Matthew J. Wieduwilt, MD, Michaela Liedtke, MD, Julie Bergeron, MD, Brent L. Wood, MD, PhD, Yaqi Zhao, MSc, Gang Wu, PhD, Ti-Cheng Chang, Wenchao Zhang, Keith W Pratz, MD, Shira N. Dinner, MD, Noelle V. Frey, MD, MS, Steven D. Gore, MD, Bhavana Bhatnagar, DO, Ehab L. Atallah, MD, Geoffrey L Uy, MD, Deepa Jeyakumar, MD, Tara L Lin, MD, Cheryl L. Willman, MD, Daniel J. DeAngelo, Elad Sharon, MD, MPH, Richard F. Little, MD, MPH, Harry P. Erba, MD, PhD, Richard M Stone, MD, Charles G. Mullighan, MBBS, MD, Mark R. Litzow, MD and Martin S. Tallman, MD
3529 High-Dose Targeted Radiation with 131I-Apamistamab Prior to HCT Demonstrated a Dose-Response for Durable Complete Remission in Patients with R/R AML
Session: 721. Allogeneic Transplantation: Conditioning Regimens, Engraftment and Acute Toxicities: Poster II
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Mark R. Litzow, MD, George Chen, MD, Boglarka Gyurkocza, MD, Rajneesh Nath, Stuart Seropian, MD, Hannah Choe, MD, Camille N. Abboud, MD, Nebu Koshy, MD, Ben K. Tomlinson, MD, Sunil Abhyankar, MD, James M. Foran, MD, Sameem Abedin, MD, Zaid Al-Kadhimi, MD, Partow Kebriaei, MD, Mitchell Sabloff, MSc, MD, FRCPC, Johnnie J. Orozco, MD, PhD, Katarzyna Joanna Jamieson, MD, Margarida Magalhaes-Silverman, MD, Koen Van Besien, MD, PhD, Michael W. Schuster, MD, Arjun D. Law, MD, Sebastian A. Mayer, MD, Hillard M. Lazarus, MD, Eugene Leung, MD, FRCPC, Ming-Kai Chen, MD, PhD, Mona Natwa, MD, Jennifer Spross, Kate L Li, PhD, Norman Nagl, PhD, Elaina Haeuber, MS, Madhuri Vusirikala, Akash Nahar, MD, MPH, Brenda M. Sandmaier, MD, John Pagel, MD, PhD, Sergio A. Giralt, MD, FACP, Avinash Desai, M.D, Richard L. Wahl, MD, Neeta Pandit-Taskar, MD, Patrik Brodin and Patrick J. Stiff, MD
December 11, 2023
835 A DNA Methylation Signature Predicts Clinical Outcome in Pediatric AML Patients
Session: 617. Acute Myeloid Leukemias: Biomarkers, Molecular Markers and Minimal Residual Disease in Diagnosis and Prognosis: Deciphering Risk by Genetic and Epigenetic Features
Program: Oral and Poster Abstracts
Type: Oral
Time: 2:45 PM
Location: Pacific Ballroom Salons 15-17 (Marriott Marquis San Diego Marina)Francisco Marchi, Marieke Landwehr, Fernando Sckaff, Xueyuan Cao, PhD, Raul C. Ribeiro, MD, Jeffrey E. Rubnitz, MD, PhD, Alan S Gamis, MD, MPH, E. Anders Kolb, MD, Richard Aplenc, MD, PhD, Stanley Pounds, PhD, Todd A. Alonzo, PhD, Soheil Meshinchi, MD, PhD and Jatinder K. Lamba, PhD
1027 Real World Outcomes with Idecabtagene Vicleucel (Ide-Cel) CAR-T Cell Therapy for Relapsed/Refractory Multiple Myeloma
Session: 705. Cellular Immunotherapies: Late Phase and Commercially Available Therapies: Cellular Therapy for Multiple Myeloma, B-cell Acute Lymphoblastic Leukemia and B Cell Lymphomas: Clinical Trial and Real-World Evidence
Program: Oral and Poster Abstracts
Type: Oral
Time: 4:30 PM
Location: Room 6CF (San Diego Convention Center)Surbhi Sidana, MD, Nausheen Ahmed, MD, Othman S Akhtar, MD, Michael Heim, MS, Ruta Brazauskas, PhD, Doris K. Hansen, MD, Christopher Ferreri, MD, Ciara L. Freeman, PhD, MSc, FRCPC, MRCP, Aimaz Afrough, MD, Larry D. Anderson Jr., MD, PhD, Binod Dhakal, MD, MS, Devender Dhanda, PhD, Lohith Gowda, MD, Hamza Hashmi, MD, Melanie Harrison, Amani Kitali, MBA, MPH, PMP, Sayeef Mirza, MD, MPH, Jinalben Patel, MPH, Pallavi Patwardhan, Saad Z Usmani, MD, Krina K. Patel, MD, MSc, Siddhartha Ganguly, MD and Marcelo Pasquini, MD, MS
973 Post-Hoc Analysis of Measurable Residual Disease from BMT-CTN 1506/Morpho: FLT3-ITD Variant Allele Frequency and Survival Are Highly Correlated Clinically Relevant Abstract
Session: 617. Acute Myeloid Leukemias: Biomarkers, Molecular Markers and Minimal Residual Disease in Diagnosis and Prognosis: Response Predictors to Targeted Therapies and Transplant
Program: Oral and Poster Abstracts
Type: Oral
Time: 4:30 PM
Location: Pacific Ballroom Salons 15-17 (Marriott Marquis San Diego Marina)Mark J. Levis, MD, PhD, Mehdi Hamadani, MD, Brent R. Logan, PhD, Richard J. Jones, MD, Anurag K. Singh, MD, Mark R. Litzow, MD, John R. Wingard, MD, Esperanza B. Papadopoulos, MD, Alexander Perl, Robert J. Soiffer, MD, Celalettin Ustun, MD, Masumi Ueda Oshima, MD, Geoffrey L Uy, MD, Edmund K. Waller, MD, Sumithira Vasu, MD, MBBS, Melhem M. Solh, MD, Asmita Mishra, MD, MBA, Lori S. Muffly, MD, Hee-Je Kim, Matthias Stelljes, MD, Yuho Najima, MD, PhD, Masahiro Onozawa, M.D., Ph.D., Kirsty Thomson, MB ChB, Arnon Nagler, MD, M.Sc, Andrew H. Wei, MBBS, PhD, Guido Marcucci, MD, Nahla Hasabou, MD, Mathew Rosales, PhD, Jason Hill, PhD, Stanley C. Gill, PhD, Rishita Nuthethi, PhD, Denise King, MS, CCRA, Heather Wittsack, MPH, Adam Mendizabel, PhD, Steven M. Devine, MD, Mary M. Horowitz, MD and Yi-Bin Chen, MD, MS
981 Pirtobrutinib in Relapsed/Refractory (R/R) Mantle Cell Lymphoma (MCL) Patients with Prior cBTKi: Safety and Efficacy Including High-Risk Subgroup Analyses from the Phase 1/2 BRUIN Study
Session: 653. Multiple Myeloma: Prospective Therapeutic Trials: Relapsed and Refractory Myeloma Clinically Relevant Abstract
Program: Oral and Poster Abstracts
Type: Oral
Time: 5 PM
Location: Room 6CF (San Diego Convention Center)Jonathon B. Cohen, MD, MS, Nirav N. Shah, MD, Wojciech Jurczak, MD, PhD, Pier Luigi Zinzani, MD, PhD, Chan Y. Cheah, MBBS, FRACP, FRCPA, DMSc, Toby A. Eyre, Chaitra S Ujjani, MD, Youngil Koh, MD, Won Seog Kim, MD, MPH, PhD, Sunita D. Nasta, MD, FACP, Ian W. Flinn, MD, PhD, Benoit Tessoulin, Shuo Ma, MD, PhD, Alvaro J. Alencar, MD, David Lewis, MBChB, PHD, Jennifer A. Woyach, MD, Kami J. Maddocks, MD, Krish Patel, MD, Yucai Wang, MD, PhD, Joanna M. Rhodes, MD, MSCE, Constantine S. Tam, MD, MBBS, John F. Seymour, MBBS, PhD, FRACP, Hirokazu Nagai, MD, PhD, Julie M. Vose, MD, MBA, Bita Fakhri, MD, MPH, Marc Hoffmann, MD, Francisco J. Hernandez-Ilizaliturri, MD, Andrew D. Zelenetz, MD, PhD, Anita Kumar, MD, Talha Munir, MBBS, MRCP, FRCPath, PhD, Donald E. Tsai, MD, PhD, Minna Balbas, PhD, Bin Liu, MSc, MPH, Amy S. Ruppert, PhD, Bastien Nguyen, PhD, Lindsey E. Roeker, MD and Michael L. Wang, MD
1012 Results from the Completed Dose Escalation Portion of the Phase 1 Study of HPN217, a Half-Life Extended Tri-Specific T Cell Activating Construct (TriTAC®) Targeting B Cell Maturation Antigen (BCMA) for Relapsed/Refractory Multiple Myeloma (MM)
Session: 653. Multiple Myeloma: Prospective Therapeutic Trials: Relapsed and Refractory Myeloma Clinically Relevant Abstract
Program: Oral and Poster Abstracts
Type: Oral
Time: 5:15 PM
Location: Room 6CF (San Diego Convention Center)Sumit Madan, MD, Caitlin L. Costello, MD, Brea Lipe, MD, Andrew J. Cowan, MD, Eva Medvedova, MD, Jens Hillengass, MD, PhD, P. Leif Bergsagel, MD, Xavier Leleu, MD, Cyrille Touzeau, MD, PhD, Daniel Morillo, MD, Albert Oriol, Raya Mawad, MD, Henning Schade, MD, Salomon Manier, MD, PhD, Yifah Yaron, MD, PhD, Banmeet Anand, PhD and Al-Ola Abdallah, MD
1032 Five Year Outcomes of Patients with Large B-Cell Lymphoma Treated with Standard-of-Care Axicabtagene Ciloleucel: Results from the US Lymphoma CAR-T Cell Consortium
Session: 705. Cellular Immunotherapies: Late Phase and Commercially Available Therapies: Cellular Therapy for Multiple Myeloma, B-cell Acute Lymphoblastic Leukemia and B Cell Lymphomas: Clinical Trial and Real-World Evidence
Program: Oral and Poster Abstracts
Type: Oral
Time: 5:45 PM
Location: Room 6CF (San Diego Convention Center)Jay Y. Spiegel, MD, FRCPC, Michael D. Jain, MD, PhD, Loretta J. Nastoupil, MD, John Tamaresis, PhD, Armin Ghobadi, MD, Yi Lin, MD, PhD, Lazaros J. Lekakis, Patrick M. Reagan, MD, Olalekan O. Oluwole, MBBS, Joseph P McGuirk, DO, Abhinav Deol, MD, Kathleen Dorritie, MD, Alison R Sehgal, MD, Andre Goy, MD, Brian T. Hill, MD, Charalambos Andreadis, MD, Javier L. Munoz, Matthew L. Ulrickson, MD, Jason Westin, MD, Julio C. Chavez, MD, Dilan A Patel, Miriam T. Jacobs, MD, Radhika Bansal, MBBS, N. Nora Bennani, MD, Vivek Patel, MD, Aaron P. Rapoport, MD, Julie M. Vose, MD, MBA, David B. Miklos, MD, PhD, Sattva S. Neelapu, MD, Frederick L. Locke, MD, Matthew A. Lunning, DO, FACP and Saurabh Dahiya
4876 Second-Line Chimeric Antigen Receptor T Cell Therapy (CAR-T) As Standard of Care for Relapsed-Refractory Large B-Cell Lymphoma (LBCL)
Session: 705. Cellular Immunotherapies: Late Phase and Commercially Available Therapies: Poster III
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Saurabh Dahiya, Jay Y. Spiegel, MD, FRCPC, Dasom Lee, MD, Turab Mohammed, MD, Forat Lutfi, MD, Anmol Goyal, MD, Caroline Hana, Julio C Chavez, MD, Filip Ionescu, MD, Matthew J. Frank, MD, PhD, Sushma Bharadwaj, MD, MS, Jose Sandoval-Sus, MD, Amer M. Beitinjaneh, MD, MS, Lazaros J. Lekakis, Joseph P McGuirk, DO, Frederick L. Locke, MD, David B. Miklos, MD, PhD and Michael D. Jain, MD, PhD
4880 Fludarabine Lymphodepletion Exposure Is Associated with Idecabtagene Vicleucel Toxicity in Relapsed and Refractory Multiple Myeloma Patients: Real-World Experience from the US Myeloma Immunotherapy Consortium
Session: 705. Cellular Immunotherapies: Late Phase and Commercially Available Therapies: Poster III
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Charlotte B Wagner, PharmD, Karen Sweiss, PharmD2, Eric Anto, M.S., Rebecca Gonzalez, PharmD, Omar Alexis Castaneda Puglianini, MD, Ciara L. Freeman, PhD, MSc, FRCPC, MRCP, Filip Ionescu, MD, Krina K. Patel, MD, MSc, Christopher Ferreri, MD, Mahmoud Gaballa, MD, Leyla Shune, MD, Joseph P McGuirk, DO, Surbhi Sidana, MD, Vanna Hovanky, MS, Jack Khouri, MD, Danai Dima, MD, Hamza Hashmi, MD, James A Davis, PharmD, Aimaz Afrough, MD, Gurbakhash Kaur, MD, MA, Larry D. Anderson Jr., MD, PhD, Peter A. Forsberg, MD, Megan Herr, PhD, Doris K. Hansen, MD, Douglas Sborov, MD, MS and Mehmet H. Kocoglu, MD
4882 Outcomes of BCMA-Directed Chimeric Antigen Receptor T-Cell (CART) Therapy in Patients with Relapse-Refractory Multiple Myeloma with Extramedullary Disease
Session: 705. Cellular Immunotherapies: Late Phase and Commercially Available Therapies: Poster III
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Danai Dima, MD, James A Davis, PharmD, Aliya Rashid, DO, MPH, Mikhaila Rice, PharmD, Shaun DeJarnette, Leyla Shune, MD, Jack Khouri, MD, Shahzad Raza, MD, Joseph P McGuirk, DO, Faiz Anwer, MD, Nausheen Ahmed, MD, Al-Ola Abdallah, MD and Hamza Hashmi, MD
4885 Efficacy and Safety of Idecabtagene Vicleucel (ide-cel) in Patients with Relapsed-Refractory Multiple Myeloma (RRMM) Not Meeting the Karmma Trial Eligibility Criteria: A Real-World Multicenter Study
Session: 705. Cellular Immunotherapies: Late Phase and Commercially Available Therapies: Poster III
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Danai Dima, MD, Aliya Rashid, DO, MPH, James A Davis, PharmD, Hussein Awada, Al-Ola Abdallah, MD, Hong Li, MS, Shaun DeJarnette, Leyla Shune, MD, Jack Khouri, MD, Hamza Hashmi, MD, Joseph P McGuirk, DO, Faiz Anwer, MD and Nausheen Ahmed, MD
4887 Defining the Optimal Post-CART Monitoring Period in Recipients of Axicabtagene Ciloleucel and Tisagenlecleucelâ
Session: 705. Cellular Immunotherapies: Late Phase and Commercially Available Therapies: Poster III
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)William Wesson, MPH, Forat Lutfi, MD, David L. Porter, MD, Veronika Bachanova, MD, PhD, Loretta J. Nastoupil, MD, Peter A. Riedell, MD, Miguel-Angel Perales, MD, Richard T Maziarz, MD, Jamie Brower, MS, Gunjan L. Shah, Andy Chen, MD, PhD, Olalekan O. Oluwole, MBBS, Stephen J Schuster, MD, Michael R. Bishop, MD, Joseph P McGuirk, DO and Nausheen Ahmed, MD
4296 Genomic Characterization of Newly Diagnosed Acute Myeloid Leukemia in Patients Age 60 Years and Older; A Report from the Beat AML Master Trial
Session: 617. Acute Myeloid Leukemias: Biomarkers, Molecular Markers and Minimal Residual Disease in Diagnosis and Prognosis: Poster III
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Fieke W Hoff, MD, PhD, Ying Huang, MS, MA, Rina Li Welkie, MPH, Ronan T. Swords, MD, PhD, FRCP, FRCPath, Elie Traer, Eytan M. Stein, Tara L Lin, MD, Prapti A. Patel, MD, Robert H. Collins, MD, Maria R. Baer, MD, Vu H. Duong, MD, MS, William Blum, MD, Martha Arellano, Wendy Stock, MD, Olatoyosi Odenike, Robert L. Redner, MD, Tibor J. Kovacsovics, MD, Michael W. Deininger, MD, PhD, Joshua F. Zeidner, MD, Rebecca Olin, MD MSCE, Catherine C. Smith, MD, James M. Foran, MD, Gary J. Schiller, MD, Emily K Curran, MD, Kristin L Koenig, MD, Nyla A. Heerema, PhD, Timothy Chen, PhD, Molly Martycz, Mona Stefanos, MD, Sonja Gullen Marcus, MPH, Leonard Rosenberg, Brian J. Druker, MD, Ross L Levine, MD, Amy Burd, PhD, Ashley Owen Yocum, PhD, Uma M. Borate, MBBS, MS, Alice Mims, MD, John C. Byrd, MD and Yazan F. Madanat, MD
4306 DNMT3A Mutants Are Enriched in NPMc+ AML and Associated with Adverse Outcome in Childhood AML
Session: 617. Acute Myeloid Leukemias: Biomarkers, Molecular Markers and Minimal Residual Disease in Diagnosis and Prognosis: Poster III
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Rhonda E Ries, MA, Xiaotu Ma, PhD, Claudia Tregnago, PhD, Todd A. Alonzo, PhD, Jim Wang, MS, Tiffany Hylkema, BS, Benjamin J Huang, MD, Alireza Torabi, MD, PhD, Jack H Peplinski, BS, Logan K Wallace, Richard Aplenc, MD, PhD, Alan S Gamis, MD, MPH, Katherine Tarlock, MD, Franco Locatelli, MD, PhD, Martina Pigazzi, PhD and Soheil Meshinchi, MD, PhD
4314 ACS10- Cytarabine Pharmacogenomics Score Impacts Survival in Pediatric AML Patients Treated on AAML1031 Trial and Associates with Outcome Differences in Black AML Patients
Session: 617. Acute Myeloid Leukemias: Biomarkers, Molecular Markers and Minimal Residual Disease in Diagnosis and Prognosis: Poster III
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Richard J Marrero, PharmD, Vivek M. Shastri, PhD, Richard Aplenc, MD, PhD, Todd Cooper, DO, Todd A. Alonzo, PhD, Alan S Gamis, MD, MPH, Jim Wang, MS, Soheil Meshinchi, MD, PhD, E. Anders Kolb, MD and Jatinder K. Lamba, PhD
4332 Influence of Pre-Treatment Features and Therapy Choice By Physicians on Overall Survival in Older Adults with Acute Myeloid Leukemia: A Report from the Beat AML Master Trial, Clinically Relevant Abstract
Session: 617. Acute Myeloid Leukemias: Biomarkers, Molecular Markers and Minimal Residual Disease in Diagnosis and Prognosis: Poster III
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Uma M. Borate, MBBS, MS, Ying Huang, MS, MA, Rina Li Welkie, MPH, Ronan T. Swords, MD, PhD, FRCP, FRCPath, Elie Traer5, Eytan M. Stein, Tara L Lin, MD, Yazan F. Madanat, MD, Prapti A. Patel, MD, Robert H. Collins, MD, Maria R. Baer, MD, Vu H. Duong, MD, MS, William Blum, MD, Martha Arellano, Wendy Stock, MD, Olatoyosi Odenike, Robert L. Redner, MD, Tibor J. Kovacsovics, MD, Michael W. Deininger, MD, PhD, Joshua F. Zeidner, MD, Rebecca Olin, MD MSCE, Catherine C. Smith, MD, James M. Foran, MD, Gary J. Schiller, MD, Emily K Curran, MD, Kristin L Koenig, MD, Nyla A. Heerema, PhD, Timothy Chen, PhD, Molly Martycz, Mona Stefanos, MD, Sonja Gullen Marcus, MPH, Leonard Rosenberg, Brian J. Druker, MD, Ross L Levine, MD, Amy Burd, PhD, Ashley Owen Yocum, PhD, Alice Mims, MD and John C. Byrd, MD
4295 Anti-Leukemic Activity of Luveltamab Tazevibulin (LT, STRO-002), a Novel Folate Receptor-α (FR-α)-Targeting Antibody Drug Conjugate (ADC) in Relapsed/Refractory CBF2AT3::GLIS2 AML
Session: 616. Acute Myeloid Leukemias: Investigational Therapies, Excluding Transplantation and Cellular Immunotherapies: Poster III
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Robin Williams, MD, MS, Lane Miller, MD, MSc, Stephanie Massaro, MD, MPH, Elizabeth Krieger, MD, Melinda Pauly, MD, Catherine Nelson, DO, MS, Rebecca Johnson, MD, Jennifer J.G. Welch, MD, Deepa Bhojwani, MD, Babak Moghimi, MD, Philip Neff, MD, Terzah M. Horton, MD, PhD, Hamayun Imran, MBBS, MD, Raul C. Ribeiro, MD, Terri L. Guinipero, MD, Matthew A. Kutny, MD, Felipe Bautista, MD, Amy Johnson, MD, Karen Lewing, MD, Alan S Gamis, MD, MPH, Julienne Brackett, MD, MS, David McCall, MD, Teena Bhatla, MD, Maria Luisa Sulis, MD, Amy Tellinghuisen, MD, Jill C. Beck, MD and Soheil Meshinchi, MD, PhD
4005 Thermodynamic Effects of Antibodies on VWF73 Cleavage By ADAMTS13
Session: 331. Thrombotic Microangiopathies/Thrombocytopenias and COVID-19-related Thrombotic/Vascular Disorders: Clinical and Epidemiological: Poster III
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Chan Meng, MD, Konstantine Halkidis, MD, PhD, Szumam Liu, PhD and X. Lianng Zheng, MD, PhD
4051 Characterization of Niche Cells and Signals Regulating Stepwise Embryonic Hematopoiesis Using Slide-Seq and Merfish Spatial Transcriptomics
Session: 501. Hematopoietic Stem and Progenitor Cells and Hematopoiesis: Basic and Translational: Poster III
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Xinjian Mao, PhD, Ning Zhang, Xi He, MD, Kate Hall, Kaitlyn Petentler, Allison Scott, Seth Malloy, Jeff Haug, Hua Li, Anoja Perera, Jay Unruh, Brian Slaughter, Nancy Speck and Linheng Li, PhD
4459 Golcadomide (GOLCA; CC-99282), a Novel CELMoD Agent, Plus R-CHOP in Patients (pts) with Previously Untreated Aggressive B-Cell Lymphoma (a-BCL): Safety and Efficacy Results from Phase 1b Dose Expansion
Session: 626. Aggressive Lymphomas: Prospective Therapeutic Trials: Poster III
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Marc Hoffmann, MD, Javier L. Munoz, Jason Westin, MD, Theodoros Vassilakopoulos, PhD, Alejandro Martin Garcia-Sancho, MD, Antonio Rueda Dominguez, MD, Wojciech Jurczak, MD, PhD, Su-Peng Yeh, MD, Maria Bouzani, Argyrios Gkasiamis, MD, Mark Kaplan, Arpankumar Patel, Floriane Boucaud, Ju Li and Grzegorz S. Nowakowski, MD
4475 Copanlisib in Combination with Nivolumab in Subjects with Relapsed/Refractory Diffuse Large B-Cell Lymphoma and Primary Mediastinal Large B-Cell Lymphoma: A Phase II Study
Session: 626. Aggressive Lymphomas: Prospective Therapeutic Trials: Poster III
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)N. Nora Bennani, MD, Pamela Atherton, Kimberly O Steinert, Lisa M. Rimsza, MD, Aung M. Tun, MD, Marc Hoffmann, MD, Mayur S. Narkhede, MBBS, Rakhee Vaidya, MD, Rabih Said, Geoffrey I Shapiro, MD, Brian A Costello, MD, Stephen M Ansell, MD, PhD and Grzegorz S. Nowakowski, MD
4227 Characteristics and Outcomes of Patients with DDX41-Mutated Acute Myeloid Leukemia: A Single-Center Experience
Session: 613. Acute Myeloid Leukemias: Clinical and Epidemiological: Poster III
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Jayanshu Jain, MD, Kenneth P Byrd, DO, Heather J Male, MD, Haitham Abdelhakim, MD, Jesus D Gonzalez-Lugo, MD and Tara L Lin, MD
4727 Global Access to Multiple Myeloma Medications (GLAMM-2 Study): Access and Barriers to Chemoimmunotherapies and Transplant
Session: 652. Multiple Myeloma: Clinical and Epidemiological: Poster III Clinically Relevant Abstract
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Aytaj Mammadzadeh, Yara Shatnawi, MD, Rawan Atallah, Benlazar Mohamed, MD, Nihar Desai, MBBS, Shahrukh K Hashmi, MD, MPH, Thiago Xavier Carneiro, MD, Hira Shaikh, MBBS, Christopher Strouse, MD, Rakesh Popat, Zahra Mahmoudjafari, PharmD, Muhammad Umair Mushtaq, MD, Al-Ola Abdallah, MD and Nausheen Ahmed, MD
4853 Inb-100: A Pilot Study of Donor Derived, Ex-Vivo Expanded/Activated Gamma-Delta T Cell (EAGD) Infusion Following Haploidentical Hematopoietic Stem Cell Transplantation and Post-Transplant Cyclophosphamide (PTCy)
Session: 704. Cellular Immunotherapies: Early Phase and Investigational Therapies: Poster III
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Joseph P McGuirk, DO, Sunil Abhyankar, MD, Trishna Goswami, MD, MBA, Halie Juarez, RN, Mariska ter Haak, Tyce Bruns, Samantha Youngblood and Lawrence S. Lamb, PhD
4921 A Phase 2, Single-Arm, Multicohort, Open Label, Multicenter Trial of Off-the-Shelf Natural Killer Cells (SAR445419) in Patients with High-Risk Myeloid Malignancies Undergoing Allogeneic HSCT
Session: 704. Cellular Immunotherapies: Early Phase and Investigational Therapies: Poster III
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Monzr M. Al Malki, MD, Melhem M. Solh, MD, Anurag K. Singh, MD, Rushang D. Patel, MD, PhD, Denis-Claude Roy, MD, Agata Drewniak, PhD, Gu Mi, PhD, Lorraine Tracey, PhD, Giovanni Abbadessa, MD, PhD and Richard E. Champlin, MD
4554 Platelet Response in Pacritinib-Treated Patients with Cytopenic Myelofibrosis: A Retrospective Analysis of PERSIST-2 and PAC203 Studies
Session: 634. Myeloproliferative Syndromes: Clinical and Epidemiological: Poster III
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Pankit Vachhani, MD, Abdulraheem Yacoub, MD, Elie Traer, Lina Benajiba, Francesco Passamonti, Ashwin Kishtagari, MBBS, Mojtaba Akhtari, James McCloskey, MD, Sarah Buckley, MD, Purvi Suthar, Karisse Roman-Torres and John Mascarenhas, MD
4502 Efficacy of Siltuximab for Chimeric Antigen Receptor T-Cell Therapy Toxicities – a Multicenter Retrospective Analysis
Session: 627. Aggressive Lymphomas: Clinical and Epidemiological: Poster III
Program: Oral and Poster Abstracts
Type: Poster
Time: 6 PM
Location: Halls G-H (San Diego Convention Center)Amneet K Bajwa, MD, MBA, Qiuhong Zhao, MS, Marcus Johannes Geer, MD, Agrima Mian, MD, MBBS, Chenyu Lin, MD, David Frame, PharmD, James Westholder, PharmD, Justin Tossey, PharmD, Monalisa Ghosh, MD, Ahmed Galal, MD, Nausheen Ahmed, MD, Joseph E. Maakaron, MD, Nathan Denlinger, MS, DO, Marcos de Lima, MD, Narendranath Epperla, MD, MS, Paolo F. Caimi, MD and Timothy Voorhees, MD, MSCR
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December 5, 2023
Hormone replacement and alternatives for relief of vasomotor symptoms in women at increased risk for breast cancer
Session Title: Concurrent Special Session 2: Prevention, Early Detection, and Interception
Session Date/Time: Tuesday, December 5, 12 - 2 PM
Session Location: Stars at Night Ballroom 3-4
Carol J. Fabian (presenter and moderator)
December 6, 2023
PO1-06-03 Efficacy of First-line Treatments for Hormone Receptor-positive, Human Epidermal Growth Factor Receptor 2-positive Metastatic Breast Cancer: A Systematic Literature Review and Network Meta-analysis Feasibility Assessment.
Session Title: Poster Session 1
Session Date/Time: Wednesday, December 6, 12 - 2 PM
Session Location: Halls 2-3
Priyanka Sharma, Chau Dang, Christopher Drudge, Amrita Debnath, Manvir Rai, Eric Gauthier, Edward Broughton
PO2-08-10 Effect of 6 months of bazedoxifene + conjugated estrogens on body composition and insulin resistance.
Session Title: Poster Session 2
Session Date/Time: Wednesday, December 6, 5 - 7 PM
Session Location: Halls 2-3
Carol Fabian, Adrian Zelenchuk, Kandy Powers, Amy Kreutzjans, Krystal Pittman, Bill Hendry, Christy Altman, Erin Giles, Katherine L. Cook, Stephen Hursting, Bruce Kimler.
PO2-13-07 SMARCA2 compensation of SMARCA4 loss mediates adaptive resistance to neoadjuvant systemic therapy in triple-negative breast cancer: paired transcriptomic analysis of pre- and posttreatment samples from NeoSTOP and NeoPACT.
Session Title: Poster Session 2
Session Date/Time: Wednesday, December 6, 5 - 7 PM
Session Location: Halls 2-3
Shane Stecklein, Rachel Yoder, Joshua Staley, Zachary Schmitt, Anne O'Dea, Lauren Nye, Deepti Satelli, Gregory Crane, Rashna Madan, Maura O'Neil, Andrew Godwin, Harsh Pathak, Qamar Khan, Joyce O'Shaughnessy, Priyanka Sharma
PS07-08 Bazedoxifene plus conjugated estrogen reduces mammary proliferation markers and improves adipocyte size, gut microbiome, and metabolic health: Findings from a preclinical model of obesity and breast cancer risk.
Session Title: Concurrent Poster Spotlight Sessions Block 3, PS07 Prevention
Session Date/Time: Wednesday, December 6, 5:30 - 6:30 PM
Session Location: Stars at Night Ballroom 3-4
Katherine L. Cook, Ramsey Jenshcke, Karen Corleto, Carol Fabian, Stephen Hursting, Bruce Kimler, Danilo Landrock, Erin GilesDecember 7, 2023
PS07-08 Bazedoxifene plus conjugated estrogen reduces mammary proliferation markers and improves adipocyte size, gut microbiome, and metabolic health: Findings from a preclinical model of obesity and breast cancer risk.
Session Title: Concurrent Poster Spotlight Sessions Block 4, PS12 Putting Brakes on the Cell Cycle: Understanding Mechanisms Governing CDK 4/6 inhibitor Resistance and Role for Novel Therapeutic Strategies
Session Date/Time: Thursday, December 7, 7 - 8 AM
Session Location: Stars at Night Ballroom 3-4
Cook KL, Jenshcke R, Corletto K, Fabian CJ, Hursting SD, Kimler BF, Landrock D, Giles ED.
PS12-03 p53 loss enables HR+ breast cancer escape from CDK4/6 inhibitor-induced quiescence via CDK2
Session Title: Concurrent Poster Spotlight Sessions Block 4, PS12 Putting Brakes on the Cell Cycle: Understanding Mechanisms Governing CDK 4/6 inhibitor Resistance and Role for Novel Therapeutic Strategies
Session Date/Time: Thursday, December 7, 7 - 8 AM
Session Location: Stars at Night Ballroom 3-4
Rei Kudo, Anton Safonov, Edaise M. da Silva, Qing Li, Hong Shao, Marie Will, Harikrishna Nakshatri, Jorge Reis-Filho, Shom Goel, Andrew Koff, Britta Weigelt, Qamar Khan, Pedram Razavi, Sarat Chandarlapaty
PO3-05-14 Practice patterns for sequential use of antibody-drug conjugate after antibody-drug conjugate in metastatic breast cancer: results from a physician survey.
Session Title: Poster Session 3
Session Date/Time: Thursday, December 7, 12 - 2 PM
Session Location: Halls 2-3
Yara Abdou, Prarthna Bhardwaj, Rachel Abelman, Laura Spring, Aditya Bardia, Lisa Carey, Priyanka Sharma
PO3-16-05 Mitochondrial DNA mutation detection in tumors and circulating extracellular vesicles of triple negative breast cancer patients for biomarker development.
Session Title: Poster Session 3
Session Date/Time: Thursday, December 7, 12 - 2 PM
Session Location: Halls 2-3
Kunwar Vikramdeo, Shashi Anand, Sarabjeet Sudan, Paramahansa Pramanik, Seema Singh, Andrew Godwin, Ajay Singh, Santanu Dasgupta
How to treat small triple negative breast cancer
Session Title: Clinical Controversies
Session Date/Time: Thursday, December 7, 2 - 3 PM
Session Location: Stars at Night Ballroom 3-4
Priyanka Sharma and Alexandra ThomasDecember 8, 2023
PS16-09 Analysis of the Radiosensitivity Index/Genomic-Adjusted Radiation Dose (RSI-GARD) in paired pre- and post-treatment TNBC samples: Implications for biomarker-guided radiotherapy
Session Title: Concurrent Poster Spotlight Sessions Block 6, PS16 Enhancing Immunotherapy for Triple Negative Breast Cancer: Novel Therapies and Biomarkers
Session Date/Time: Friday, December 8, 7 - 8 AM
Session Location: Stars at Night Ballroom 3-4
Shane R. Stecklein, Julia White, Rachel Yoder, Joshua Staley, Zachary Schmitt, Anne O'Dea, Lauren Nye, Deepti Satelli, Gregory Crane, Rashna Madan, Maura O'Neil, Andrew Godwin, Harsh Pathak, Qamar Khan, Joyce O'Shaughnessy, Priyanka Sharma
PS16-07 Tumor infiltrating lymphocyte stratification refines AJCC TNM staging based outcomes of early-stage triple negative breast cancer treated with neoadjuvant anthracycline-free, docetaxel and carboplatin chemotherapy.
Session Title: Concurrent Poster Spotlight Sessions Block 6, PS16 Enhancing Immunotherapy for Triple Negative Breast Cancer: Novel Therapies and Biomarkers
Session Date/Time: Friday, December 8, 7 - 8 AM
Session Location: Stars at Night Ballroom 3-4
Miguel Martín, Rachel Yoder, Roberto Salgado, María del MonteMillán, Enrique Álvarez, Isabel Echavarria, Joshua Staley, Coralia Bueno-Muiño, Yolanda Jerez Gilarranz, Andrew Godwin, María Cebollero, Oscar Bueno, José Ángel García-Sáenz, Fernando Moreno Antón, Uriel Bohn, Henry L Gómez, Tatiana Massarrah, Sara López-Tarruella, Priyanka Sharma
PO5-14-01 Weight loss and omega-3 polyunsaturated fatty acid intervention in overweight and obese peri- and postmenopausal women with increased breast cancer risk modifies the gut microbiome and is associated with circulating biomarkers.
Session Title: Poster Session 5
Session Date/Time: Friday, December 8, 12 - 2 PM
Session Location: Halls 2-3
Cook KL, Fabian CJ, Wilson AS, Soto-Pantoja DR, Phillips T, Giles ED, Hursting SD, Umar S, Befort C, Kimler BF -
*The below content was pulled from currently available information on ASTRO's website as well as supplied by KU Cancer Center members.
October 2, 2023
Towards clinical proton minibeam radiation therapy (pMBRT): development of clinical pMBRT system prototype and pMBRT-specific treatment planning method
Scientific Session Title: SS 12 - Phys 3: FLASH and Novel Techniques
Session Date/Time: October 2, 3:30 PM - 3:37 PM
Session Location: Room 30 A/B/C
H. Gao, Y. Lin, W. Zhang, Y. Prezado, E. Traneus, D. Johnson, W. Li, G. N. Gan, and R. C. Chen
*Hao Gao, PhD has been awarded the ASTRO 2023 Basic/Translational Science Award (Senior Investigator, Physics) for this abstract. More information here.October 3, 2023
Hypofractionation for Regional Nodal Irradiation: Investigational Only
Scientific Session Title: EDU 18 - Hypofractionation for Regional Nodal Irradiation: Standard of Care or Investigational Only?
Session Date/Time: October 3, 8:17 AM - 8:32 AM
Session Location: Room 6B
Julia White
SEA-Net: Structure-Enhanced Attention Network for Limited-Angle CBCT Reconstruction of Clinical Projection Data
Scientific Session Title: QP 08 - Phys 5: Motion and Imaging
Session Date/Time: October 3, 8:20 AM - 8:25 AM
Session Location: Room 8
D. Hu, Y. Zhang, W. Li, W. Zhang, K. Reddy, Y. Chen and H. Gao
Proton LET optimization via iterative convex relaxation method
Scientific Session Title: QP 13 - Phys 7: FLASH and Novel Delivery
Session Date/Time: October 3, 4:20 PM - 4:25 PM
Session Location: Room 7
W. Li, Y. Lin, H. Li, R. Rotondo and H. Gao
Investigating the role of MK2 in Head and Neck Squamous Cell Carcinoma growth, metastasis and STING pathway activation
Scientific Session Title: Bio 7: Adaptive Immunity and Radiation
Session Date/Time: October 3, 5:15 PM - 6:15 PM
Deri Morgan, Colby Spiess, Grace Millington, Alyssa Schmidt, Hanna Smith, Dakota Okwuone, Kiersten Berggren, Christopher Lominska, Mary Markiewicz, Tonia Yelder, Hao Gao, Jingxin Wang, Gregory Gan
Medical Student Survey of ASCO Sponsored Oncology Interest Groups in the United States Demonstrates Lack of Education in Radiation Oncology and Negative Perceptions of Future Employment Prospects
Scientific Session Title: PQA 08 - Poster Q&A 08 - Gynecological Cancer, Pediatric Cancer, and Professional Development
Session Date/Time: October 3, 5:15 PM - 6:15 PM
Session Location: Hall B2
Andrew Hoover
Correlation of Post-Treatment Biopsy and Fluorodeoxyglucose PET/CT Findings Following Definitive Chemotherapy and Radiation for Cervical Cancer
Scientific Session Title: PQA 08 - Poster Q&A 08 - Gynecological Cancer, Pediatric Cancer, and Professional Development
Session Date/Time: October 3, 5:15 PM - 6:15 PM
Session Location: Hall B2
Andrew Hoover
October 4, 2023
EDU 39 - Microbiome to Phageome: Clinical and Biological Impact on Precision Radiation
Scientific Session Title: Bio 7: Adaptive Immunity and Radiation
Session Date/Time: October 4, 8:00 AM - 9:00 AM
Session Location: Room 30 A/B/C
Moderators: Subhrajit Saha and Gregory Gan
A new treatment planning method for efficient proton ARC therapy with direct minimization of number of energy jumps.
Scientific Session Title: PQA 10 - Poster Q&A 10 - Physics
Session Date/Time: October 4, 12:30 PM - 1:45 PM
Session Location: Hall B2
G. Zhang, H. Shen, Y. Long, Y. Lin, R. C. Chen and H. Gao
Virtual-collimator based spatial dose modulation for proton GRID therapy.
Scientific Session Title: PQA 10 - Poster Q&A 10 - Physics
Session Date/Time: October 4, 12:30 PM - 1:45 PM
Session Location: Hall B2
W. Zhang, E. Traneus, Y. Lin, G. N. Gan, R. C. Chen and H. GaoAbstract / Poster Only
Sarcopenia As A Predictor For Poor Tolerance to Chemotherapy during Definitive Treatment of Primary Anal Squamous Cell Carcinoma
Andrew Hoover
An effective dose rate optimization algorithm for efficient conventional-dose-rate proton therapy and ultra-high-dose-rate FLASH proton therapy
Y. Zhu, X. Zhang, Y. Lin, C. Lominska and H. Gao
Proton LET optimization via iterative convex relaxation method
W. Li, Y. Lin, H. Li, R. Rotondo and H. Gao
Vertex position optimization for LATTICE therapy
W. Zhang, Y. Lin, F. Wang, R. K. Badkul, R. C. Chen and H. Gao
2V-CBCT: two-orthogonal-projection based CBCT reconstruction and dose calculation from real CBCT projection data
Y. Zhang, D. Hu, W. Li, W. Zhang, R. C. Chen, Y. Chen and H. Gao -
*The below content was pulled from currently available information on ASCO's website as well as supplied by KU Cancer Center members.
June 2, 2023
Differential impact of proliferation signature on efficacy of neoadjuvant chemoimmunotherapy in sTIL-high and sTIL-low triple-negative breast cancer (TNBC): Biomarker analysis of the NeoPACT trial.
2:45 – 5:45 p.m.
Hall D1, Livestream
Oral Abstract Session
Session Title: Breast Cancer – Local/Regional/Adjuvant
Track: Breast Cancer
Shane Stecklein
June 3, 2023
Nutrient Signaling and Multimodality Approaches for Cancer Cachexia
8 – 9:15 a.m.
E451, On Demand
Education Session
Session Title: Current Therapeutic Targets in Cancer Cachexia: A Pathophysiologic Approach
Track: Symptoms and Survivorship | Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary | Lung Cancer
Jill Hamilton-Reeves
A phase 1/2 study of combination olaparib and radium-223 in men with metastatic castration-resistant prostate cancer with bone metastases (COMRADE): A trial in progress.
8 – 11 a.m.
Hall A, On Demand
Poster Session
Session Title: Genitourinary Cancer—Prostate, Testicular, and Penile
Track: Genitourinary Cancer—Prostate, Testicular, and Penile; Sub Track: Prostate Cancer - Advanced/Castrate-Resistant
Abstract #TPS5110; Poster Bd #198a
Chinmay Jani, Wanling Xie, Archana Ajmera, Arlene Araneta, Christina Jamieson, Edmund Folefac, Arif Hussain, Christos Kyriakopoulos, Adam Olson, Mamta Parikh, Rahul Parikh, Biren Saraiya, Salma Jabbour, S. Percy Ivy, Eliezer Van Allen, Neal Lindeman, Bose Kochupurakkal, Geoffrey Shapiro, Rana McKay
MAIN-CAV: Phase III randomized trial of maintenance cabozantinib and avelumab versus avelumab after first-line platinum-based chemotherapy in patients (pts) with metastatic urothelial cancer (mUC; Alliance A032001).
8 – 11 a.m.
Hall A, On Demand
Poster Session
Session Title: Genitourinary Cancer—Kidney and Bladder
Track: Genitourinary Cancer—Kidney and Bladder; Sub Track: Urothelial Cancer - Advanced/Metastatic Disease
Abstract #TPS4609; Poster Bd #97a
Shilpa Gupta, Karla Ballman, Matt Galsky, Michael Morris, Srikala Sridhar, Ronald Chen, Timothy Chan, Yujia Wen, Petros Grivas, Alan Tan, Shiva Baghaie, Jonathan Rosenberg
ETCTN/NCI 10330: A phase 2 study of belinostat with SGI-110 (guadecitabine) or ASTX727 (decitabine/cedazuridine) for the treatment of unresectable and metastatic conventional chondrosarcoma.
1:15 – 4:15 p.m.
Hall A, On Demand
Poster Session
Session Title: Sarcoma
Track: Sarcoma; Sub Track: Bone Tumors
Abstract #11531; Poster Bd #465
Kristine Lacuna, Shing Lee, Liner Ge, Mihaela Druta, Anthony Conley, Mary Louise Keohan, Mark Agulnik, Melissa Burgess, Anna Chalmers, Gina D'Amato, Benjamin Powers, Mahesh Seetharam, Brittany Siontis, Mia Weiss, Sminu Bose, Tahir Sheikh, Richard Piekarz, Gary Schwartz, Matthew Ingham
Patient navigation for lung cancer screening in an urban safety-net system: A pragmatic randomized clinical trial.
1:15 – 4:15 p.m.
Hall A, On Demand
Poster Session
Session Title: Prevention, Risk Reduction, and Hereditary Cancer
Track: Prevention, Risk Reduction, and Hereditary Cancer; Sub Track: Cancer Prevention
Abstract #10577; Poster Bd #210
Sheena Bhalla, Vijaya Natchimuthu, Jessica Lee, Urooj Wahid, Hong Zhu, Noel Santini, Travis Browning, Heidi Hamann, David Johnson, Hsienchang Chiu, Simon Lee, David Gerber
Real-world outcomes and safety in patients with VHL associated tumors receiving belzutifan.
4:30 – 6 p.m.
S102, On Demand
Poster Discussion Session
Session Title: Prevention, Risk Reduction, and Hereditary Cancer
Track: Prevention, Risk Reduction, and Hereditary Cancer; Sub Track: Hereditary Cancer Syndromes
Abstract #10515; Poster Bd #148
Anusha Chidharla, Ryan Fleer, Madison Murphy, Kelly Brunk, Jeffrey Holzbeierlein, Anup Kasi, Rahul Parikh
A phase II basket trial of dual anti–CTLA-4 and anti–PD-1 blockade in rare tumors (DART) SWOG S1609: The desmoid tumors (cohort 27).
4:30 – 6 p.m.
S404, On Demand
Poster Discussion Session
Session Title: Sarcoma
Track: Sarcoma; Sub Track: Soft Tissue Tumors
Abstract #11516; Poster Bd #450
Young Kwang Chae, Megan Othus, Sandip Patel, Benjamin Powers, Chung-Tsen Hsueh, Rangaswamy Govindarajan, Silvana Bucur, Liam Il-Young Chung, Christine
June 4, 2023
A phase II basket trial of dual anti–CTLA-4 and anti–PD-1 blockade in rare tumors (DART SWOG 1609) in patients with refractory gallbladder cancer (cohort 48).
8 – 11 a.m.
Hall A, On Demand
Publication Only
Session Title: Publication Only: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary
Track: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary; Sub Track: Other GI Cancer
Abstract #e16330
Sandip Patel, Elizabeth Guadarrama, Young Kwang Chae, Chih-Yi Liao, Anup Kasi, Grace Tarabay, Thomas George, Liam Chung, Gabby Lopez, Christine McLeod, Megan Othus, Helen Chen, Elad Sharon, Howard Streicher, Christopher Ryan, Charles Blanke, Razelle KurzrockExtracellular vesicle-derived non-coding RNAs to predict outcome in patients with triple-negative breast cancer (TNBC) with residual disease (RD).
8 – 11 a.m.
Hall A, On Demand
Poster Session
Session Title: Breast Cancer—Local/Regional/Adjuvant
Track: Breast Cancer; Sub Track: Biologic Correlates
Abstract #578; Poster Bd #408
Shane Stecklein, Devin Koestler, Nanda Yellapu, Rachel Yoder, Bruce Kimler, Joshua Staley, Zachary Schmitt, Qamar Khan, Anne O'Dea, Lauren Nye, Manana Elia, Jaimie Heldstab, Trisha Home, Stephen Hyter, Kamilla Isakova, Harsh Pathak, Andrew Godwin, Priyanka SharmaNRG-BR007: A phase III trial evaluating de-escalation of breast radiation (DEBRA) following breast-conserving surgery (BCS) of stage 1, HR+, HER2-, RS ≤18 breast cancer.
8 – 11 a.m.
Hall A, On Demand
Poster Session
Session Title: Breast Cancer—Local/Regional/Adjuvant
Track: Breast Cancer; Sub Track: Local-Regional Therapy
Abstract #TPS623; Poster Bd #449a
Julia White, Reena Cecchini, Eleanor Harris, Eleftherios Mamounas, Daniel Stover, Patricia Ganz, Reshma Jagsi, Stewart Anderson, Carmen Bergom, Valerie Theberge, Mahmoud El-Tamer, Richard Zellars, Dean Shumway, Guang-Pei Chen, Thomas Julian, Norman Wolmark, Annabel Goodwin
Clinical validation of an activity-based enzyme assay for early stage lung cancer.
8 – 11 a.m.
Hall A, On Demand
Poster Session
Session Title: Lung Cancer—Non-Small Cell Local-Regional/Small Cell/Other Thoracic Cancers
Track: Lung Cancer; Sub Track: Biologic Correlates
Abstract #8533; Poster Bd #160
Paul Dempsey, Cristina-Mihaela Aparicio, Ricardo Gonzalezirias, Spencer Hantula, Mari Kagawa, Stefan Bossmann, Obdulia Covarrubias-Zambrano, Alykhan Nagji, Nirmal Veeramachaneni, Nezih Ermerak, Derya Kocakaya, Tunc Lacin, Bedrettin Yildizeli, Sara Witting Christensen Wen, Line Nederby, Torben Hansen, Ole Hilberg
Comparing the prognostic and predictive utility of serum thymidine kinase 1 and CA 15-3 in patients with hormone receptor positive metastatic breast cancer starting first-line endocrine therapy in SWOG S0226.
8 – 11 a.m.
Hall A, On Demand
Poster Session
Session Title: Breast Cancer—Metastatic
Track: Breast Cancer; Sub Track: Hormone Receptor-Positive
Abstract #1076; Poster Bd #297
Erin Cobain, William Barlow, Costanza Paoletti, Mattias Bergqvist, Amy Williams, Hanna Ritzen, Rita Mehta, Julie Gralow, Gabriel Hortobagyi, Kathy Albain, Lajos Pusztai, Priyanka Sharma, Andrew Godwin, Alastair Thompson, Daniel Hayes, James RaeHow PROMs Can Reveal More About Patient Buy-in to Therapy
11:30 a.m. – 12:45 p.m.
S100bc, On Demand
Education Session
Session Title: Patient-Centric Clinical Trial Design in Genitourinary Cancers: Meaningful Endpoints, Assessments, and Outcome Measures
Track: Genitourinary Cancer—Kidney and Bladder | Clinical Trials
Elizabeth Wulff-BurchfieldJune 5, 2023
Effect of a telephone-based weight loss intervention (WLI) on weight at 12-months in women with early breast cancer: Results from the Breast Cancer Weight Loss (BWEL) trial.
8 – 11 a.m.
S100a, Livestream
Oral Abstract Session
Session Title: Symptoms and Survivorship
Track: Symptoms and Survivorship; Sub Track: Health Promotion
Abstract #12001
Jennifer Ligibel, Karla Ballman, Linda McCall, Pamela Goodwin, Anna Weiss, Linda Delahanty, Catherine Alfano, Tracy Crane, Marian Neuhouser, Patricia Spears, Dawn Hershman, Electra Paskett, Judith Hopkins, Vanessa Bernstein, Vered Stearns, Julia White, Thomas Wadden, Eric Winer, Ann Partridge, Lisa CareyA multi-cohort phase I/IIa clinical trial to evaluate the safety, tolerability, and pharmacokinetics of TST001 administered as a monotherapy, with nivolumab or standard of care in patients with locally advanced or metastatic solid tumors: TransStar101.
8 – 11 a.m.
Hall A, On Demand
Poster Session
Session Title: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary
Track: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary; Sub Track: Esophageal or Gastric Cancer - Advanced/Metastatic Disease
Abstract #TPS4176; Poster Bd #494b
Yelena Janjigian, Weijing Sun, Caio Max Rocha Lima, Satish Shah, Aaron Scott, Dulabh Monga, Madappa Kundranda, Amna Sher, Philip Gold, Jordan Berlin, Manish Patel, Olatunji Alese, Erika Hamilton, Michael Cecchini, Brian Van Tine, Ben George, Rutika Mehta, Zhenzhong Xia, Caroline Germa, Nashat Gabrail
Effectiveness of a cardiovascular health EHR application for cancer survivors in community oncology practice: Results from WF-1804CD.
8 – 11 a.m.
S100a, Livestream
Oral Abstract Session
Session Title: Symptoms and Survivorship
Track: Symptoms and Survivorship; Sub Track: Health Promotion
Abstract #LBA12007
Kathryn Weaver, Emily Dressler, Heidi Klepin, Simon Lee, Sydney Smith, Brian Wells, W. Hundley, Glenn Lesser, Chandylen Nightingale, Alyssa Throckmorton, Marcia Hernandez, Jenny Hanna, Ian Lackey, Kevin Heard, Randi Foraker
KRAS G12C-mutated pancreatic cancer: Clinical outcomes based on chemotherapeutic regimen.
8 – 11 a.m.
Hall A, On Demand
Poster Session
Session Title: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary
Track: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary; Sub Track: Pancreatic Cancer - Advanced/Metastatic Disease
Abstract #4150; Poster Bd #471
Aaron Ciner, Bach Ardalan, Yasmine Baca, Sourat Darabi, Anup Kasi, Emil Lou, Jose Azqueta, Joanne Xiu, Chadi Nabhan, Anthony Shields, Andrew Aguirre, Harshabad Singh, Rachna Shroff, Michael Pishvaian, Sanjay Goel
Apollo: A randomized phase II double-blind study of olaparib versus placebo following curative intent therapy in patients with resected pancreatic cancer and a pathogenic BRCA1, BRCA2, or PALB2 mutation—ECOG-ACRIN EA2192.
8 – 11 a.m.
Hall A, On Demand
Poster Session
Session Title: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary
Track: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary; Sub Track: Pancreatic Cancer - Local-Regional Disease
Abstract #TPS4202; Poster Bd #507b
Kim Reiss, Sung Hong, Anup Kasi, Eileen O'Reilly, Shishir Maithel, Xin Yao, Stanley Hamilton, Ben Boursi, Michael Pishvaian, Samuel Klempner, Susan Domchek, Paul Catalano, E. Gabriela Chiorean, Philip Philip, Peter O'DwyerA phase 2 basket trial of ulixertinib (BVD-523) in combination with hydroxychloroquine in patients with advanced gastrointestinal malignancies harboring MAPK pathway mutations (BVD-523-HCQ).
8 – 11 a.m.
Hall A, On Demand
Poster Session
Session Title: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary
Track: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary; Sub Track: Esophageal or Gastric Cancer - Advanced/Metastatic Disease
Abstract #TPS4174; Poster Bd #493b
Andrew Ko, Mark Zalupski, Raed Al-Rajabi, Khalid Matin, Deirdre Cohen, Smitha Krishnamurthi, Brent Kreider, Jessica Box, Caroline Emery, Martin Teresk, Mary Varterasian, Martin Lee, Anna Groover, Deb Knoerzer, Rachna Shroff
Targeting minimal residual disease (MRD) in resected RAS mutated pancreatic cancer with vaccine TG01/QS-21 +/- PD-1 inhibitor, balstilimab: A randomized phase II study (TESLA).
8 – 11 a.m.
Hall A, On Demand
Poster Session
Session Title: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary
Track: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary; Sub Track: Pancreatic Cancer - Local-Regional Disease
Abstract #: TPS4205; Poster Bd #509a
Anup Kasi, Francisco Diaz, Raed Al-Rajabi, Joaquina Baranda, Erin Carroll, Cathey Belcher, Mojtaba Olyaee, Amit Rastogi, Timothy Schmitt, Sean Kumer, Atta Nawabi, Harsh Pathak, Andrew Godwin, Mary Markiewicz, Weijing Sun
Phase 1B/2A safety, pharmacokinetics and pharmacodynamics study of fosciclopirox alone and in combination with cytarabine in patients with relapsed/refractory acute myeloid leukemia.
8 – 11 a.m.
Hall A, On Demand
Poster Session
Session Title: Hematologic Malignancies—Leukemia, Myelodysplastic Syndromes, and Allotransplant
Track: Hematologic Malignancies; Sub Track: Acute Leukemia
Abstract #TPS7078; Poster Bd #205b
Tara Lin, Robyn Wood, Tammy Ham, Taegen Sullivan, Prasad Dandawate, Shrikant Anant, Marianne Santaguida, Paul Toren, Roy Jensen, John Taylor, Michael Baltezor, Michael Dalton, Fred Meyer, John McBride, Jay Umbreit, William McCulloch, Kathryn Vanderlaag, Joseph Wagner, Scott Weir, B. Smith
Survival outcomes with CPX-351 vs 7+3 by baseline bone marrow blast percentage in older adults with newly diagnosed high-risk or secondary acute myeloid leukemia: A 5-year follow-up study.
8 – 11 a.m.
Hall A, On Demand
Poster Session
Session Title: Hematologic Malignancies—Leukemia, Myelodysplastic Syndromes, and Allotransplant
Track: Hematologic Malignancies; Sub Track: Acute Leukemia
Abstract #7027; Poster Bd #157
Ellen Ritchie, Tara Lin, Laura Newell, Robert Stuart, Scott Solomon, Richard Stone, Gary Schiller, Matthew Wieduwilt, Eileen Ryan, Nalina Dronamraju, Jeffrey Lancet, Jorge Cortes
Cardiotoxicity of CPX-351 vs 7+3 in patients with untreated high-risk acute myeloid leukemia.
8 – 11 a.m.
Hall A, On Demand
Poster Session
Session Title: Hematologic Malignancies—Leukemia, Myelodysplastic Syndromes, and Allotransplant
Track: Hematologic Malignancies; Sub Track: Acute Leukemia
Abstract #: 7029; Poster Bd #159
Joshua Mitchell, Michael Pfeiffer, John Boehmer, John Gorcsan, Nalina Dronamraju, Stefan Faderl, Tara Lin, Geoffrey Uy, Jeffrey Lancet, Jorge CortesRandomized trial of fixed dose capecitabine compared to standard dose capecitabine in metastatic breast cancer: The X-7/7 trial.
11:30 a.m. – 2:30 p.m.
Oral Abstract Session
Session Title: Breast Cancer - Metastatic
Track: Hematologic Malignancies; Sub Track: Acute Leukemia
Abstract #: 1007Qamar J. Khan, Colleen Bohnenkamp, Taylor Monson, Holly Smith, Milind Phadnis, Vinay Raja, Manana Elia, Anne O'Dea, Gregory Crane, Mark Fesen, Lauren Elizabeth Nye, Maureen Sheehan, Robert E. Pluenneke, Raed Al-Rajabi, Joaquina Baranda, Anup Kasi, Richard J. McKittrick, Laura Mitchell, Stephanie LaFaver, Priyanka Sharma
Not all treated KRAS-mutant pancreatic adenocarcinomas are equal: KRAS G12D and survival outcome.
11:30 a.m. – 1 p.m.
Hall D2, Livestream
Poster Discussion Session
Session Title: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary
Track: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary; Sub Track: Pancreatic Cancer - Advanced/Metastatic Disease
Abstract #4020; Poster Bd #341
Bach Ardalan, Aaron Ciner, Yasmine Baca, Sourat Darabi, Anup Kasi, Emil Lou, Jose Azqueta, Joanne Xiu, Chadi Nabhan, Anthony Shields, Andrew Aguirre, Harshabad Singh, Rachna Shroff, Michael Pishvaian, Sanjay GoelDifferential impact of proliferation signature on efficacy of neoadjuvant chemoimmunotherapy in sTIL-high and sTIL-low triple-negative breast cancer (TNBC): Biomarker analysis of the NeoPACT trial.
11:30 a.m. – 2:30 p.m.
Hall B1, Livestream
Oral Abstract Session
Session Title: Breast Cancer—Local/Regional/Adjuvant
Track: Breast Cancer; Sub Track: Biologic Correlates
Abstract #507
Shane Stecklein, Rachel Yoder, Joshua Staley, Zachary Schmitt, Anne O'Dea, Lauren Nye, Manana Elia, Deepti Satelli, Gregory Crane, Rashna Madan, Maura O'Neil, Andrew Godwin, Roberto Salgado, Qamar Khan, Joyce O'Shaughnessy, Priyanka SharmaReal-world early outcomes of axicabtagene ciloleucel for relapsed or refractory (R/R) follicular lymphoma (FL).
1:15 – 2:45 p.m.
E450, On Demand
Poster Discussion Session
Session Title: Hematologic Malignancies—Lymphoma and Chronic Lymphocytic Leukemia
Track: Hematologic Malignancies; Sub Track: Non-Hodgkin Lymphoma
Abstract #7509; Poster Bd #60
Caron Jacobson, Michael Hemmer, Zhen-Huan Hu, Matthew Frank, Leslie Popplewell, Nausheen Ahmed, Yi Lin, Timothy Best, Sara Beygi, Harry Miao, Christine Fu, Fang Sun, Hairong Xu, Marcelo PasquiniDemographic predictors of successful transition to adult survivorship care for survivors of pediatric cancer.
1:15 – 4:15 p.m.
Hall A, On Demand
Poster Session
Session Title: Pediatric Oncology
Track: Pediatric Oncology; Sub Track: Survivorship
Abstract #10050; Poster Bd #356
Renee Gilbert, Carolyn Bates, Kyla Alsman, Joy Fulbright, Becky Lowry, Eve-Lynn Nelson
Objective assessment of fatigue, sleep and insomnia in breast cancer survivors on estrogen deprivation therapy.
1:15 – 4:15 p.m.
Hall A, On Demand
Poster Session
Session Title: Symptoms and Survivorship
Track: Symptoms and Survivorship; Sub Track: Palliative Care and Symptom Management
Abstract #TPS12145; Poster Bd #509a
Lauren Fowler, Jamie Myers, Shelby Re, Maddie Tedrick, Matthew Hudson, Joe Stephenson, Mark O'Rourke
English- and Spanish-preferring patient perspectives on managing acute care needs at two disparate health systems.
1:15 – 4:15 p.m.
Hall A, On Demand
Poster Session
Session Title: Care Delivery and Regulatory Policy
Track: Care Delivery and Regulatory Policy; Sub Track: Care Delivery/Models of Care
Abstract #1524; Poster Bd #118
Beverly Kyalwazi, Ethan Halm, D. Mark Courtney, John Sweetenham, Navid Sadeghi, John Cox, Simon Lee, Arthur Hong
Peripheral blood epigenetic immune-profiling and survival outcomes with anti-programmed death (PD)-1 based therapy in recurrent/metastatic (R/M) squamous cell carcinoma of head and neck (SCCHN).
1:15 – 4:15 p.m.
Hall A, On Demand
Poster Session
Session Title: Head and Neck Cancer
Track: Head and Neck Cancer; Sub Track: Biologic Correlates
Abstract #6062; Poster Bd #54
Kartik Sehgal, Ze Zhang, Keisuke Shirai, Rondi Butler, Min Lee, Annette Molinaro, John Wiencke, Devin Koestler, Lucas Salas, Brock Christensen, Karl Kelsey, Robert HaddadA phase 1 study of belantamab mafodotin in combination with standard of care in newly diagnosed multiple myeloma: An interim analysis of DREAMM-9.
3 – 4:30 p.m.
E450, On Demand
Poster Discussion Session
Session Title: Hematologic Malignancies—Plasma Cell Dyscrasia
Track: Hematologic Malignancies; Sub Track: Multiple Myeloma
Abstract #8018; Poster Bd #10
Saad Usmani, Michał Mielnik, Ja Byun, Aránzazu Alonso Alonso, Al-Ola Abdallah, Mamta Garg, HANG QUACH, Chang-Ki Min, Wojciech Janowski, Enrique Ocio, Katja Weisel, Albert Oriol, Irwindeep Sandhu, Paula Rodríguez-Otero, Karthik Ramasamy, Jacqueline Egger, Danae Williams, Jie Ma, Morrys Kaisermann, Marek HusPolygenic risk score calibration and association with breast cancer in diverse ancestries.
3 – 6 p.m.
S100a, Livestream
Oral Abstract Session
Session Title: Prevention, Risk Reduction, and Hereditary Cancer
Track: Prevention, Risk Reduction, and Hereditary Cancer; Sub Track: Cancer Prevention
Abstract #10505
Matthew Kucera, Elisha Hughes, Brent Mabey, Brooke Hullinger, Holly Pederson, Tuya Pal, Susan Domchek, Charis Eng, Judy Garber, Ora Gordon, Jennifer Klemp, Semanti Mukherjee, Joseph Vijai, Sandhya Pruthi, Allison Kurian, Pat Whitworth, Jerry Lanchbury, Thomas Slavin, Alexander Gutin, Olufunmilayo Olopade
Randomized phase II trial of dabrafenib and trametinib with or without navitoclax in patients (pts) with BRAF-mutant (MT) metastatic melanoma (MM) (CTEP P9466).
3 – 6 p.m.
Hall D1, Livestream
Oral Abstract Session
Session Title: Melanoma/Skin Cancers
Track: Melanoma/Skin Cancers; Sub Track: Advanced/Metastatic Disease
Abstract #9511
Zeynep Eroglu, Janice Mehnert, Anita Giobbie-Hurder, Kari Kendra, Gino In, April Salama, Gary Doolittle, Jeffrey Sosman, Jennifer Valerin, Theresa Medina, Jose Lutzky, Stergios Moschos, Nikhil Khushalani, Joseph Markowitz, Naoko Takebe, Helen Chen, Laura Knight, Michael Davies, Ryan SullivanJune 6, 2023
Real-world outcomes of brexucabtagene autoleucel (brexu-cel) for relapsed or refractory (R/R) mantle cell lymphoma (MCL): A CIBMTR subgroup analysis by prior treatment.
9:45 a.m. – 12:45 p.m.
S100a, Livestream
Oral Abstract Session
Session Title: Hematologic Malignancies—Lymphoma and Chronic Lymphocytic Leukemia
Track: Hematologic Malignancies; Sub Track: Non-Hodgkin Lymphoma
Abstract #7507
Swetha Kambhampati, Nausheen Ahmed, Mehdi Hamadani, Natalie Grover, Mazyar Shadman, Frederick Locke, James Gerson, Matthew Frank, Lihua Budde, Michael Wang, Zhen-Huan Hu, Ana Nunes, David Dalton, Ioana Kloos, Daniel Lee, Hairong Xu, Marcelo Pasquini, Alex HerreraPublication Only
Energetics and Lifestyle in Inherited Syndromes (ELLIES Project): Feasibility of remote specimen collection for biomarker analysis.
Session Title: Publication Only: Prevention, Risk Reduction, and Hereditary Cancer
Track: Prevention, Risk Reduction, and Hereditary Cancer; Sub Track: Hereditary Cancer Syndromes
Abstract #e22545
Priyanka Venkatesh, Catherine Knight, Jennifer Klemp, Rajni Puri, Harsh Pathak, Clark Bloomer, Lauren NyeEfficacy of teclistamab in patients (pts) with heavily pretreated, relapsed/refractory multiple myeloma (RRMM), including those refractory to penta RRMM and BCMA (B-cell maturation antigen) directed therapy (BDT).
Session Title: Publication Only: Hematologic Malignancies—Plasma Cell Dyscrasia
Track: Hematologic Malignancies; Sub Track: Multiple Myeloma
Abstract #e20044
Priyanka Venkatesh, Shebli Atrash, Barry Paul, Omar Alkharabsheh, Aimaz Afrough, Zahra Mahmoudjafari, Muhammad Umair Mushtaq, Hamza Hashmi, James Davis, Al-Ola Abdallah
Rural communities and health professional shortage areas (HPSA) and access to immune effector cellular therapy and lymphoma/myeloma clinical trials.
Session Title: Publication Only: Health Services Research and Quality Improvement
Track: Health Services Research and Quality Improvement; Sub Track: Healthcare Equity/Access to Care
Abstract #e18633
Nausheen Ahmed, William Wesson, Dinesh Pal Mudaranthakam, Muhammad Umair Mushtaq, Al-Ola Abdallah, Forat Lutfi, Joaquina Baranda, Sunil Abhyankar, Joseph McGuirk, Marc Hoffmann
Responses in patients with AML and treated with entospletinib monotherapy.
Session Title: Publication Only: Hematologic Malignancies—Leukemia, Myelodysplastic Syndromes, and Allotransplant
Track: Hematologic Malignancies; Sub Track: Acute Leukemia
Abstract #e19010
Tara Lin, Richard Cutler, Elizabeth Olek, Luis Carvajal, Jorge DiMartino, Alison Walker
Pharmacokinetics (PK) of epacadostat in combination with sirolimus in advanced malignancy.
Session Title: Publication Only: Developmental Therapeutics—Immunotherapy
Track: Developmental Therapeutics—Immunotherapy; Sub Track: New Targets and New Technologies (IO)
Abstract #e14589
Chao Huang, Takefumi Komiya, Anup Kasi, Stephen Williamson, Scott Weir, Joaquina Baranda
Dares: A phase II trial of durvalumab and ablative radiation in extensive stage small cell lung cancer.
Poster Session
Session Title: Lung Cancer—Non-Small Cell Local-Regional/Small Cell/Other Thoracic Cancers
Track: Lung Cancer; Sub Track: Small Cell Lung Cancer
Abstract #TPS8615; Poster Bd #234a
Aditya Juloori, Gregory Gan, Jun Zhang, Mohamed Abazeed, Jared Hara, Andrew Baschnagel, Anne Traynor, Michael Bassetti, Marina Garassino, Jyoti Patel, Steven Chmura, Christine Bestvina
Effect of durable hematocrit control and minimal thrombotic risk in real-world polycythemia vera patients treated with ruxolitinib.
Session Title: Publication Only: Hematologic Malignancies—Leukemia, Myelodysplastic Syndromes, and Allotransplant
Track: Hematologic Malignancies; Sub Track: Myeloproliferative Syndromes (MPD)
Abstract #e19080
Aleksander Chojecki, Danielle Boselli, Allison Dortilus, Issam Hamadeh, Stephanie Begley, Tommy Chen, Rupali Bose, Nikolai Podoltsev, Amer Zeidan, Nicole Balmaceda, Abdulraheem Yacoub, Jing Ai, Thomas Knight, Brittany Ragon, Nilay Shah, Srinivasa Sanikommu, James Symanowski, Ruben Mesa, Michael Grunwald
Circulating tumor cells (CTCs) dynamics after CDK4/6i for hormone-receptor positive (HR+) metastatic breast cancer (MBC): A biomarker analysis of the PACE randomized phase II study.
Poster Session
Session Title: Breast Cancer—Metastatic
Track: Breast Cancer; Sub Track: Hormone Receptor-Positive
Abstract #1059; Poster Bd #280
Lorenzo Gerratana, Yue Ren, Carolina Reduzzi, Meredith Regan, Reshma Mahtani, Cynthia Ma, Angela DeMichele, Jane Meisel, Kathy Miller, Trevor Jolly, Elizabeth Riley, Rubina Qamar, Priyanka Sharma, Sonya Reid, Naomi Ko, Yuan Liu, Harold Burstein, Sara Tolaney, Massimo Cristofanilli, Erica Mayer
Targeting germline or somatic DNA repair defects (beyond BRCA) in pancreatic cancer with niraparib: A phase II study (NIRA-PANC).
Poster Session
Session Title: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary
Track: Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary; Sub Track: Pancreatic Cancer - Advanced/Metastatic Disease
Abstract #4156; Poster Bd #477
Anup Kasi, Junqiang Dai, Raed Al-Rajabi, Joaquina Baranda, Anwaar Saeed, Prabhakar Chalise, Erin Carroll, Shannon Bradbury, Stephen Hyter, Malgorzata Witek, Venkatadri Beeki, Richard McKittrick, Manidhar Reddy Lekkala, Anusha Chidharla, Sean Kumer, Timothy Schmitt, Stephen Williamson, Steven Soper, Andrew Godwin, Weijing Sun -
Underline: KUCC Members
Underline & Bold: KUCC Members that PresentedApril 16, 2023
SESSION PO.ET01.01 - Oncogenes and Tumor Suppressor Genes as Targets for Therapy 1
536 / 3 - The role of CCN1 in mutant K-RAS addiction in pancreatic ductal adenocarcinoma
1:30 - 5 p.m.
Archana De, Vijayalaxmi Gupta, Amlan Das, Arnab Ghosh, Inamul Haque, Laster Lau, Sushanta K. Banerjee, Snigdha BanerjeeSESSION PO.MCB05.01 - Targeting Replication Stress and the Immune Microenvironment
302 / 4 - Loss of head and neck squamous cell carcinoma MK2 increases STING activation through increased micronuclei formation
1:30 - 5 p.m.
Colby Spiess, Grace Millington, Hannah Smith, Dakota D. D. Okwuone, Kiersten Berggren, Deri Morgan, Chris Lominska, Sufi M. Thomas, Jingxin Wang, Mary Markiewicz, Gregory N. GanSESSION PO.MCB08.05 - Innovative Approaches for Tumor Profiling and Data Analysis 2
243 / 7 - Long-read sequencing of pediatric cancer genomes identifies multiple clinically relevant variants
1:30 - 5 p.m.
Byunggil Yoo, Warren Cheung, Irina Pushel, Lisa Lansdon, Chengpeng Bi, Erin Guest, Tomi Pastinen, Midhat Farooqi
SESSION CTPL02 - Hope for Rare Cancers: Novel Targeted and Immunotherapy Agents
CT009 - S1512: High response rate with single agent anti-PD-1 in patients with metastatic desmoplastic melanoma
5 – 5:15 p.m.
Kari Kendra, Shay Bellasea, Zeynep Eroglu, Siwen Hu-Lieskovan, Katie M. Campbell, William Carson III, David Wada, Jose A. Plaza, Jeffrey Sosman, Gino K. IN, Alexandra Ikeguchi, John Hyngstrom, Andres Brohl, Nikhil I. Khushalani, Joseph Markowitz, George Negrea, Samer Kasbari, Gary C. Doolittle, Umang Swami, Toni Roberts, Sapna P. Patel, Elad Sharon, James Moon, Michael C. Wu, Antoni Ribas.April 17, 2023
SESSION PO.CL01.11 - Biomarkers for Elucidation of Tumor Biology and Metastasis
2119 / 22 - Intravenous vitamin C therapy for cisplatin ineligible bladder cancer patients (CI-MIBC): Early investigation into potential pharmacodynamic biomarkers
9 a.m. – 12:30 p.m.
Benjamin L. Woolbright, Ganeshkumar Rajendran, Erika Abbott, Zeb Zacharias, Jon Houtman, Rahul Parikh, Qi Chen, Ameer Hamza, Elizabeth Wulff-Burchfield, Jeffrey M. Holzbeierlein, Jeanne Drisko, Michael D. Henry, John A. TaylorSESSION PO.CT03.01 - Phase III and Pediatric Clinical Trials
CT089 / 17 - Molecular-guided therapy for the treatment of patients with relapsed and refractory childhood cancers: a Beat Childhood Cancer Research Consortium trial
9 a.m. – 12:30 p.m.
Giselle L. Saulner Sholler, Jacqueline Kraveka, Genevieve Bergendahl, Elizabeth Lewis, William Ferguson, Abhinav Nagulapally, Karl Dykema, Valerie Brown, Michael Isakoff, Joseph Junewick, Deanna Mitchell, Don Eslin, Virginia Harrod, William Roberts, Javier Oesterheld, Randy Wada, Jawhar Rawwas, Devang Pastakia, Kevin Ginn, Raya Saab, Kevin Bielamowicz, Jason Glover, Eugenia Chang, Gina Hanna, Daniel Enriquez, Tyler Izatt, Rebecca Halperin, Sara Byron, William Hendricks, Jeffrey Trent.SESSION PO.ET01.02 - Oncogenes and Tumor Suppressor Genes as Targets for Therapy 2
1706 / 3 - A non-canonical MiT/TFE-dependent NRF2 program is a druggable vulnerability in multiple cancer types
9 a.m. – 12:30 p.m.
Xinbo Luo, Bart Lutterbach, Priya Pancholi, Yeon Sook Choi, Xiao Liu, Phillip Munson, Saqib Faisal, David A. Whipple, Robert A. Smith, Warren S. Weiner, David K. Johnson, Myriam Boukhali, Nicole S. Persky, Matthew G. Rees, Shunsuke Kitajima, David Barbie, Anuradha Roy, Michael Baltezor, Lian Rajewski, William McGuinness6, John Haslam, Ananthan Sadagopan, Charles H. Yoon, Cory M. Johannessen, Christine G. Lian7, Jason L. Hornick7, Srinivas R. Viswanathan, David Liu, Vicki Nienaber, Wilhelm Haas, Frank J. Schoenen, David E. Fisher, Rizwan Haq
SESSION PO.ET02.03 - New Therapeutic Targeted Agents
1585 / 8 - Targeting acid ceramidase-1 to inhibit sphingolipid metabolism and tumor growth in pancreatic ductal carcinoma
9 a.m. – 12:30 p.m.
Krishan G. Jain, Hindole Ghosh, Sangita Bhattacharyya, Anup Kasi, Ameer Hamza, Scott J. Weir, Michael VanSaun, Stefan Bossmann, Shrikant Anant, Bernhard Biersack, Prasad R. Dandawate
SESSION PO.ET03.06 - Reversal of Drug Resistance
1753 / 18 - Functional inhibition of the RNA-binding protein HuR sensitizes triple-negative breast cancer to chemotherapy
9 a.m. – 12:30 p.m.
Lanjing Wei, Qi Zhang, Cuncong Zhong, Jeffrey Aubé, Danny Welch, Xiaoqing Wu, Liang Xu
SESSION PO.ET05.01 - Cell Cycle/Cell Proliferation Inhibitors for Cancer Therapy
1565 / 13 - Targeting of KIF11 and AURKA to improve outcomes in Ewing sarcoma
9 a.m. – 12:30 p.m.
Soumya M. Turaga, Vikalp Vishwakarma, Stacey Hembruff, Rajni Puri, Priya Sabu, Glenson Samuel, Andrew K. Godwin
SESSION PO.MCB02.02 - Autophagy, Mitochondrial Function, and Ferroptosis
1370 / 1 - Overexpression of the small GTPase Rab27B regulates autophagy flux and contributes to tumor growth in colorectal cancer
9 a.m. – 12:30 p.m.
Sahida Afroz, Ranjan Preet, Vikalp Vishwakarma, Dan A. Dixon
SESSION LBPO.CL01 - Late-Breaking Research: Clinical Research 1 / Endocrinology
LB122 / 5 - Arima-HiC sequencing accurately detects clinically relevant structural variants in pediatric leukemia samples
1:30 – 5 p.m.
Anthony Schmitt, Shadi Melnyk, Kristin Sikkink, Lisa Lansdon, Tomi Pastinen, Erin Guest, Midhat Farooqi
SESSION PO.CL01.08 - Diagnostic and Prognostic Biomarkers 3
3301 / 9 - Ultrasensitive compartment-free digital phenotyping of circulating extracellular vesicles for diagnosis of Ewing sarcoma
1:30 – 5 p.m.
Yunjie Wen, Vikalp Vishwakarma, Andrew K. Godwin, Yong ZengSESSION PO.CL01.10 - Early Detection Biomarkers
3351 / 26 - Identification of novel biomarkers for high grade serous ovarian cancer screening via extracellular vesicle proteomic profiling
1:30 – 5 p.m.
Camille V. Trinidad, Harsh B. Pathak, Shibo Cheng, Rashna Madan, Mihaela E. Sardiu, Leonidas E. Bantis, Yong Zeng, Andrew K. Godwin
3354 / 29 - Isolation and characterization of circulating tumor cells from ductal carcinoma in situ patients using label free technology
Brittany Rupp, Brooke Thanasiu, Neha Nagpal, Yan Hong, Dean E. Brenner, Kirsten Tuck, Kirk Herman, Fariba Behbod, Justin Colacino, Max Wicha, Sunitha Nagrath
SESSION PO.CL07.07 - Combination Immunotherapies 2
3275 / 16 - Combination of talimogene laherparepvec (T-VEC) with pembrolizumab (pembro) in advanced melanoma patients following progression on a prior PD-1 inhibitor: SWOG S1607
1:30 – 5 p.m.
Siwen Hu-Lieskovan, James Moon, John Hyngstrom, Katie M. Campbell, Gino K. In, Theodore F. Logan, Kari L. Kendra, Ding M. Wang, Douglas B. Johnson, Gary C. Doolittle, Alan Tan, Ann W. Silk, Kenneth F. Grossmann, Christopher W. Ryan, Sapna P. Patel, Shay Bellasea, Michael C. Wu, John M. Kirkwood, Helen X. Chen, Antoni Ribas
SESSION PO.CL07.11 - Combination Immunotherapies 1
3235 / 8 - Protein kinase C is an upstream regulator of IL13Ra2 and small molecular activator enhances CAR T mediated killing
1:30 – 5 p.m.
Siddharth Subham, John D. Jeppson, Bryan Schatmeyer, Stephen J. Forman, Christine E. Brown, David Akhavan
SESSION PO.CT02.01 - Phase II Clinical Trials 1
CT167 / 29 - Efficacy of pirtobrutinib, a highly selective, non-covalent (reversible) BTK inhibitor in Richter transformation: Results from the phase 1/2 BRUIN study
1:30 – 5 p.m.
Joanna Rhodes, David Lewis, Paolo Ghia, Nirav N. Shah, Catherine C. Coombs, Chan Y. Cheah, Jennifer Woyach, Nicole Lamanna, Marc S. Hoffmann, Shuo Ma, Toby A. Eyre, Talha Munir, Manish R. Patel, Alvaro J. Alencar, Constantine S. Tam, John F. Seymour, Wojciech Jurczak, Ewa Lech-Maranda, Lindsey E. Roeker, Philip A. Thompson, Paolo B. Abada, Chunxiao Wang, Binoj Nair, Hui Liu, Donald E. Tsai, Anthony R. Mato, William G. Wierda.
SESSION PO.ET02.07 - Drug Delivery Systems
2701 / 4 - pH-responsive targeted-nanoparticle releases encapsulated ERK-inhibitor effectively in the hypoxic microenvironment and sensitizes gemcitabine in pancreatic cancer cells
1:30 – 5 p.m.
Debasmita Dutta, Archana De, Raj Shankar Hazra, Pratyusha Ghosh, Mohiuddin Quadir, Snigdha Banerjee, Sushanta K. Banerjee
SESSION PO.PR01.03 - Biological and Behavioral Factors in Cancer Surveillance, Prevention, and Survivorship
3030 / 2 - Effect of 6 months of bazedoxifene and conjugated estrogen on measures of insulin resistance in postmenopausal women at increased risk for breast cancer
1:30 – 5 p.m.
Carol J. Fabian, Erin D. Giles, Katherine L. Cook, Kandy Powers, Christy Altman, Amy Kreutzjans, Teresa Phillips, Adrian Zelenchuk, Krystal Pittman, Stephen D. Hursting, Bruce Kimler
SESSION PO.PS01.03 - Aging, Immune Factors, and Metabolomics
3005 / 1 - Pre-diagnostic methylation-based leukocyte profiles and non-small cell lung cancer risk in heavy smokers
1:30 – 5 p.m.
Laurie Grieshober, Stefan Graw, Matt J. Barnett, Gary E. Goodman, Chu Chen, Devin C. Koestler, Carmen J. Marsit, Jennifer A. DohertyApril 18, 2023
SESSION ADT10 - Dharma Master Jiantai Advances in Biomarkers Session: Next Generation Technologies and Biomarkers for the Early Detection of Cancer10:15 – 11:45 a.m.Location: Tangerine Ballroom 1, Convention CenterChairperson: Andrew K. GodwinSESSION PO.BCS02.04 - Integrative Cancer Systems Biology
4318 / 16 - Cancer cell communication with macrophages prevents T cell activation during emergence of cell cycle therapy resistance
9 a.m. – 12:30 p.m.
Jason I. Griffiths, Patrick A. Cosgrove, Eric Medina Castaneda, Aritro Nath, Jinfeng Chen, Frederick R. Adler, Jeffrey T. Chang, Qamar J. Khan, Andrea H. Bild
SESSION PO.MCB10.03 - Non-coding RNAs in Brain, Melanoma, Lung, and Head/Neck
3744 / 2 - A circulating microRNA panel predicts recurrence and survival in early-stage lung adenocarcinoma
9 a.m. – 12:30 p.m.
Mei-Chee Tai, Leonidas E. Bantis, Gargy Parhy, Taketo Kato, Ichidai Tanaka, Chi-Wan Chow, Junya Fujimoto, Carmen Behrens, Tetsunari Hase, Koji Kawaguchi, Johannes F. Fahrmann, Edwin Ostrin, Kohei Yokoi, Toyofumi F. Chen-Yoshikawa, Yoshinori Hasegawa, Samir M. Hanash, Ignacio I. Wistuba, Ayumu Taguchi
SESSION PO.TB04.02 - Regulation of Invasion and Migration
3601 / 7 - Tumor MK2 signaling regulates cell migration and invasion in head and neck squamous cell carcinoma
9 a.m. – 12:30 p.m.
Dakota D. D. Okwuone,Deri Morgan, Hannah M. Smith, Grace Millington, Kiersten L. Berggren, Christopher E. Lominska, Sufi M. Thomas, Gregory N. Gan
SESSION PO.TB06.01 - Pediatric Cancer 3: Genomes and Novel Tumor Models
3551 / 2 - Single-cell characterization of pediatric T-cell acute lymphoblastic leukemia transcriptomes
9 a.m. – 12:30 p.m.
Irina Pushel, Byunggil Yoo, Daniel Louiselle, Margaret Gibson, Midhat S. Farooqi, Keith August
SESSION PO.TB11.01 - Signaling Pathways That Impact the Tumor Microenvironment
3654 / 28 - Olaparib combined with entinostat exerts differential effects on tumor-associated macrophages in tumors compared to ascites in syngeneic HR-proficient murine models of ovarian cancer
9 a.m. – 12:30 p.m.
Vijayalaxmi G. Gupta, Tyler Woodard, Simona Miceska, Bisiyao Fashemi, Sangappa Chadchan, Wendy Zhang, Katherine Roby, Andrew Wilson, Fiona Yull, Marta Crispens, Sumanta Naik, Asya Smimov, Christina Stallings, Dineo Khabele
SESSION PO.CH01.05 - High-throughput Screening, Lead Identification and Optimization, and in Silico Drug Discovery
5334 / 16 - Targeting the KIF15-TPX2 PPI to overcome KIF11 inhibitor resistance in epithelial ovarian cancer
1:30 – 5 p.m.
Benjamin K. Gibbs, Justin T. Douglas, Rebecca J. Wates, Peter R. McDonald, Amy M. Whitaker, Cornelius N. Ndi, Harsh B. Pathak, Laurie A. Harned, Sarah A. Neuenswander, Melinda A. Broward, Bret D. Freudenthal, Anuradha Roy, Frank J. Schoenen, Andrew K. Godwin
SESSION PO.EN01.02 - Endocrine-related Cancers and Nuclear Receptors: Molecular Biology, Biomarkers, and Genomics
5280 / 4 - O-GlcNAcylation of progesterone receptor promotes mammary tumorigenesis
1:30 – 5 p.m.
Harmony Ivanna Saunders, Sean M. Holloran, Gloria Trinca, Chad Slawson, Christy Hagan
SESSION PO.ET01.05 - Targeting Protein Kinases and Phosphatases for Therapy 2
5020 / 12 - IRAK1 is a critical mediator of hyaluronic acid induced stemness
1:30 – 5 p.m.
David Standing, Prasad Dandawate, Jaimie Johnson, Sumedha Gunewardena, Michele T. Pritchard, Harsh Pathak, Dineo Khabele, Katherine Roby, Andrew Godwin, Roy Jensen, Scott Weir, Shrikant Anant
SESSION PO.PR02.02 - Dietary Derivatives and Repurposed and New Drugs for Cancer Prevention
5259 / 13 - Bazedoxifene plus conjugated estrogen improves metabolic health and reduces mammary gland epithelial proliferation in an ovary intact rat model of obesity and breast cancer risk
1:30 – 5 p.m.
Ramsey M. Jenschke, Karen A. Corleto, Carol J. Fabian, Stephen D. Hursting, Bruce F. Kimler, Danilo Landrock, Tara N. Mahmood, Katherine L. Cook, Erin D. Giles
SESSION MS.BCS02.01 - Clinical Applications of Artificial Intelligence and Mathematical Oncology
5693 - Cancer cells subvert fibroblast function to promote a growth factor enriched tumor microenvironment in endocrine therapy resistant ER+ breast cancer
2:37 – 2:52 p.m.
Jason I. Griffiths, Patrick A. Cosgrove, Eric Medina Castaneda, Aritro Nath, Jinfeng Chen, Frederick R. Adler, Jeffrey T. Chang, Qamar J. Khan, Andrea H. Bild
SESSION MS.PR01.01 - Behavioral and Biological Opportunities to Improve Cancer Prevention, Early Detection, and Disparities
2:30 – 4:30 p.m.
Chairperson and Introduction: Andrew K. Godwin
SESSION LE08 - AACR James S. Ewing-Thelma B. Dunn Award for Outstanding Achievement in Pathology in Cancer Research
5:15 – 6 p.m.
Location: Tangerine Ballroom 2, Convention Center
Chairperson: Roy A. JensenApril 19, 2023
SESSION PO.BCS02.02 - Integrative Spatial and Temporal Multi-omics of Cancer
6623 / 28 - Spatial organization of tumor-infiltrating lymphocytes (TILs) is prognostic for survival in triple negative breast cancer (TNBC)
9 a.m. – 12:30 p.m.
Sahil H. Patel, Germán Corredor, Rachel Yoder, Cristian Barrera, Miluska Castillo, Luis Bernabe, Joshua Staley, Shane Stecklein, Satish E. Viswanath, Carlos A. Castaneda, Priyanka Sharma, Anant Madabhushi
SESSION PO.CL07.08 - Immune Monitoring and Responses to Therapy
6675 / 14 - Integration of associations of immune profiles in peripheral blood and tumor microenvironment with bladder cancer outcomes
9 a.m. – 12:30 p.m.
Ji-Qing Chen, Lucas A. Salas, John K. Wiencke, Devin C. Koestler, Annette M. Molinaro, Angeline S. Andrew, John D. Seigne, Margaret R. Karagas, Karl T. Kelsey, Brock C. Christensen
SESSION PO.CL07.10 - Immune Checkpoints
6646 / 18 - Inhibition of HuR/CD147/IL-6 axis enhances anti-PD1 immunotherapy response in cancer
9 a.m. – 12:30 p.m.
Qi Zhang, Lauren Dandreo, Xiaoqing Wu, Liang Xu
SESSION ADT09 - Technical Advances in Liquid Biopsy and Rare Event Detection | Novel technologies for highly efficient isolation and analysis of liquid biopsy markers for cancer disease management applications
10:15 - 11:45 a.m.
Location: Room W414, Convention Center
Presenter: Steven Soper -
Friday, December 9, 2022
New Insights into the Pathogenesis of Thrombotic Thrombocytopenic Purpura: ADAMTS13 Antibody Profiles in TTP
Symposia: Scientific Workshop on Thrombotic Microangiopathies
Program: Scientific Workshops
Time: 2:05 PM-3:10 PM
Location: 293-294 (Ernest N. Morial Convention Center)
Konstantine Halkidis, MD, PhD
A Review of Next-Generation Therapeutics and Contemporary Management of Myelofibrosis
Program: Friday Satellite Symposia
Time: 3:00 PM-6:00 PM
Location: Rhythms Ballroom (Sheraton New Orleans)
Brady L. Stein, MD, MHS and Abdulraheem Yacoub, MD
Saturday, December 10, 2022
151 Predictors and Outcomes of Immune Effector Cell Associated Neurotoxicity Syndrome in Patients Receiving Chimeric Antigen Receptor T-Cell Therapy for Aggressive B-Cell Non-Hodgkin Lymphoma
Session: 627. Aggressive Lymphomas: Clinical and Epidemiological: Treatment of CNS Lymphoma, Neurologic Toxicities, and Relapsed/Refractory DLBCL
Symposia: Aggressive Lymphomas: Clinical and Epidemiological
Program: Oral and Poster Abstracts
Type: Oral
Time: 12 - 1:30 PM
Location: New Orleans Theater C (Ernest N. Morial Convention Center)
Vivek Patel, MD, Shakthi Bhaskar, MD, Stephen J. Schuster, MD, Loretta J. Nastoupil, MD, Miguel-Angel Perales, MD, Roni Shouval, MD, PhD, Joseph P. McGuirk, DO, Richard T. Maziarz, MD, Andy Chen, MD, PhD, Veronika Bachanova, MD, PhD, David L. Porter, MD, Michael R. Bishop, MD, Peter A. Riedell, MD and Olalekan O. Oluwole, MBBS
236 Efficacy and Safety of Add-on Parsaclisib to Ruxolitinib Therapy in Myelofibrosis Patients with Suboptimal Response to Ruxolitinib: Final Results from a Phase 2 Study
Session: 634. Myeloproliferative Syndromes: Clinical and Epidemiological: Latest Data for Combination and Emerging Targeted Therapies in Myelofibrosis
Symposia: Myeloproliferative Syndromes: Clinical and Epidemiological
Program: Oral and Poster Abstracts
Type: Oral
Time: 2:15 PM
Location: 217-219 (Ernest N. Morial Convention Center)
Abdulraheem Yacoub, MD, Uma Borate, MD, Raajit K Rampal, MD, PhD, Haris Ali, MD, Eunice Wang, MD, Aaron T. Gerds, MD, MS, Gabriela S. Hobbs, MD, Marina Kremyanskaya, MD, PhD, Elliott Winton, MD, Casey O’Connell, MD, Swati Goel, MD, Stephen T Oh, MD, PhD, Gary J. Schiller, MD, Albert Assad, MD, Sue Erickson-Viitanen, PhD, Feng Zhou, PhD and Naval Daver, MD
252 Racial and Ethnic Differences in Clinical Outcomes Among Multiple Myeloma Patients Treated with CAR T Therapy
Session: 652. Multiple Myeloma and Plasma Cell Dyscrasias: Clinical and Epidemiological: Relapsed and/or Refractory Myeloma (RRMM)
Symposia: Multiple Myeloma and Plasma Cell Dyscrasias: Clinical and Epidemiological
Program: Oral and Poster Abstracts
Type: Oral
Time: 2:00 PM-3:30 PM
Location: R02-R05 (Ernest N. Morial Convention Center)
Lauren C. Peres, PhD, MPH, Laura B. Oswald, PhD, Christen Dillard, MD, Gabriel De Avila, BS, Taiga Nishihori, MD, Brandon J. Blue, MD, Ciara L. Freeman, MSc, FRCPath, MBBChir, MRCP, Frederick L. Locke, MD, Melissa Alsina, MD, Omar Alexis Castaneda Puglianini, MD, Leyla O. Shune, MD, Douglas W. Sborov, MD, Charlotte B Wagner, PharmD, Danai Dima, MD, Hamza Hashmi, MD, James Davis, PharmD, M. Hakan Kocoglu, MD, Shebli Atrash, MD, Gary Simmons, DO, Nilesh Kalariya, Christopher J. Ferreri, MD, Aishwarya Sannareddy, MBBS, Aimaz Afrough, MD, Peter M. Voorhees, MD, Jack Khouri, MD, Joseph P. McGuirk, DO, Surbhi Sidana, MD, Doris K. Hansen, MD and Krina Patel, MD, MSc
265 Precision-Engineered Cell Therapy Orca-T Demonstrates High Relapse-Free Survival at 1 Year While Reducing Graft-Versus-Host Disease and Toxicity
Session: 732. Allogeneic Transplantation: Disease Response and Comparative Treatment Studies: Clinical Outcome: Real World Studies Based on Database Analyses
Symposia: Allogeneic Transplantation: Disease Response and Comparative Treatment Studies
Program: Oral and Poster Abstracts
Type: Oral
Time: 2:00 PM-3:30 PM
Location: 391 - 392 (Ernest N. Morial Convention Center)
Caspian Oliai, MD, MS, Rasmus T Hoeg, MD, Anna Pavlova, MD, PhD, Arpita Gandhi, MD, Lori Muffly, MD, Rohtesh S. Mehta, MD, Samer A Srour, MD, MS, Edmund K. Waller, MD, PhD, Robert Lowsky, MD, Sagar S. Patel, MD, Bhagirathbhai Dholaria, MBBS, Carlos Bachier, MD, Jeremy M. Pantin, MD, FACP, Amandeep Salhotra, MD, Joseph P. McGuirk, DO, Nathaniel B Fernhoff, PhD, J Scott McClellan, MD, PhD, Mehrdad Abedi, MD, Robert S. Negrin, MD and Everett H Meyer, MD, PhD
362 Final Clinical Outcomes from a Phase 2 Trial of Posoleucel, an Off-the-Shelf, Multivirus-Specific T-Cell Therapy, for the Prevention of Clinically Significant Viral Infections Post-HCT
Session: 704. Cellular Immunotherapies: Early Phase and Investigational Therapies: CAR T in Multiple Myeloma and T-cell Therapies After Allo-HCT
Symposia: Cellular Immunotherapies: Early Phase and Investigational Therapies Program: Oral and Poster Abstracts
Type: Oral
Time: 4:00 PM-5:30 PM
Location: Great Hall AD (Ernest N. Morial Convention Center)
Sanjeet S Dadwal, MD, Jo-Anne H. Young, MD, Michael W. Schuster, MD, Jean A. Yared, MD, Gary Douglas Myers, MD, Michelle Matzko, MD, PhD, Sama Adnan, PhD, Joshua A. Hill, MD and Rajat Bansal, MD
347 Efficacy of Pirtobrutinib, a Highly Selective, Non-Covalent (Reversible) BTK Inhibitor in Richter Transformation: Results from the Phase 1/2 BRUIN Study
Session: 642. Chronic Lymphocytic Leukemia: Clinical and Epidemiological: Targeted Triplet Combinations and Richter’s Transformation
Symposia: Chronic Lymphocytic Leukemia: Clinical and Epidemiological Program: Oral and Poster Abstracts
Type: Oral
Time: 4:00 PM-5:30 PM
Location: R06-R09 (Ernest N. Morial Convention Center)
William G. Wierda, MD, PhD, David John Lewis, MBChB, PhD, Paolo Ghia, MD, PhD, Nirav N. Shah, MD, Catherine C. Coombs, MD, Chan Yoon Y. Cheah, MD, Nicole Lamanna, MD, Joanna M. Rhodes, MD, MSCE, Marc Hoffmann, MD, Shuo Ma, MD, Toby A. Eyre, MBChB, DipMedEd, MRCP, FRCPath, MD, Talha Munir, MBBS, MRCP, FRCPath, PhD, Manish R. Patel, MD, Alvaro J. Alencar, MD, Constantine S. Tam, MD, MBBS, John F. Seymour, MBBS, PhD, FRACP, Wojciech Jurczak, Ewa Lech-Marańda, MD, PhD, Lindsey E. Roeker, MD, Philip A. Thompson, MBBS, Paolo B. Abada, MD, PhD, Chunxiao Wang, PhD, Binoj Nair, PhD, Hui Liu, MD, PhD, Donald E. Tsai, MD, PhD and Anthony R. Mato, MD, MSCE
1112 The Potential Role of ANKRD36 in Immune Thrombotic Thrombocytopenic Purpura
Session: 301. Vasculature, Endothelium, Thrombosis and Platelets: Basic and Translational: Poster I
Symposia: Vasculature, Endothelium, Thrombosis and Platelets: Basic and Translational
Program: Oral and Poster Abstracts
Time: 5:30 PM-7:30 PM
Location: Hall D (Ernest N. Morial Convention Center)
Aria Bales, B.A., Liang Zheng, Ph.D., Antonia Bignotti, B.A., Mark Cunningham, M.D. and X. Long Zheng, MD, PhD
1412 A Pilot Study of Azacitidine as Epigenetic Priming for Chemotherapy in Infants Less Than 1 Year of Age with KMT2A-Rearranged Acute Lymphoblastic Leukemia (ALL); Results from the Children’s Oncology Group (COG) Trial AALL15P1
Session: 614. Acute Lymphoblastic Leukemias: Therapies, Excluding Transplantation and Cellular Immunotherapies: Poster I
Symposia: Acute Lymphoblastic Leukemias: Therapies, Excluding Transplantation and Cellular Immunotherapies
Program: Oral and Poster Abstracts
Time: 5:30 PM-7:30 PM
Location: Hall D (Ernest N. Morial Convention Center)
Erin Guest, MD, John Kairalla, PhD, Meenakshi Devidas, PhD, MBA, Emily Hibbitts, MS, Andrew J. Carroll, PhD, Nyla A. Heerema, PhD, Holly Kubaney, MSN, RN, PPCNP-BC, CPHON, Amanda August, PharmD, Melinda Pauly, MD, Daniel Wechsler, MD, PhD, Rodney R. Miles, MD, PhD, Joel M. Reid, PhD, Cynthia Kihei, BSN, Lia Gore, Elizabeth A. Raetz, MD, Stephen P. Hunger, MD, Mignon L. Loh, MD and Patrick A. Brown, MD
1423 Lower-Intensity CPX-351 + Venetoclax for Patients with Newly Diagnosed Acute Myeloid Leukemia Who Are Unfit for Intensive Chemotherapy: Post Hoc Analysis by Disease Risk Subgroups
Session: 615. Acute Myeloid Leukemias: Commercially Available Therapies, Excluding Transplantation and Cellular Immunotherapies: Poster I
Symposia: Acute Myeloid Leukemias: Commercially Available Therapies, Excluding Transplantation and Cellular Immunotherapies
Program: Oral and Poster Abstracts
Time: 5:30 PM-7:30 PM
Location: Hall D (Ernest N. Morial Convention Center)
Tara L. Lin, MD, Praneeth Baratam, Robert K. Stuart, Roland B. Walter, MD, PhD, MS, Eric S. Winer, MD, Stefan Faderl, Vijayalakshmi Chandrasekaran, Divya Chakravarthy, Ronald S. Cheung and Vinod A. Pullarkat, MD
1436 V-FAST Master Trial: Subgroup Analysis of Outcomes with CPX-351 Plus Midostaurin in Adults with Newly Diagnosed Acute Myeloid Leukemia by FLT3 Mutation Type
Session: 615. Acute Myeloid Leukemias: Commercially Available Therapies, Excluding Transplantation and Cellular Immunotherapies: Poster I
Symposia: Acute Myeloid Leukemias: Commercially Available Therapies, Excluding Transplantation and Cellular Immunotherapies
Program: Oral and Poster Abstracts
Time: 5:30 PM-7:30 PM
Location: Hall D (Ernest N. Morial Convention Center)
James McCloskey, MD, Vinod A. Pullarkat, MD, Gabriel N. Mannis, MD, Tara L. Lin, MD, Stephen A Strickland, MD, MSC, Amir T. Fathi, MD, Stefan Faderl, Divya Chakravarthy, Yana Lutska, Vijayalakshmi Chandrasekaran, Ronald S. Cheung and Mark J. Levis, MD
1472 Clinical and Functional Implications of MYC Variants As a New Class of Pathogenic Variants in AML
Session: 617. Acute Myeloid Leukemias: Biomarkers, Molecular Markers and Minimal Residual Disease in Diagnosis and Prognosis: Poster I
Symposia: Acute Myeloid Leukemias: Biomarkers, Molecular Markers and Minimal Residual Disease in Diagnosis and Prognosis
Program: Oral and Poster Abstracts
Time: 5:30 PM-7:30 PM
Location: Hall D (Ernest N. Morial Convention Center)
Danielle C. Kirkey, MD, Xiaoying Wu, PhD, Rhonda E. Ries, MA, Tiffany A. Hylkema, BS, Yanling Liu, PhD, Pandurang Kolekar, PhD, Quang Tran, PhD, Alan S. Gamis, MD, MPH, Richard Aplenc, MD, PhD, Anders E. Kolb, MD, Todd A. Alonzo, PhD, Katherine Tarlock, MD, Robert Eisenman, PhD and Soheil Meshinchi, M.D., Ph.D.
1496 Prognosis of NF1 Mutations in Acute Myeloid Leukemia
Session: 617. Acute Myeloid Leukemias: Biomarkers, Molecular Markers and Minimal Residual Disease in Diagnosis and Prognosis: Poster I
Symposia: Acute Myeloid Leukemias: Biomarkers, Molecular Markers and Minimal Residual Disease in Diagnosis and Prognosis
Program: Oral and Poster Abstracts
Time: 5:30 PM-7:30 PM
Location: Hall D (Ernest N. Morial Convention Center)
Joshua Tatarian, Stephen Hyter, PhD, Andrew K. Godwin, PhD, Daniel Farrell, MD, Tara L. Lin, MD and Haitham Abdelhakim, MD
1711 Safety and Efficacy of Fedratinib in Patients with Primary (P), Post-Polycythemia Vera (Post-PV), and Post-Essential Thrombocythemia (Post-ET) Myelofibrosis (MF) Previously Treated with Ruxolitinib: Primary Analysis of the FREEDOM Trial
Session: 634. Myeloproliferative Syndromes: Clinical and Epidemiological: Poster I
Symposia: Myeloproliferative Syndromes: Clinical and Epidemiological
Program: Oral and Poster Abstracts
Time: 5:30 PM-7:30 PM
Location: Hall D (Ernest N. Morial Convention Center)
Vikas Gupta, MD, FRCP, FRCPath, Abdulraheem Yacoub, MD, Srdan Verstovsek, MD, PhD, Ruben Mesa, MD, FACP, Claire N. Harrison, DM, Alessandro M. Vannucchi, MD, Jean-Jacques Kiladjian, H. Joachim Deeg, MD, Salman Fazal, MD, Lynda Foltz, Ryan J. Mattison, MD, Carole B. Miller, MD, Vinod Parameswaran, MD, Patricia Martin-Regueira, MD, Christopher Hernandez, MSc, Jia Wang and Moshe Talpaz, MD
1797 Safety and Tolerability of Pirtobrutinib Monotherapy in Patients with B-Cell Malignancies Who Were Previously Intolerant to a Covalent BTK Inhibitor: Results from the Phase 1/2 BRUIN Study
Session: 642. Chronic Lymphocytic Leukemia: Clinical and Epidemiological: Poster I
Symposia: Chronic Lymphocytic Leukemia: Clinical and Epidemiological
Program: Oral and Poster Abstracts
Time: 5:30 PM-7:30 PM
Location: Hall D (Ernest N. Morial Convention Center)
Nirav N. Shah, MD, Michael L. Wang, MD, Jennifer R. Brown, MD, PhD, Krish Patel, MD, Jennifer A. Woyach, MD, William G. Wierda, MD, PhD, Chaitra S. Ujjani, MD, Toby A. Eyre, MBChB, DipMedEd, MRCP, FRCPath, MD, Pier Luigi Zinzani, MD, PhD, Alvaro J. Alencar, MD, Thomas Gastinne, MD, Paolo Ghia, MD, PhD, Nicole Lamanna, MD, Marc Hoffmann, MD, Manish R. Patel, MD, Ian W. Flinn, MD PhD, James N. Gerson, MD, Shuo Ma, MD, Catherine C. Coombs, MD, Chan Yoon Y. Cheah, MD, Ewa Lech-Marańda, MD, PhD, Bita Fakhri, MD, MPH, Won-Seog Kim, Minal A. Barve, MD, Jonathon B. Cohen, MD, MS, Wojciech Jurczak, MD, PhD, Talha Munir, MBBS, MRCP, FRCPath, PhD, Meghan C. Thompson, MD, Lindsey E. Roeker, MD, Katherine Bao, PhD, Nicholas A. Cangemi, BS, Jennifer F. Kherani, MD, Richard A. Walgren, MD, PhD, Hongmei Han, MS, Amy S. Ruppert, PhD and Anthony R. Mato, MD, MSCE
1862 Outcomes of Patients Who Are BCMA (B-cell maturation Antigen) Directed Therapy (BDT) Exposed Vs BCMA Naïve in Penta-Relapsed Refractory Multiple Myeloma (RRMM)
Session: 652. Multiple Myeloma and Plasma Cell Dyscrasias: Clinical and Epidemiological: Poster I
Symposia: Multiple Myeloma and Plasma Cell Dyscrasias: Clinical and Epidemiological
Program: Oral and Poster Abstracts
Time: 5:30 PM-7:30 PM
Location: Hall D (Ernest N. Morial Convention Center)
Aytaj Mammadzadeh, Fulei Peng, MD, Shebli Atrash, MD, Hamza Hashmi, MD, Meera Mohan, MD, Omar Alkharabsheh, MBBS, Aimaz Afrough, MD, Wei Cui, MD, Zahra Mahmoudjafari, PhD and Al-Ola Abdallah, MD
1918 Iberdomide (IBER) in Combination with Dexamethasone (DEX) in Relapsed/Refractory Multiple Myeloma (RRMM): Results from the Anti-B-Cell Maturation Antigen (BCMA)-Exposed Cohort of the CC-220-MM-001 Trial
Session: 653. Myeloma and Plasma Cell Dyscrasias: Prospective Therapeutic Trials: Poster I
Symposia: Myeloma and Plasma Cell Dyscrasias: Prospective Therapeutic Trials
Program: Oral and Poster Abstracts
Time: 5:30 PM-7:30 PM
Location: Hall D (Ernest N. Morial Convention Center)
Sagar Lonial, MD, Al-Ola Abdallah, MD, Faiz Anwer, MD, Ashraf Z. Badros, MD, Manisha Bhutani, MD, Abdullah Khan, MBBS, MSc, Brea Lipe, MD, Albert Oriol, Darrell White, MD, Michael Amatangelo, PhD, Kexin Jin, Mark Masin, Vi Nguyen, Alpesh Amin, Paulo Maciag, MD PhD and Niels WCJ Van De Donk, MD
2000 Interim Phase I Clinical Data of FT819-101, a Study of the First-Ever, Off-the-Shelf, iPSC‑Derived TCR‑Less CD19 CAR T‑Cell Therapy for Patients with Relapsed/Refractory B‑Cell Malignancies
Session: 704. Cellular Immunotherapies: Early Phase and Investigational Therapies: Poster I
Symposia: Cellular Immunotherapies: Early Phase and Investigational Therapies
Program: Oral and Poster Abstracts
Time: 5:30 PM-7:30 PM
Location: Hall D (Ernest N. Morial Convention Center)
Amitkumar Mehta, MD, Umar Farooq, MD, Andy Chen, MD, PhD, Joseph P. McGuirk, DO, Thomas Ly, PhD, Lilly Wong, PhD, Sarah Cooley, MD, Bahram Valamehr, Rebecca Elstrom, MD, Yu-Waye Chu, MD and Jae H Park, MD
2027 Factors Associated with Refractoriness or Early Progression after Idecabtagene Vicleucel (Ide-cel) in Patients with Relapsed/Refractory Multiple Myeloma (RRMM): U.S. Myeloma CAR T Consortium Real World Experience
Session: 705. Cellular Immunotherapies: Late Phase and Commercially Available Therapies: Poster I
Symposia: Cellular Immunotherapies: Late Phase and Commercially Available Therapies
Program: Oral and Poster Abstracts
Time: 5:30 PM-7:30 PM
Location: Hall D (Ernest N. Morial Convention Center)
Hamza Hashmi, MD, Doris K. Hansen, MD, Lauren C. Peres, PhD, MPH, Omar Alexis Castaneda Puglianini, MD, Ciara L. Freeman, MSc, FRCPath, MBBChir, MRCP, Gabriel De Avila, BS, Surbhi Sidana, MD, Leyla O. Shune, MD, Douglas W. Sborov, MD, James Davis, PharmD, Charlotte B Wagner, PharmD, M. Hakan Kocoglu, MD, Shebli Atrash, MD10, Peter M. Voorhees, MD, Gary Simmons, DO, Christopher J. Ferreri, MD, Nilesh Kalariya, Aishwarya Sannareddy, MBBS, Danai Dima, MD, Jack Khouri, MD, Joseph P. McGuirk, DO, Frederick L. Locke, MD, Rachid C. Baz, MD, Krina Patel, MD, MSc and Melissa Alsina, MD
2033 Peripheral Blast Count at Apheresis Acts Independent of Disease Burden as a Risk Factor for Survival Following Tisagenlecleucel in Children and Young Adults
Session: 705. Cellular Immunotherapies: Late Phase and Commercially Available Therapies: Poster I
Symposia: Cellular Immunotherapies: Late Phase and Commercially Available Therapies
Program: Oral and Poster Abstracts
Time: 5:30 PM-7:30 PM
Location: Hall D (Ernest N. Morial Convention Center)
Vanessa A Fabrizio, MD, Kristen Miller, MS, Christina Baggott, RN, PhD, Snehit Prabhu, PhD, Holly Pacenta, MD, Christine L. Phillips, MD, Jenna Rossoff, MD, Heather E Stefanski, MD, Julie Talano, MD, Amy Moskop, MD, MS, Susanne H.C. Baumeister, MD, Gary Douglas Myers, MD, Nicole Karras, MD, Patrick A. Brown, MD, Muna Qayed, MD, MSc, Michelle L. Hermiston, MD, PhD, Prakash Satwani, MD, Christa Krupski, DO, MPH, Rachel Wilcox, Vasant Chinnabhandar, MD, MBBS, Kevin J. Curran, MD, Crystal L. Mackall, MD, Theodore W. Laetsch, MD, Amy K. Keating, MD, Michael R Verneris, MD and Liora M. Schultz, MD
2211 Time to Event Surrogate Endpoints in Multiple Myeloma Randomized Trials from 2005-2019: A Surrogacy Analysis
Session: 902. Health Services and Quality—Lymphoid Malignancies: Poster I
Symposia: Health Services and Quality—Lymphoid Malignancies
Program: Oral and Poster Abstracts
Time: 5:30 PM-7:30 PM
Location: Hall D (Ernest N. Morial Convention Center)
Tommy Etekal, Kelly Koehn, MD, Douglas W. Sborov, MD, Brian McClune, DO, Vinay Prasad, Alyson Haslam, Katherine Berger, Christopher Booth, MD, Samer Al Hadidi, MD, MSc, Al-Ola Abdallah, MD, Aaron M Goodman and Ghulam Rehman Mohyuddin, MD
Sunday, December 11, 2022
422 Distinct Latent Trajectory Phenotypes of Left Ventricular Function Associated with Differential Survival Among Children Treated for Acute Myeloid Leukemia: A Report from the Children’s Oncology Group
Session: 613. Acute Myeloid Leukemias: Clinical and Epidemiological: Clinical Care and Observations in Acute Myeloid Leukemia
Symposia: Acute Myeloid Leukemias: Clinical and Epidemiological
Program: Oral and Poster Abstracts
Time: 9:30 AM-11:00 AM
Location: La Nouvelle Orlens Ballroom AB (Ernest N. Morial Convention Center)
Kelly D. Getz, Robert B. Gerbing, MA, Todd A. Alonzo, PhD, Yimei Li, PhD, Kasey J Leger, MD, MSc, Jessica A. Pollard, MD, Dava Szalda, MD MSHP, Lillian Sung, MD, PhD, Todd M. Cooper, DO, Edward A. Kolb, MD, Alan S. Gamis, MD, MPH, Bonnie Ky, MD and Richard Aplenc, MD, PhD
554 Poor Survival Outcomes of Checkpoint Inhibitors for B-Cell Lymphomas Relapsing after or Refractory to CAR T-Cell Therapy: A Real-World Cohort from 15 U.S. Academic Institutions
Session: 627. Aggressive Lymphomas: Clinical and Epidemiological: Real World Evidence for Management of CNS Lymphoma and Post CAR T-cell relapse for aggressive B-cell NHL
Symposia: Aggressive Lymphomas: Clinical and Epidemiological
Program: Oral and Poster Abstracts
Time: 12 PM-1:30 PM
Location: R02-R05 (Ernest N. Morial Convention Center)
Ajay Major, MD, MBA, Jovian Yu, MD, MS, Navika D. Shukla, MD, Rachel Treitman, BS, Manali K. Kamdar, MD, Bradley M. Haverkos, MD, MS, MPH, James Godfrey, MD, Melissa A. Babcook, MD, PhD, Timothy J. Voorhees, MD, MSc, Sophie G Carlson, MD, Daria Gaut, MD, Caspian Oliai, MD, MS, Jason T. Romancik, MD, Allison Winter, MD, Brian T. Hill, MD, PhD, Radhika Bansal, MBBS, Jose C. Villasboas, MD, Imran A. Nizamuddin, MD, Reem Karmali, MD, MSc, Lindsey A. Fitzgerald, MD, Deborah M. Stephens, DO, Priyanka A. Pophali, MD, Asaad Trabolsi, MD, Jonathan H. Schatz, MD, Marie Hu, MD, Veronika Bachanova, MD, PhD, Michael J Slade, MD, MS, Nathan Singh, MD, Nausheen Ahmed, MBBS, Joseph P. McGuirk, DO, Michael R. Bishop, MD, Peter A. Riedell, MD and Justin Kline, MD
608 Long-Term Clinical Outcomes and Correlative Efficacy Analyses in Patients (Pts) with Relapsed/Refractory Follicular Lymphoma (r/r FL) Treated with Tisagenlecleucel in the Elara Trial Clinically Relevant Abstract
Session: 623. Mantle Cell, Follicular, and Other Indolent B Cell Lymphomas: Clinical and Epidemiological IV
Symposia: Mantle Cell, Follicular, and Other Indolent B Cell Lymphomas: Clinical and Epidemiological
Program: Oral and Poster Abstracts
Time: 4:30 PM-6:00 PM
Location: 278-282 (Ernest N. Morial Convention Center)
Martin Dreyling, MD, Michael Dickinson, MD, Joaquin Martinez Lopez, Arne Kolstad, MD, PhD, Jason P Butler, MBBS, MMedSc, Monalisa Ghosh, MD, Leslie L. Popplewell, MD, FACP, MPH, Julio Chavez, Emmanuel Bachy, MD, PhD, Koji Kato, MD, PhD, Hideo Harigae, MD, PhD, Marie Jose Kersten, MD, PhD, Charalambos Andreadis, MD, MSCE, Peter A. Riedell, MD, Phoebe Joy Ho, MBBS(Syd) DPhil(Oxon) FRACP FRCPA FFSc(RCPA), Jose A. Perez-Simon, MD, PhD, Andy Chen, MD, PhD, Loretta J. Nastoupil, MD, Bastian von Tresckow, MD, Andrés J M Ferreri, MD, Takanori Teshima, M.D., Ph.D., Piers E.M. Patten, Joseph P. McGuirk, DO, Andreas Petzer, MD, Fritz Offner, MD, PhD, Andreas Viardot, MD, Pier Luigi Zinzani, MD, PhD, Ram Malladi, MD, Ines Paule, Aiesha Zia, Rakesh Awasthi, PhD, Xia Han, MS, Davide Germano, Darragh O'Donovan, PhD, Roberto Ramos, MD, Aisha Masood, MD, Catherine Thieblemont, MD, PhD, Nathan H. Fowler, MD and Stephen J. Schuster, MD
461 ASTX727-03: Phase 1 Study Evaluating Oral Decitabine/Cedazuridine (ASTX727) Low-Dose (LD) in Lower-Risk Myelodysplastic Syndromes (LR-MDS) Patients
Session: 637. Myelodysplastic Syndromes – Clinical and Epidemiological II
Symposia: Myelodysplastic Syndromes – Clinical and Epidemiological
Program: Oral and Poster Abstracts
Time: 4:30 PM-6:00 PM
Location: R06-R09 (Ernest N. Morial Convention Center)
Guillermo Garcia-Manero, MD, Kimo Bachiashvili, MD, Harshad Amin, MD, Elie Traer, MD, PhD, Daniel A. Pollyea, MD, David A. Sallman, MD, Aref Al-Kali, MD, Larry D. Cripe, MD, Jesus G Berdeja, MD, Elizabeth A. Griffiths, MD, Sanjay R Mohan, MD, MSCI, Yuri Sano, MD, Aram Oganesian, PhD, Harold N. Keer, MD, PhD and Abdulraheem Yacoub, MD
657 Population Pharmacokinetic Model Identifies an Optimal Fludarabine Exposure for Improved Outcomes after CD19-Directed CAR T Cell Therapy for Aggressive B-NHL: Analysis from the Cell Therapy Consortium
Session: 705. Cellular Immunotherapies: Results from CD19-Directed CAR T in treating Aggressive B-cell Lymphomas
Symposia: Cellular Immunotherapies: Late Phase and Commercially Available Therapies
Program: Oral and Poster Abstracts
Time: 4:30 PM-6:00 PM
Location: Hall E (Ernest N. Morial Convention Center)
Michael Scordo, MD, Jessica R. Flynn, MS, Sean M. Devlin, PhD, Mithat Gonen, PhD, Allison Parascondola, BA, Ana Alarcon Tomas, MD, Roni Shouval, MD, PhD, Jamie Brower, MS, David L. Porter, MD, Stephen J. Schuster, MD, Veronika Bachanova, MD, PhD, Joseph E. Maakaron, MD, Richard T. Maziarz, MD, Loretta J. Nastoupil, MD, Joseph P. McGuirk, DO, Olalekan O. Oluwole, MBBS, Andrew Ip, MD, MSc, Lori A. Leslie, MD, Michael R. Bishop, MD, Peter A. Riedell, MD and Miguel-Angel Perales, MD
659 Outcomes of Subsequent Anti-Lymphoma Therapies in Patients (Pts) with Large B-Cell Lymphoma (LBCL) Treated with Axicabtagene Ciloleucel (Axi-Cel) or Standard of Care (SOC) in the Second-line (2L) ZUMA-7 Study
Session: 705. Cellular Immunotherapies: Results from CD19-Directed CAR T in treating Aggressive B-cell Lymphomas
Symposia: Cellular Immunotherapies: Late Phase and Commercially Available Therapies
Program: Oral and Poster Abstracts
Time: 4:30 PM-6:00 PM
Location: Hall E (Ernest N. Morial Convention Center)
Armin Ghobadi, MD, Javier Munoz, MD, MS, MBA, Jason Westin, MD, Frederick L. Locke, MD, David B. Miklos, MD, PhD, Aaron P. Rapoport, MD, Miguel-Angel Perales, MD, Patrick M. Reagan, MD, Joseph P. McGuirk, DO, Caron A. Jacobson, MD, Marie José Kersten, MD, PhD, Irit Avivi, MD, Andrew Peng, MS, Marco Schupp, MD13*, Christina To, MD and Olalekan O. Oluwole, MBBS
2433 The Mechanism of Antibody-Mediated Inhibition of ADAMTS13 in Immune Thrombotic Thrombocytopenic Purpura
Session: 301. Vasculature, Endothelium, Thrombosis and Platelets: Basic and Translational: Poster II
Symposia: Vasculature, Endothelium, Thrombosis and Platelets: Basic and Translational
Program: Oral and Poster Abstracts
Time: 6:00 PM-8:00 PM
Location: Hall D (Ernest N. Morial Convention Center)
Chan Meng, MD, Konstantine Halkidis, MD, PhD, Szumam Liu, Ph.D., Don L. Siegel, M.D., Ph.D. and X. Long Zheng, MD, PhD
2457 Coagulation Factor VIII Enhances the Cleavage of Von Willebrand Factor By ADAMTS13 In Vivo
Session: 321. Coagulation and Fibrinolysis: Basic and Translational: Poster II
Symposia: Coagulation and Fibrinolysis: Basic and Translational
Program: Oral and Poster Abstracts
Time: 6:00 PM-8:00 PM
Location: Hall D (Ernest N. Morial Convention Center)
Wenjing Cao, Aria Bales, B.A., Antonia Bignotti, B.A., Noritaka Yada, Liang Zheng, PhD, Lindsey George, M.D., Denise E. Sabatino, PhD, Marie Scully, MD, Rodney M. Camire, Ph.D. and X. Long Zheng, MD, PhD
2690 Desensitization to Pegaspargase in Children with Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma Is Safe and Does Not Require Intensive Care – a Single Center Experience
Session: 612. Acute Lymphoblastic Leukemias: Clinical and Epidemiological: Poster II
Symposia: Acute Lymphoblastic Leukemias: Clinical and Epidemiological
Program: Oral and Poster Abstracts
Time: 6:00 PM-8:00 PM
Location: Hall D (Ernest N. Morial Convention Center)
Keith J August, MD, MS, Tristan Flatt, DO, Joy M. Fulbright, MD, Alan S. Gamis, MD, MPH, Julia A. Hays, MD, Maxine J Hetherington, MD, Karen Lewing, MD, CPC, Amanda August, PharmD and Erin Guest, MD
2801 Pathogenic TP53 mutations Are Associated with a Poor Prognosis in De Novo AML
Session: 617. Acute Myeloid Leukemias: Biomarkers, Molecular Markers and Minimal Residual Disease in Diagnosis and Prognosis: Poster II
Symposia: Acute Myeloid Leukemias: Biomarkers, Molecular Markers and Minimal Residual Disease in Diagnosis and Prognosis
Program: Oral and Poster Abstracts
Time: 6:00 PM-8:00 PM
Location: Hall D (Ernest N. Morial Convention Center)
Adam J. Lamble, MD, Rhonda E. Ries, MA, Alice Dang, Ph.D., Todd A. Alonzo, PhD, Karen Chisholm, Pandurang Kolekar, PhD, Yanling Liu, PhD, Quang Tran, PhD, Todd M. Cooper, DO, Richard Aplenc, MD, PhD, Alan S. Gamis, MD, MPH, Edward A. Kolb, MD10, Xiaotu Ma, PhD and Soheil Meshinchi, M.D., Ph.D.
2819 Single-Cell Transcriptomics Reveals Similarity of Aggressive Infant Acute Lymphoblastic Leukemia Cells to Early Hematopoietic Progenitors
Session: 618. Acute Lymphoblastic Leukemias: Biomarkers, Molecular Markers and Minimal Residual Disease in Diagnosis and Prognosis: Poster II
Symposia: Acute Lymphoblastic Leukemias: Biomarkers, Molecular Markers and Minimal Residual Disease in Diagnosis and Prognosis
Program: Oral and Poster Abstracts
Time: 6:00 PM-8:00 PM
Location: Hall D (Ernest N. Morial Convention Center)
Irina Pushel, PhD, Midhat S. Farooqi, MD, PhD, Byunggil Yoo, MS, Kai Tan, PhD, Kathrin M. Bernt, MD and Erin Guest, MD
2842 Correlation of Minimal Residual Disease (MRD) at the End of Induction (EOI) and Event Free Survival (EFS) in T-Cell Lymphoblastic Lymphoma (T-LL), a Report from the Children’s Oncology Group (COG) Trial AALL1231
Session: 621. Lymphomas: Translational—Molecular and Genetic: Poster II
Symposia: Lymphomas: Translational—Molecular and Genetic
Program: Oral and Poster Abstracts
Time: 6:00 PM-8:00 PM
Location: Hall D (Ernest N. Morial Convention Center)
Robert J. Hayashi, Michelle L. Hermiston, MD, PhD, David T. Teachey, MD, Meenakshi Devidas, PhD, MBA, Brent L. Wood, MD PhD, Zhiguo Chen, MS, Robert D Annett, Ph.D., Barbara L Asselin, MD, Keith J August, MD, MS, Steve Y Cho, MD, Kimberly P. Dunsmore, MD, Jason L. Freedman, MD, Paul J. Galardy, MD, Paul Harker-Murray, MD, PhD, Terzah M. Horton, MD, PhD, Alok I Jaju, MD, Allison Lam, BCPS, Yoav H. Messinger, MD, Rodney R. Miles, MD, PhD, Maki Okada, RN, Samir I Patel, MD, Eric S Schafer, MD, Tal Schechter-Finkelstein, MD, Kristin A. Shimano, MD, Neelam Singh, PhD, Amii C. Steele, PhD, Maria Luisa Sulis, MD, Sarah L Vargas, PhD, Stuart S. Winter, MD, Charlotte Wood, CCRP, Patrick A Zweidler-McKay, MD, PhD, Mignon L. Loh, MD, Stephen P. Hunger, MD, Elizabeth A. Raetz, MD, Catherine M Bollard, MD and Carl Allen, MD
3187 Daratumumab,Pomalidomide and Dexamethasone (DPd) Versus Daratumumab, Velcade and Dexamethasone (DVd) in Previously Treated Daratumumab Naïve Relapsed Refractory Multiple Myeloma Patients
Session: 652. Multiple Myeloma and Plasma Cell Dyscrasias: Clinical and Epidemiological: Poster II
Symposia: Multiple Myeloma and Plasma Cell Dyscrasias: Clinical and Epidemiological
Program: Oral and Poster Abstracts
Time: 6:00 PM-8:00 PM
Location: Hall D (Ernest N. Morial Convention Center)
Evguenia Ouchveridze, MD, Chandandeep Singh, MD, Shebli Atrash, MD, Barry Paul, MD, MS, Meera Mohan, MD, Omar Alkharabsheh, MBBS, Aimaz Afrough, MD, Wei Cui, MD, Zahra Mahmoudjafari, PhD, Al-Ola Abdallah, MD and Hamza Hashmi, MD
3240 Updated Interim Results from a Phase 1 Study of HPN217, a Half-Life Extended Tri-Specific T Cell Activating Construct (TriTAC®) Targeting B Cell Maturation Antigen (BCMA) for Relapsed/Refractory Multiple Myeloma (RRMM)
Session: 653. Myeloma and Plasma Cell Dyscrasias: Prospective Therapeutic Trials: Poster II
Symposia: Myeloma and Plasma Cell Dyscrasias: Prospective Therapeutic Trials
Program: Oral and Poster Abstracts
Time: 6:00 PM-8:00 PM
Location: Hall D (Ernest N. Morial Convention Center)
Al-Ola Abdallah, MD, Andrew J Cowan, MD, Xavier Leleu, MD, PhD, Cyrille Touzeau, Brea Lipe, MD, Eva Medvedova, MD, Caitlin Costello, MD, Jens Hillengass, MD, PhD, P. Leif Bergsagel, MD, Raya Mawad, MD, Henning Schade, MD, Daniel Morillo Giles, Albert Oriol, MD, Yifah Yaron, Patrick P Ng and Sumit Madan, MD
3246 Single-Agent Belantamab Mafodotin in Patients with Relapsed or Refractory Multiple Myeloma: Final Analysis of the DREAMM-2 Trial
Session: 653. Myeloma and Plasma Cell Dyscrasias: Prospective Therapeutic Trials: Poster II
Symposia: Myeloma and Plasma Cell Dyscrasias: Prospective Therapeutic Trials
Program: Oral and Poster Abstracts
Time: 6:00 PM-8:00 PM
Location: Hall D (Ernest N. Morial Convention Center)
Ajay K. Nooka, MD, MPH, FACP, Adam Cohen, MD, Hans C. Lee, MD, Ashraf Z. Badros, MD, Attaya Suvannasankha, MD, Natalie Callander, MD, Al-Ola Abdallah, MD, Suzanne Trudel, MD, Ajai Chari, MD, Edward Libby, MD, Maria Chaudhry, MD, Malin Hultcrantz, MD, PhD, Martin Kortuem, Paul G. Richardson, MD, Rakesh Popat, Douglas W. Sborov, MD, Shawn Hakim, PhD, Eric Lewis, MD, Bharat Bhushan, MSc, Boris Gorsh, PharmD, Ira Gupta, MD, Joanna Opalinska, MD and Sagar Lonial, MD
3323 Relapse Prophylaxis Post-Haploidentical Bone Marrow Transplantation and Cyclophosphamide (Haplo/Cy) By Infusion of Donor-Derived Expanded/Activated Gd T Cells: A Phase I Trial
Session: 704. Cellular Immunotherapies: Early Phase and Investigational Therapies: Poster II
Symposia: Cellular Immunotherapies: Early Phase and Investigational Therapies
Program: Oral and Poster Abstracts
Time: 6:00 PM-8:00 PM
Location: Hall D (Ernest N. Morial Convention Center)
Joseph P. McGuirk, DO, Sunil H Abhyankar, MD, Trishna Goswami, MD, Rupal Soder, PhD, Mariska ter Haak, Tyce Bruns, Samantha Langford Youngblood, BS and Lawrence S. Lamb Jr., PhD
3335 A Phase 2/3, Randomized, Double Blind, Placebo-Controlled, Multicenter Study of NKTR-255 Vs Placebo Following CD-19 Directed CAR-T Therapy in Patients with Relapsed/Refractory Large B-Cell Lymphoma
Session: 704. Cellular Immunotherapies: Early Phase and Investigational Therapies: Poster II
Symposia: Cellular Immunotherapies: Early Phase and Investigational Therapies
Program: Oral and Poster Abstracts
Time: 6:00 PM-8:00 PM
Location: Hall D (Ernest N. Morial Convention Center)
Miguel-Angel Perales, MD, Sairah Ahmed, MD, Saurabh Dahiya, MD, Peter A. Riedell, MD, Joseph P. McGuirk, DO, Olalekan O. Oluwole, MBBS, Sohail A. Chaudhry, MD, Zachary Lee, PharmD, Stanley Dai, Neha Dixit, PhD, Christie Fanton, PhD, Mario Q. Marcondes, MD, PhD, Jonathan Zalevsky, PhD, Mary A. Tagliaferri, MD and Cameron J. Turtle, MBBS, PhD
3579 Patient-Reported Outcomes in Long-Term Survivors of Autologous Hematopoietic Cell Transplantation for Hodgkin and Non-Hodgkin Lymphoma: Secondary Analysis from Two Multi-Center Randomized Controlled Trials of Hematopoietic Cell Transplant Survivorship Interventions
Session: 905. Outcomes Research—Lymphoid Malignancies: Poster II
Symposia: Outcomes Research—Lymphoid Malignancies
Program: Oral and Poster Abstracts
Time: 6:00 PM-8:00 PM
Location: Hall D (Ernest N. Morial Convention Center)
Agrima Mian, MBBS, MD, Wei Wei, MSc, Rajshekhar Chakraborty, MBBS, Jean C. Yi, PhD, Jaime M. Preussler, MS, Brian T. Hill, MD, PhD, Jan Cerny, MD, PhD, Abhinav Deol, MD, Theresa E. Hahn, PhD, Shahrukh K. Hashmi, MD, MPH, Samantha Jaglowski, MD, MPH, Heather S. L. Jim, PhD, Nandita Khera, MD, MPH, Alison W. Loren, MD, Joseph P. McGuirk, DO, Bipin N. Savani, MD, Patrick Stiff, MD, Joseph P. Uberti, M.D., Ph.D., Victoria Whalen, B.S., John R. Wingard, MD, Jana Reynolds, MD, Shernan G Holtan, MD, William A. Wood, MD, MPH, K. Scott Baker, MD, MS, Karen L. Syrjala, PhD, Betty K. Hamilton, MD and Navneet S. Majhail, MD.
3605 Hematological and Non-Hematological Toxicities in Patients with Relapsed/Refractory Multiple Myeloma (RRMM) Who Responded to Daratumumab, Pomalidomide, and Dexamethasone (DPd)
Session: 905. Outcomes Research—Lymphoid Malignancies: Poster II
Symposia: Outcomes Research—Lymphoid Malignancies
Program: Oral and Poster Abstracts
Time: 6:00 PM-8:00 PM
Location: Hall D (Ernest N. Morial Convention Center)
Polina Bellman, MD, Wei Cui, MD, Zahra Mahmoudjafari, PhD, Shebli Atrash, MD, Barry Paul, MD, MS, Hamza Hashmi, MD, Rajesh Banderudrappagari, Leyla O. Shune, MD, Al-Ola Abdallah, MD and Nausheen Ahmed, MD
Monday, December 12, 2022
702 Using Spatial Transcriptomics to Reveal Fetal Liver Hematopoietic Stem Cell-Niche Interactions
Session: 506. Bone Marrow Microenvironment: Extrinsic Regulators of Hematopoiesis
Symposia: Bone Marrow Microenvironment
Program: Oral and Poster Abstracts
Time: 10:30 AM-12:00 PM
Location: 260-262 (Ernest N. Morial Convention Center)
Ruochen Dong, PhD, BM, Jonathon Russell, Hua Li, Seth Malloy, Kate Hall, Kaitlyn Petentler, Allison Scott, Cathy Mckinney, Sarah E Smith, Yongfu Wang, Anoja Perera, Sean McKinney, Brian Slaughter, Jay Unruh, Xi C He and Linheng Li, PhD
714 Randomized Phase II Study to Assess the Role of Nivolumab As Single Agent to Eliminate Minimal Residual Disease and Maintain Remission in Acute Myelogenous Leukemia (AML) Patients after Chemotherapy (NCI9706 protocol; REMAIN Trial)
Session: 616. Acute Myeloid Leukemias: Investigational Therapies, Excluding Transplantation and Cellular Immunotherapies: Frontline and Maintenance
Symposia: Acute Myeloid Leukemias: Investigational Therapies, Excluding Transplantation and Cellular Immunotherapies
Program: Oral and Poster Abstracts
Time: 10:30 AM-12:00 PM
Location: 275-277 (Ernest N. Morial Convention Center)
Hongtao Liu, MD, PhD, Elad Sharon, MD, MPH, Theodore G. Karrison, PhD, Yuanyuan Zha, PhD, Noreen Fulton, BS, Howard Streicher, MD, Kendra Sweet, MD, George Yaghmour, MD, Jane Jijun Liu, MD, Brian A. Jonas, MD, PhD, Aaron D. Schimmer, MD, PhD, Steven Grant, MD, Amer M. Zeidan, MD, Gerhard C. Hildebrandt, MD, Christopher S. Hourigan, MD PhD, Christopher H. Lowrey, MD, Ryan J. Mattison, MD, Neil Palmisiano, MD, MS, Amandeep Salhotra, MD, Dimitrios Tzachanis, MD, PhD, Maria R. Baer, MD, Tara L. Lin, MD, Prapti Patel, MD, Helen Chen, MD, Walter M. Stadler, MD, Olatoyosi Odenike, MD, Richard A. Larson, MD, Thomas F. Gajewski, MD, PhD and Wendy Stock, MD
757 Fixed Duration Therapy with Daratumumab, Carfilzomib, Lenalidomide and Dexamethasone for High Risk Smoldering Multiple Myeloma-Results of the Ascent Trial
Session: 653. Myeloma and Plasma Cell Dyscrasias: Prospective Therapeutic Trials: Risk-adapted Treatment Strategies in Myeloma and Related Conditions
Symposia: Myeloma and Plasma Cell Dyscrasias: Prospective Therapeutic Trials
Program: Oral and Poster Abstracts
Time: 10:30 AM-12:00 PM
Location: 288-290 (Ernest N. Morial Convention Center)
Shaji K Kumar, MD, Melissa Alsina, MD, Betsy Laplant, MS, Ashraf Z. Badros, MD, Al-Ola Abdallah, MD, Rafat Abonour, MD, Erik J Asmus, Binod Dhakal, MBBS, Cara A. Rosenbaum, MD, Daniel Egan, MD, Manisha Bhutani, MD, Andrzej Jakubowiak, MD, PhD and Brian G.M. Durie, MD
766 Idecabtagene Vicleucel (Ide-cel) Chimeric Antigen Receptor (CAR) T-Cell Therapy in Patients with Relapsed/Refractory Multiple Myeloma (RRMM) Who Have Received a Prior BCMA-Targeted Therapy: Real World, Multi-Institutional Experience
Session: 705. Cellular Immunotherapies: Real World Outcomes and Special Populations Treated with Cellular Therapy
Symposia: Cellular Immunotherapies: Late Phase and Commercially Available Therapies
Program: Oral and Poster Abstracts
Time: 10:30 AM-12:00 PM
Location: 393-396 (Ernest N. Morial Convention Center)
Christopher J. Ferreri, MD, Michelle A.T. Hildebrandt, PhD, Hamza Hashmi, MD, Leyla O. Shune, MD, Joseph P. McGuirk, DO, Douglas W. Sborov, MD, Charlotte B Wagner, PharmD, M. Hakan Kocoglu, MD, Shebli Atrash, MD, Peter M. Voorhees, MD, Jack Khouri, MD, Danai Dima, MD, Aimaz Afrough, MD, Aishwarya Sannareddy, MBBS, Gary Simmons, DO, James Davis, PharmD, Nilesh Kalariya, Lauren C. Peres, PhD, MPH, Melissa Alsina, MD, Frederick L. Locke, MD, Surbhi Sidana, MD, Doris K. Hansen, MD, Krina Patel, MD, MSc and Omar Alexis Castaneda Puglianini, MD
834 A Risk-Adapted Study to Assess the Efficacy of Enasidenib and Subsequent Response-Driven Addition of Azacitidine for Newly Diagnosed IDH2-Mutant AML Patients: 3-Year Follow-up
Session: 615. Acute Myeloid Leukemias: Commercially Available Therapies, Excluding Transplantation and Cellular Immunotherapies: Advances in Mutation-targeted Therapy for AML
Symposia: Acute Myeloid Leukemias: Commercially Available Therapies, Excluding Transplantation and Cellular Immunotherapies
Program: Oral and Poster Abstracts
Time: 2:45 PM-4:15 PM
Location: R02-R05 (Ernest N. Morial Convention Center)
Eytan Stein, MD, Sheng F Cai, MD, PhD, Ying Huang, MS, MA, Andrew Dunbar, MD, Maria R. Baer, MD, Wendy Stock, MD, Tibor Kovacsovics, MD, William G. Blum, MD, Gary J. Schiller, MD, Rebecca L. Olin, MD, James M. Foran, MD, Mark R. Litzow, MD, Tara L. Lin, MD, Prapti A. Patel, MD, Matthew C. Foster, MD, Michael M. Boyiadzis, MD, Robert H. Collins, M.D., Jordan Chervin, Abigail B. Shoben, PhD, Jo-Anne Vergilio, MD, Nyla A. Heerema, PhD, Leonard Rosenberg, PhD RPh, Timothy Chen, PhD, Ashley O. Yocum, PhD, Franchesca Druggan, MSc, Sonja Marcus, MPH, Mona Stefanos, Molly Martycz, Brian J. Druker, Alice S. Mims, MD, Uma Borate, MD, Amy Burd, PhD29, John C. Byrd, MD and Ross L. Levine, MD
874 Mgta-117, an Anti-CD117 Antibody-Drug Conjugated with Amanitin, in Participants with Relapsed/Refractory Adult Acute Myeloid Leukemia (AML) and Myelodysplasia with Excess Blasts (MDS-EB): Safety, Pharmacokinetics and Pharmacodynamics Initial Findings from a Phase 1/2 Study
Session: 721. Allogeneic Transplantation: Conditioning Regimens, Engraftment and Acute Toxicities II
Symposia: Allogeneic Transplantation: Conditioning Regimens, Engraftment and Acute Toxicities
Program: Oral and Poster Abstracts
Time: 2:45 PM-4:15 PM
Location: 393-396 (Ernest N. Morial Convention Center)
Peter Westervelt, MD PhD, Partow Kebriaei, MD, Mark Juckett, MD, Andrew S. Artz, MD, MS, Onyee Chan, MD, Philip L. McCarthy, MD, Sherif S Farag, MD, PhD, Anurag K. Singh, MD, Eytan Stein, MD, Jeffrey Humphrey, MD, William Baeder, MPH, Ji Hyun Lee, MD, MPH, Alison Occhiuti, MS, Jeanie Tang, BS, David Santos, BS10*, Kirk Bertelsen, PhD1, Balaji Mahender, BPharm, MS, Nicole Henry, BSN, RN and Shawn Rose, MD, PhD
3807 Netosis and the Formation of Neutrophil Extracellular Traps (NETs) in Patients with Severe and Critical COVID-19 May Contribute to Disease Progression and Thrombosis
Session: 331. Thrombotic Microangiopathies/Thrombocytopenias and COVID-19-related Thrombotic/Vascular Disorders: Clinical and Epidemiological: Poster III
Symposia: Thrombotic Microangiopathies/Thrombocytopenias and COVID-19-related Thrombotic/Vascular Disorders: Clinical and Epidemiological
Program: Oral and Poster Abstracts
Time: 6 PM-8 PM
Location: Hall D (Ernest N. Morial Convention Center)
Noritaka Yada, Quan Zhang, Antonia Bignotti, B.A., Liang Zheng, Ph.D., Zhan Ye, M.D., Ph.D. and X. Long Zheng, MD, PhD
3846 Characterization of Dynamic Niche Signaling Modules during Embryonic Hematopoietic Development Using Spatial Transcriptomics
Session: 501. Hematopoietic Stem and Progenitor Cells and Hematopoiesis: Basic and Translational: Poster III
Symposia: Hematopoietic Stem and Progenitor Cells and Hematopoiesis: Basic and Translational
Program: Oral and Poster Abstracts
Time: 6 PM-8 PM
Location: Hall D (Ernest N. Morial Convention Center)
Xinjian Mao, PhD, Ning Zhang, PhD, Kate Hall, Kaitlyn Petentler, Allison Scott, Seth Malloy, Fang Liu, Kevin Ferro, Jessica Bell, Erin Hamilton, Jeffrey Haug, Yongfu Wang, Hua Li, Anoja Perera, Jay Unruh, Brian Slaughter, Xi C He, Nancy Speck, PhD and Linheng Li, PhD
4009 Premedication and Therapeutic Drug Monitoring (TDM) for Pegaspargase: A Prospective Multicenter Multi-Ethnic Study of Pediatric and Adolescent Patients
Session: 612. Acute Lymphoblastic Leukemias: Clinical and Epidemiological: Poster III
Symposia: Acute Lymphoblastic Leukemias: Clinical and Epidemiological
Program: Oral and Poster Abstracts
Time: 6 PM-8 PM
Location: Hall D (Ernest N. Morial Convention Center)
Van T Huynh, MD, Sonia Morales, MD, Anurag K. Agrawal, MD, Christine L. Phillips, MD, Keith J August, MD, MS, Erin Guest, MD, Beth Apsel Winger, MD, PhD, Catherine Aftandilian, MD, Janel R. Long-Boyle, PharmD, PhD, Kirsten Kasper, BA, Keri Zabokrtsky, MS and Carol Hwang Lin, MD
4091 A Multi-Center Phase Ib Trial of the Histone Deactylase Inhibitor (HDACi) Entinostat in Combination with Anti-PD1 Antibody Pembrolizumab in Patients with Refractory/Relapsed Myelodysplastic Syndromes (RR-MDS) or Oligoblastic Acute Myeloid Leukemia (RR-AML) after Hypomethylating Agent (HMA) Failure
Session: 612. Acute Lymphoblastic Leukemias: Clinical and Epidemiological: Poster III
Symposia: Acute Myeloid Leukemias: Investigational Therapies, Excluding Transplantation and Cellular Immunotherapies
Program: Oral and Poster Abstracts
Time: 6 PM-8 PM
Location: Hall D (Ernest N. Morial Convention Center)
Jan Philipp Bewersdorf, MD, Rory M. Shallis, MD, Elad Sharon, MD, MPH, Anne Caldwell, Wei Wei, MD, Abdulraheem Yacoub, MD, Yazan F. Madanat, MD, Joshua F. Zeidner, MD, Jessica K. Altman, MD, Olatoyosi Odenike, MD, Swaroopa Yerrabothala, MD, Tibor Kovacsovics, MD, Nikolai A. Podoltsev, MD, PhD, Stephanie Halene, MD, Richard F. Little, MD, MPH, Richard Piekarz, MD, PhD, MS, BA, Steven D. Gore, MD, Tae Kon Kim, MD and Amer M. Zeidan, MD
4085 A Phase 1b Dose Escalation and Expansion Study of SNDX-5613, Azacitidine (AZA) and Venetoclax (VEN) in Newly Diagnosed, Patients ≥ 60 Years with Untreated NPM1-Mutated/ FLT3-Wild Type AML or KMT2A-Rearranged Acute Myeloid Leukemia (AML)
Session: 616. Acute Myeloid Leukemias: Investigational Therapies, Excluding Transplantation and Cellular Immunotherapies: Poster III
Symposia: Acute Myeloid Leukemias: Investigational Therapies, Excluding Transplantation and Cellular Immunotherapies
Program: Oral and Poster Abstracts
Time: 6 PM-8 PM
Location: Hall D (Ernest N. Morial Convention Center)
Joshua F. Zeidner, MD, Matthew C. Foster, MD, Mary Johnson, Ying Huang, MS, MA, Ronan T. Swords, MD, Eytan Stein, MD, James M. Foran, MD, Maria R. Baer, MD, Wendy Stock, MD, Yazan F. Madanat, MD, Tibor Kovacsovics, MD, Rebecca L. Olin, MD, William G. Blum, MD, Gary J. Schiller, MD, Tara L. Lin, MD, Robert L. Redner, MD, Zeina Al-Mansour, MD, Emily K Curran, MD, Nyla A. Heerema, PhD, Molly Martycz, Leonard Rosenberg, PhD RPh, Sonja Marcus, MPH, Ashley O. Yocum, PhD, Timothy Chen, PhD, Mona Stefanos, Franchesca Druggan, MSc, Amy Burd, PhD, Ross L. Levine, MD, Brian J. Druker, Uma Borate, MD, John C. Byrd, MD and Alice S. Mims, MD
2759 Entospletinib (ENTO) in Combination with Cytarabine (Ara-C) and Daunorubicin (DNR) in Newly Diagnosed (ND) Adult Patients with NPM1-Mutated and FLT3-ITD Wild-Type Acute Myeloid Leukemia (AML) Is Associated with Good Response and Survival: A Phase 2 Sub-Study of the Beat AML Master Trial
Session: 616. Acute Myeloid Leukemias: Investigational Therapies, Excluding Transplantation and Cellular Immunotherapies: Poster II
Symposia: Acute Myeloid Leukemias: Investigational Therapies, Excluding Transplantation and Cellular Immunotherapies
Program: Oral and Poster Abstracts
Time: 6 PM-8 PM
Location: Hall D (Ernest N. Morial Convention Center)
Uma Borate, MD, Rui Li, MPH, Ying Huang, MS, MA, Ronan T. Swords, MD, Elie Traer, MD, PhD, Eytan Stein, MD, James M. Foran, MD, Maria R. Baer, MD, Vu H. Duong, MD, MS, Wendy Stock, MD, Olatoyosi Odenike, MD, Prapti Patel, MD, Robert H. Collins, M.D., Yazan F. Madanat, MD, Tibor Kovacsovics, MD, Michael W. Deininger, MD, PhD, Catherine Smith, MD, Rebecca L. Olin, MD, Martha L. Arellano, MD, William G. Blum, MD, Gary J. Schiller, MD, Tara L. Lin, MD, Matthew C. Foster, MD, Michael M. Boyiadzis, MD, Robert L. Redner, MD, Zeina Al-Mansour, MD, Emily K Curran, MD, Nyla A. Heerema, PhD, Theophilus J Gana, MD PhD, Molly Martycz, Leonard Rosenberg, PhD RPh, Sonja Marcus, MPH, Ashley O. Yocum, PhD, Timothy Chen, PhD, Mona Stefanos, Franchesca Druggan, MSc, Amy Burd, PhD, Ross L. Levine, MD, Brian J. Druker, John C. Byrd, MD and Alice S. Mims, MD
2760 Updated Results from a Phase 1 Study of APVO436, a Novel Bispecific Anti-CD123 x Anti-CD3 Adaptir™ Molecule, in Relapsed/Refractory Acute Myeloid Leukemia and Myelodysplastic Syndrome
Session: 616. Acute Myeloid Leukemias: Investigational Therapies, Excluding Transplantation and Cellular Immunotherapies: Poster II
Symposia: Acute Myeloid Leukemias: Investigational Therapies, Excluding Transplantation and Cellular Immunotherapies
Program: Oral and Poster Abstracts
Time: 6 PM-8 PM
Location: Hall D (Ernest N. Morial Convention Center)
Justin Watts, MD, Michael Maris, MD, Tara L. Lin, MD, Prapti Patel, MD, Yazan F. Madanat, MD, Christopher R. Cogle, MD, Gautam Borthakur, MD, Dirk Huebner, MD, Noor Khaskhely, MD, Lynn Bonham, PhD, Monica Massaro, MPH, Daphne Taylor, CPA, Caroline Taromino, MBA and Alice S. Mims, MD
4133 A Robust Long Non-Coding RNA Expression Classifier for Risk Stratification in Pediatric AML
Session: 617. Acute Myeloid Leukemias: Biomarkers, Molecular Markers and Minimal Residual Disease in Diagnosis and Prognosis: Poster III
Symposia: Acute Myeloid Leukemias: Biomarkers, Molecular Markers and Minimal Residual Disease in Diagnosis and Prognosis
Program: Oral and Poster Abstracts
Time: 6 PM-8 PM
Location: Hall D (Ernest N. Morial Convention Center)
Jason E Farrar, MD, Jenny L. Smith, MSc, MEd, Megan Othus, PhD, Benjamin J. Huang, MD, Yi-Cheng Wang, MS, Rhonda E. Ries, MA, Tiffany A. Hylkema, BS, Era L Pogosova-Agadjanyan, BS, Sneha Challa, MS, Amanda R. Leonti, MS, Timothy I. Shaw, PhD, Timothy Junius Triche Jr., PhD, Alan S. Gamis, MD, MPH, Richard Aplenc, MD, PhD, Anders E. Kolb, MD, Xiaotu Ma, PhD, Derek Stirewalt, MD, Todd A. Alonzo, PhD and Soheil Meshinchi, M.D., Ph.D.
4264 Phase 1b Trial of Cereblon-Modulating Agents Iberdomide and CC-99282 Plus R-CHOP in Previously Untreated Aggressive B-Cell Lymphoma
Session: 626. Aggressive Lymphomas: Prospective Therapeutic Trials: Poster III
Symposia: Aggressive Lymphomas: Prospective Therapeutic Trials
Program: Oral and Poster Abstracts
Time: 6 PM-8 PM
Location: Hall D (Ernest N. Morial Convention Center)
Jason Westin, MD, Alejandro Martín García-Sancho, MD, PhD, Marc Hoffmann, MD, Theodoros P. Vassilakopoulos, MD, Su-Peng Yeh, MD, Argyrios Gkasiamis, MD, Poliana Patah, Arpankumar Patel, Ju Li, PhD and Grzegorz S. Nowakowski, MD
4357 Exploratory Predictors for Hydroxyurea Treatment Duration in Polycythemia Vera: A Retrospective Multi-Institutional Database Analysis
Session: 634. Myeloproliferative Syndromes: Clinical and Epidemiological: Poster III
Symposia: Myeloproliferative Syndromes: Clinical and Epidemiological
Program: Oral and Poster Abstracts
Time: 6 PM-8 PM
Location: Hall D (Ernest N. Morial Convention Center)
Chen Zhang, MD, Douglas Tremblay, MD, John Magnotti, PhD, Lukas Ronner, MD MSCR, Nikolai A. Podoltsev, MD, PhD5, Jason Gotlib, MD, MS6, Mark L. Heaney, MD7, Andrew Kuykendall, MD, Casey L. O'Connell, MD, Angela G Fleischman, MD, PhD, Ruben Mesa, MD, FACP, Abdulraheem Yacoub, MD, John Mascarenhas, MD and Jamile M. Shammo, MD
4357 Exploratory Predictors for Hydroxyurea Treatment Duration in Polycythemia Vera: A Retrospective Multi-Institutional Database Analysis
Session: 634. Myeloproliferative Syndromes: Clinical and Epidemiological: Poster III
Symposia: Myeloproliferative Syndromes: Clinical and Epidemiological
Program: Oral and Poster Abstracts
Time: 6 PM-8 PM
Location: Hall D (Ernest N. Morial Convention Center)
Chen Zhang, MD, Douglas Tremblay, MD, John Magnotti, PhD, Lukas Ronner, MD MSCR, Nikolai A. Podoltsev, MD, PhD5, Jason Gotlib, MD, MS6, Mark L. Heaney, MD7, Andrew Kuykendall, MD, Casey L. O'Connell, MD, Angela G Fleischman, MD, PhD, Ruben Mesa, MD, FACP, Abdulraheem Yacoub, MD, John Mascarenhas, MD and Jamile M. Shammo, MD
4368 A Phase 2 Study of the LSD1 Inhibitor Bomedemstat (IMG-7289) for the Treatment of Advanced Myelofibrosis (MF): Updated Results and Genomic Analyses
Session: 634. Myeloproliferative Syndromes: Clinical and Epidemiological: Poster III
Symposia: Myeloproliferative Syndromes: Clinical and Epidemiological
Program: Oral and Poster Abstracts
Time: 6 PM-8 PM
Location: Hall D (Ernest N. Morial Convention Center)
Kristen M. Pettit, Harinder Gill, MD, MBBS, FRCP, FRCPath, Abdulraheem Yacoub, MD, Terrence Bradley, MD, Aaron T. Gerds, MD, MS, Maciej Tatarczuch, BMBS, Jake Shortt, FRACP, FRCPA, PhD, Natasha Joan Curtin, MD, FRACP, FRCPA, James M. Rossetti, DO, Kate Burbury, MBBS, FRACP, FRCPA, DPhil, Adam J Mead, MD PhD, Joachim R Göthert, MD, Steffen Koschmieder, Matt Reyer, PhD, Benjamin Siranosian, PhD, Georges Natsoulis, Ph.D., William S Stevenson, MBBS, PhD, FRACP, FRCPA, Joanne Ewing, MD, PhD, Joseph M. Chacko, MD, MBBS, BSc, FRCP, FRCPath, Elisa Rumi, Anna B. Halpern, MD, Francesca Palandri, PhD, MD, Nicola Vianelli, MD, Francesco Passamonti, MD, Ruben Mesa, MD, FACP, Monia Marchetti, Claire N. Harrison, DM, Alessandro M. Vannucchi, Justin Watts, MD, David M Ross, MBBS, PhD, FRACP, FRCPA, Moshe Talpaz, MD and Hugh Young Rienhoff Jr., MD
4562 Sea-BCMA Mono- and Combination Therapy in Patients with Relapsed/Refractory Multiple Myeloma: Updated Results of a Phase 1 Study (SGNBCMA-001)
Session: 653. Myeloma and Plasma Cell Dyscrasias: Prospective Therapeutic Trials: Poster III
Symposia: Myeloma and Plasma Cell Dyscrasias: Prospective Therapeutic Trials
Program: Oral and Poster Abstracts
Time: 6 PM-8 PM
Location: Hall D (Ernest N. Morial Convention Center)
James E. Hoffman, MD, Brea Lipe, MD, Jason Melear, MD, Michaela Liedtke, MD, Mark A. Schroeder, MD, Ruben Niesvizky, MD, Christopher Strouse, MD, Christopher A. Yasenchak, MD, Damian J. Green, MD, Jeremy Sauer, PhD, Yinghui Wang, MS, Phoenix Ho, MD and Al-Ola Abdallah, MD
4629 CTX110 Allogeneic CRISPR-Cas9–Engineered CAR T Cells in Patients (Pts) with Relapsed or Refractory (R/R) Large B-Cell Lymphoma (LBCL): Results from the Phase 1 Dose Escalation Carbon Study
Session: 704. Cellular Immunotherapies: Early Phase and Investigational Therapies: Poster III
Symposia: Cellular Immunotherapies: Early Phase and Investigational Therapies
Program: Oral and Poster Abstracts
Time: 6 PM-8 PM
Location: Hall D (Ernest N. Morial Convention Center)
Joseph P. McGuirk, DO, Constantine S. Tam, Nicolaus Kröger, MD, Peter A. Riedell, MD, Hemant S. Murthy, MD, Phoebe Joy Ho, MBBS(Syd) DPhil(Oxon) FRACP FRCPA FFSc(RCPA), Joseph E. Maakaron, MD, Edmund K. Waller, MD, PhD, Farrukh T. Awan, M.D., Paul J. Shaughnessy, MD, Armin Ghobadi, MD, Michael R. Bishop, MD, Ana Alfonso-Pierola, MD, PhD, Michael Dickinson, MD, Praveen Ramakrishnan Geethakumari, MD, MS, Ainsley Ross, MPH, William Stevens, MS, Huansheng Xu, PhD, Anna Ma, MS, Sarah Beaussant Cohen, MD, Richard T. Maziarz, MD and Carlos Bachier, MD
4659 Idecabtagene Vicleucel Chimeric Antigen Receptor T-Cell Therapy for Relapsed/Refractory Multiple Myeloma with Renal Insufficiency: Real World Experience
Session: 705. Cellular Immunotherapies: Late Phase and Commercially Available Therapies: Poster III
Symposia: Cellular Immunotherapies: Late Phase and Commercially Available Therapies
Program: Oral and Poster Abstracts
Time: 6 PM-8 PM
Location: Hall D (Ernest N. Morial Convention Center)
Surbhi Sidana, MD, Lauren C. Peres, PhD, MPH, Hamza Hashmi, MD, Hitomi Hosoya, MD, PhD, Christopher J. Ferreri, MD, Shebli Atrash, MD, Jack Khouri, MD, Peter M. Voorhees, MD, Danai Dima, MD, Gary Simmons, DO, Nilesh Kalariya, Vanna Hovanky, Sushma Bharadwaj, MD, MS, Sally Arai, MD, David B. Miklos, MD, PhD, Charlotte B Wagner, PharmD, James Davis, PharmD, Douglas W. Sborov, MD, Taiga Nishihori, MD, Melissa Alsina, MD, Frederick L. Locke, MD, Rebecca Gonzalez, PharmD, BCOP, M. Hakan Kocoglu, MD, Aishwarya Sannareddy, MBBS, Aimaz Afrough, MD, Joseph P. McGuirk, DO, Leyla O. Shune, MD, Krina Patel, MD, MSc and Doris K. Hansen, MD
4662 Standard Cytogenetic Risk Stratification Is Not Predictive of CD19 CAR Outcomes and Impact of Disease Burden Varies between Cytogenetic Risk Groups
Session: 705. Cellular Immunotherapies: Late Phase and Commercially Available Therapies: Poster III
Symposia: Cellular Immunotherapies: Late Phase and Commercially Available Therapies
Program: Oral and Poster Abstracts
Time: 6 PM-8 PM
Location: Hall D (Ernest N. Morial Convention Center)
John C. Molina, MD, MEd, Vasant Chinnabhandar, MD, MBBS, Vanessa A Fabrizio, MD, Michael Kunicki, Holly Pacenta, MD, Jenna Rossoff, MD, Heather E Stefanski, MD, Julie Talano, MD, Amy Moskop, MD, MS, Michael R Verneris, MD, Gary Douglas Myers, MD, Nicole Karras, MD, Christina Baggott, RN, PhD, Muna Qayed, MD, MSc, Michelle L. Hermiston, MD, PhD, Prakash Satwani, MD, Christa Krupski, DO, MPH, Amy K. Keating, MD, Susanne H.C. Baumeister, MD, Kevin J. Curran, MD, Crystal L. Mackall, MD, Theodore W. Laetsch, MD, Liora M. Schultz, MD and Stephanie M. Smith, MD
4674 Obesity Associates with Inferior Outcomes and Toxicity in Pediatric and Young Adult Patient with Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia Treated with Commercially Manufactured Tisagenlecleucel
Session: 705. Cellular Immunotherapies: Late Phase and Commercially Available Therapies: Poster III
Symposia: Cellular Immunotherapies: Late Phase and Commercially Available Therapies
Program: Oral and Poster Abstracts
Time: 6 PM-8 PM
Location: Hall D (Ernest N. Morial Convention Center)
Anthony J Ross, MD, Christina Baggott, RN, PhD, Snehit Prabhu, PhD, Holly Pacenta, MD, Christine Philips, Jenna Rossoff, MD, Heather E Stefanski, MD, Julie Talano, MD, Amy Moskop, MD, MS, Susanne H.C. Baumeister, MD, Michael R Verneris, MD, Gary Douglas Myers, MD, Nicole Karras, MD, Muna Qayed, MD, MSc, Michelle L. Hermiston, MD, PhD, Prakash Satwani, MD, Christa Krupski, DO, MPH, Amy K. Keating, MD, Rachel Wilcox, Vanessa A Fabrizio, MD, Vasant Chinnabhandar, MD, Kevin J. Curran, MD, Crystal L. Mackall, MD, Theodore W. Laetsch, MD, Sandra K Althouse, PhD, Shannon L. Maude, MD, PhD, Curtis J Henry, PhD, Liora M. Schultz, MD and Jodi L. Skiles, MD
4677 Absolute Lymphocyte Count and Outcomes of Multiple Myeloma Patients Treated with Idecabtagene Vicleucel: The U.S. Myeloma CAR T Consortium Real World Experience
Session: 705. Cellular Immunotherapies: Late Phase and Commercially Available Therapies: Poster III
Symposia: Cellular Immunotherapies: Late Phase and Commercially Available Therapies
Program: Oral and Poster Abstracts
Time: 6 PM-8 PM
Location: Hall D (Ernest N. Morial Convention Center)
Jack Khouri, MD, Hong Li, MS, Doris K. Hansen, MD, Surbhi Sidana, MD, Leyla O. Shune, MD, Shaun DeJarnette, Faiz Anwer, MD, Douglas W Sborov, Charlotte B Wagner, PharmD, M. Hakan Kocoglu, MD, Shebli Atrash, MD, Peter M. Voorhees, MD, Jason Valent, MD, Lauren C. Peres, PhD, MPH, Vanna Hovanky, Gary Simmons, DO, Danai Dima, MD, Nilesh Kalariya, Aimaz Afrough, MD, Gurbakhash Kaur, MD, Aishwarya Sannareddy, MBBS, Christopher J. Ferreri, MD, James Davis, PharmD, Joseph P. McGuirk, DO, Frederick L. Locke, MD, Rachid C. Baz, MD, Betty K. Hamilton, MD, Melissa Alsina, MD, Craig S. Sauter, MD, Hamza Hashmi, MD and Krina Patel, MD, MSc
4686 PLX-R18 (Avoplacel), a Placental Expanded Mesenchymal-like Stromal Cell Therapy Shows Favorable Safety and Appears to Improve Incomplete Hematopoietic Recovery after Hematopoietic Cell Transplantation (HCT)
Session: 721. Allogeneic Transplantation: Conditioning Regimens, Engraftment and Acute Toxicities: Poster III
Symposia: Allogeneic Transplantation: Conditioning Regimens, Engraftment and Acute Toxicities
Program: Oral and Poster Abstracts
Time: 6 PM-8 PM
Location: Hall D (Ernest N. Morial Convention Center)
Hillard M Lazarus, MD, Joseph P. McGuirk, DO, Tsila Zuckerman, MD, Leland Metheny, MD, Luis Pineiro, MD, Mark R. Litzow, MD, Scott D. Rowley, MD, Batia Avni, Roni Tamari, MD, Michal Sheleg, PhD, Daniel Rothenstein, PhD, Nitsan Halevy, MD and Jacob M. Rowe, MB, BS.
4703 Lessons Learned from COVID-19 Pandemic: Outcomes after Sars-Cov-2 Infection in Hematopoietic Cell Transplant and Cell Therapy Recipients
Session: 721. Allogeneic Transplantation: Conditioning Regimens, Engraftment and Acute Toxicities: Poster III
Symposia: Allogeneic Transplantation: Conditioning Regimens, Engraftment and Acute Toxicities
Program: Oral and Poster Abstracts
Time: 6 PM-8 PM
Location: Hall D (Ernest N. Morial Convention Center)
Muhammad Umair Mushtaq, MD, Joe S Al-Ramahi, MD, Kevin S Li, Moazzam Shahzad, MD, Sibgha Gull Chaudhary, MD, Ramesh Balusu, PhD, Nausheen Ahmed, MD, Rajat Bansal, MD, Haitham Abdelhakim, MD, Leyla O. Shune, MD, Anurag K. Singh, MD, Sunil H Abhyankar, MD and Joseph P. McGuirk, DO
4709 Neihulizumab (ALTB-168) in Patients with Steroid-Refractory Acute Graft-Versus-Host-Disease (SR-aGVHD) or Treatment-Refractory Acute Graft-Versus-Host-Disease (TR-aGVHD)
Session: 722. Allogeneic Transplantation: Acute and Chronic GVHD, Immune Reconstitution: Poster III
Symposia: Allogeneic Transplantation: Acute and Chronic GVHD, Immune Reconstitution
Program: Oral and Poster Abstracts
Time: 6 PM-8 PM
Location: Hall D (Ernest N. Morial Convention Center)
Sameem Abedin, MD, Mehdi Hamadani, MD, Shernan G Holtan, MD, Gary J. Schiller, MD, Molly Gallogly, MD, PhD, Edmund K. Waller, MD, PhD, Satyajit Kosuri, MD, Sunil H Abhyankar, MD, Sarah M. Anand, MD, Mahasweta Gooptu, MD, Iming Cho, PhD, Simona Reed, PhD, Shih-Yao Lin, MD, PhD, Jesse W Hall, MD and Paul J Martin, MD
4731 Quality of Life in Patients Undergoing Double Umbilical Cord Blood Vs. Haploidentical Marrow Transplantation: A QOL Analysis Report of BMT CTN 1101
Session: 723. Allogeneic Transplantation: Long-term Follow-up and Disease Recurrence: Poster III
Symposia: Allogeneic Transplantation: Long-term Follow-up and Disease Recurrence
Program: Oral and Poster Abstracts
Time: 6 PM-8 PM
Location: Hall D (Ernest N. Morial Convention Center)
Najla El Jurdi, MD, Michael Martens, PhD, Claudio G. Brunstein, MD, PhD, Paul O'Donnell, MD, Stephanie J. Lee, MD, MPH, Anita D'Souza, MD, MS, Brent Logan, PhD, Sanghee Hong, MD, Karam Sandhu, Roman M Shapiro, MD, Anurag K. Singh, MD, Mary M. Horowitz, MD, MS and Betty K. Hamilton, MD
4750 Outcomes of Patients with Relapsed/Refractory Multiple Myeloma (RRMM) Who Responded to Daratumumab, Pomalidomide and Dexamethasone (DPd), Followed By High Dose Chemotherapy/Autologous Stem Cell Transplantation (HDCT/ASCT) Versus (DPd) Alone
Session: 731. Autologous Transplantation: Clinical and Epidemiological: Poster III
Symposia: Autologous Transplantation: Clinical and Epidemiological
Program: Oral and Poster Abstracts
Time: 6 PM-8 PM
Location: Hall D (Ernest N. Morial Convention Center)
Jayanshu Jain, MD, Ghena Khasawneh, MBBS, Hamza Hashmi, MD, Meera Mohan, MD, Zahra Mahmoudjafari, PhD, Wei Cui, MD, Joseph P. McGuirk, DO, Leyla O. Shune, MD, Nausheen Ahmed, MD, Al-Ola Abdallah, MD and Shebli Atrash, MD
4929 Cytokine Release Syndrome (CRS) Is Not Required for CAR-T Cell Efficacy in Aggressive Large B-NHL Clinically Relevant Abstract
Session: 905. Outcomes Research—Lymphoid Malignancies: Poster III
Symposia: Outcomes Research—Lymphoid Malignancies
Program: Oral and Poster Abstracts
Time: 6 PM-8 PM
Location: Hall D (Ernest N. Morial Convention Center)
Shakthi Bhaskar, MD, Vivek Patel, MD, David L. Porter, MD, Stephen J. Schuster, MD, Loretta J. Nastoupil, MD, Miguel-Angel Perales, MD, Ana Alarcon Tomas, Michael R. Bishop, MD, Joseph P. McGuirk, DO, Richard T. Maziarz, MD, Andy Chen, MD, PhD, Veronika Bachanova, MD, PhD, Peter A. Riedell, MD and Olalekan O. Oluwole, MBBS
Tuesday, December 13, 2022
LBA-1 Consolidation Therapy with Blinatumomab Improves Overall Survival in Newly Diagnosed Adult Patients with B-Lineage Acute Lymphoblastic Leukemia in Measurable Residual Disease Negative Remission: Results from the ECOG-ACRIN E1910 Randomized Phase III National Cooperative Clinical Trials Network Trial
Session: Late Breaking Abstracts
Program: Oral and Poster Abstracts
Time: 9 AM-10:30 AM
Location: Hall E (Ernest N. Morial Convention Center)
Mark R. Litzow, MD, Zhuoxin Sun, PhD, Elisabeth Paietta, PhD, Ryan J. Mattison, MD, Hillard M Lazarus, MD, Jacob M. Rowe, MB, BS, Daniel A. Arber, MD, Charles G. Mullighan, MBBS, MD, Cheryl L Willman, MD, Yanming Zhang, MD, Matthew Wieduwilt, MD, Michaela Liedtke, MD, Julie Bergeron, MD, Keith W. Pratz, MD, Shira Dinner, MD, Noelle V. Frey, MD, MS, Steven D. Gore, MD, Bhavana Bhatnagar, DO, Ehab L. Atallah, MD, Geoffrey L. Uy, MD, Deepa Jeyakumar, MD, Tara L. Lin, MD, Richard F. Little, MD, MPH, Selina M. Luger, MD, FRCPC and Martin S. Tallman, MD -
December 6, 2022
GS1-01 Race and clinical outcomes in the RxPONDER trial (SWOG S1007)
General Session #1
Location: Hall #3
Date: Tuesday, Dec 6, 2:00 - 2:15 PM
Abdou Y, Barlow WE, Gralow JR, Meric-Bernstam F, Albain KS, Hayes DF, Lin NU, Perez EA, Goldstein LJ, Chia SK, Dhesy-Thind S, Rastogi P, Alba E, Delaloge S, Schott AF, Shak S, Sharma P, Lew DL, Miao J, Unger JM, Tripathy D, Pusztai L, Hortobagyi GN, Kalinsky K.
GS1-04 Patient-reported cognitive impairment in women participating in the RxPONDER trial (SWOG S1007) by menopausal status
General Session #1
Location: Hall #3
Date: Tuesday, Dec 6, 2:45 - 3:00 PM
Kang I, Forschmiedt JK, Loch MM, Barlow WE, Lew DL, Gralow JR, Meric-Bernstam F, Albain KS, Hayes DF, Lin NU, Perez EA, Goldstein LJ, Rastogi P, Schott AF, Shak S, Sharma P, Miao J, Tripathy D, Pusztai L, Hortobagyi GN, Kalinsky K, Henry NL.
GS1-07 Results from a phase III randomized, placebo-controlled clinical trial evaluating adjuvant endocrine therapy +/- 1 year of everolimus in patients with high-risk hormone receptor-positive, HER2-negative breast cancer: SWOG S1207
General Session #1
Location: Hall #3
Date: Tuesday, Dec 6, 3:30 - 3:45 PM
Chavez-MacGregor M, Miao J, Pusztai L, Goetz MP, Rastogi P, Ganz PA, Mamounas EP, Paik S, Bandos H, Razaq W, O'Dea A, Kaklamani V, Silber ALM, Flaum LE, Andreopolu E, Baar J, Wendt AG, Careny JF, Sharma P, Gralow JR, Lew DL, Barlow WE, Hortobagyi GN.
PD1-06 Black patients with triple negative breast cancer (TNBC) have enriched stromal tumor infiltrating lymphocytes (sTILs) and receive preferential benefit from neoadjuvant immunotherapy
Session: Spotlight Poster Discussion 1 – Racial Outcomes and Disparities
Date: Tuesday, Dec 6, 5:00 PM
Stecklein SR, Yoder R, Salgado R, Staley JM, O'Dea A, Nye L, Elia M, Satelli D, Crane G, McKittrick R, Godwin AK, Khan Q, Sharma P.
P1-13-08 Inhibition of RNA binding protein HuR function sensitizes the TNBC to chemotherapy
Session: Poster Session #1 Treatment - Adjuvant Therapy: Adjuvant Chemotherapy
Date: Tuesday, Dec 6, 5:00 PM
Wei L, Zhang Q, Zhong C, Aubé J, Welch DR, Wu X, Xu L.
December 7, 2022
P2-11-11 Computer analysis of nuclear morphology with multiple instance learning predicts overall survival for node positive breast cancer patients from SWOG S8814: A blinded validation study
Session: Poster Session #2 Treatment - Adjuvant Therapy: Adjuvant Therapy - Targeted
Date: Wednesday, Dec 7, 7:00 AM
Shao D, Barlow WE, Li H, Lu C, Albain KS, Rae J, Hayes DF, Godwin AK, Thonpson AM, Madabhushi A, Pusztai L.
P2-11-16 Computerized measurements of nuclear morphology features, mitosis rate, and tubule formation from H&E images predicts disease-free survival in patients with HR+ & LN+ invasive breast cancer from SWOG S8814
Session: Poster Session #2 Treatment - Adjuvant Therapy: Adjuvant Therapy - Targeted
Date: Wednesday, Dec 7, 7:00 AM
Chen Y, Barlow WE, Li H, Lu C, Janowczyk A, Corredor G, Ganesan S, Feldman M, Fu P, Gilmore H, Albain KS, Pusztai L, Rae J, Hayes D, Godwin AK, Thompson AM, Madabhushi A.
P2-20-11 Progesterone impacts the growth and immune cell infiltration of murine mammary gland tumors
Session: Poster Session #2 Treatment - Adjuvant Therapy: Adjuvant Therapy - Targeted
Date: Wednesday, Dec 7, 7:00 AM
Werner LR, Helm DE, Tinoco J, Chowanec EI, Holloran SM, Hastings RC, Wei J, Lei G, Yang X-Y, Markiewicz MA, Chalise P, Balko JM, Hartman ZC, Hagan CR.
HER2-19 Impact of HER2 low status on clinical outcomes in participants with 1-3 positive lymph nodes, HR+/HER2- breast cancer with recurrence score
Session: HER2 Low: A Separate Entity Special Session
Location: Hall 3
Date: Wednesday, Dec 7, 9:45 - 11:00 AM
Spring LM, Barlow WE, Bardia A, Sharma P, Pusztai L, Hortobagyi GN, Kalinsky K.
P3-07-08 Exposure-adjusted incidence rates (EAIRs) of adverse events (AEs) from the phase 3 TROPiCS-02 study of sacituzumab govitecan (SG) vs treatment of physician’s choice (TPC) in HR+/HER2- metastatic breast cancer (MBC)
Session: Poster Session #3 - Treatment - Advanced Disease Treatment: Advanced Endocrine Therapy
Date: Wednesday, Dec 7, 5:00 PM
Tolaney SM, Schmid P, Bardia A, Marmé F, Loirat D, Sharma P, Wang H, Fu O, Verret W, Rugo HS.
December 8, 2022
PD11-07 Association of TNBC-DX scores with outcomes in triple-negative breast cancer (TNBC) treated with neoadjuvant pembrolizumab and chemotherapy: a correlative analysis from NeoPACT and NeoSTOP trials
Session: Spotlight Poster Discussion 11 – Improving Outcome for TNBC: New Directions in Immunotherapy
Date: Thursday, Dec 8, 7:00 AM
Sharma P, Stecklein SR, Yoder R, Staley JM, Salgado R, Paré; Conte B, Brasó-Maristany F, O'Dea A, Nye L, Elia M, Satelli D, Crane G, McKittrick R, Khan Q, Godwin AK, Prat A.
GS3-06 Palbociclib After CDK4/6i and Endocrine Therapy (PACE): A Randomized Phase II Study of Fulvestrant, Palbociclib, and Avelumab for Endocrine Pre-treated ER+/HER2- Metastatic Breast Cancer
Session: General Session #3
Location: Hall 3
Date: Thursday, Dec 8, 9:45 - 10:00 AM
Mayer EL, Ren Y, Wagle N, Mahtani R, Ma CX, DeMichele A, Cristofanilli M, Meisel J, Miller KD, Jolly T, Riley E, Qamar R, Sharma P, Reid S, Sinclair N, Faggen M, Block C, Ko N, Partridge AH, Chen WY, DeMeo MK, Attaya V, Okpoebo A, Liu Y, Gauthier E, Burstein H, Regan MM, Tolaney SM.
PD14-05 Prospective longitudinal validation of a breast cancer risk prediction model in a cohort of 130,058 women
Session: Spotlight Poster Discussion 14 - Breast Cancer Risk Modeling
Date: Thursday, Dec 8, 5:00 PM
Mabey B, Hughes E, Probst B, Pederson HJ, Simmons T, Morris B, Hullinger B, Domchek SM, Eng C, Gary M, Klemp J, Mukherjee S, Joseph V, Offit K, Olopade OI, Pruthi S, Kurian AW, Robson ME, Whitworth P, Wagner S, Lanchbury J, Slavin T, Gutin A.
December 9, 2022
P6-05-06 Patient-reported anxiety and fatigue in women enrolled in the RxPONDER trial (SWOG S1007) by menopausal status
Session: Poster Session #4 - Prognostic and Predictive Factors-Biomarkers Predicting Tx Response: Predictive Biomarkers for Chemo
Date: Friday, Dec 9, 7:00 AM
Loch MM, Forschmiedt JK, Kang IM, Gralow JR, Meric-Bernstam F, Albain KS, Hayes DF, Lin NU, Perez EA, Goldstein LJ, Rastogi P, Schott AF, Shak S, Sharma P, Lew DL, Miao J, Barlow WE, Tripathy D, Pusztai L, Hortobagyi GN, Kalinsky K, Henry NL.
P6-14-08 Epithelial/stromal cross talks that induce malignant transition of human ductal carcinoma in situ
Session: Poster Session #4 - Prognostic and Predictive Factors-Biomarkers Predicting Tx Response: Predictive Biomarkers for Chemo
Date: Friday, Dec 9, 7:00 AM
Rastogi A, Behbod F, Navin N, Lin J, Li L, Li H, Godwin AK, Thompson AM, Fields T, Hong Y.
State of the Cancer Center Presentation
Highlights
Hear from our faculty as they discuss major findings presented at ASCO 2020.